dbPTM

NFAC1_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	NFAC1_HUMAN
UniProt AC	O95644
Protein Name	Nuclear factor of activated T-cells, cytoplasmic 1
Gene Name	NFATC1
Organism	Homo sapiens (Human).
Sequence Length	943
Subcellular Localization	Cytoplasm . Nucleus . Cytoplasmic for the phosphorylated form and nuclear after activation that is controlled by calcineurin-mediated dephosphorylation. Rapid nuclear exit of NFATC is thought to be one mechanism by which cells distinguish between sus
Protein Description	Plays a role in the inducible expression of cytokine genes in T-cells, especially in the induction of the IL-2 or IL-4 gene transcription. Also controls gene expression in embryonic cardiac cells. Could regulate not only the activation and proliferation but also the differentiation and programmed death of T-lymphocytes as well as lymphoid and non-lymphoid cells. [PubMed: 10358178 Required for osteoclastogenesis and regulates many genes important for osteoclast differentiation and function (By similarity]
Protein Sequence	MPSTSFPVPSKFPLGPAAAVFGRGETLGPAPRAGGTMKSAEEEHYGYASSNVSPALPLPTAHSTLPAPCHNLQTSTPGIIPPADHPSGYGAALDGGPAGYFLSSGHTRPDGAPALESPRIEITSCLGLYHNNNQFFHDVEVEDVLPSSKRSPSTATLSLPSLEAYRDPSCLSPASSLSSRSCNSEASSYESNYSYPYASPQTSPWQSPCVSPKTTDPEEGFPRGLGACTLLGSPRHSPSTSPRASVTEESWLGARSSRPASPCNKRKYSLNGRQPPYSPHHSPTPSPHGSPRVSVTDDSWLGNTTQYTSSAIVAAINALTTDSSLDLGDGVPVKSRKTTLEQPPSVALKVEPVGEDLGSPPPPADFAPEDYSSFQHIRKGGFCDQYLAVPQHPYQWAKPKPLSPTSYMSPTLPALDWQLPSHSGPYELRIEVQPKSHHRAHYETEGSRGAVKASAGGHPIVQLHGYLENEPLMLQLFIGTADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLEIPLLPENSMRAVIDCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSLQVASNPIECSQRSAQELPLVEKQSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHHVWEMEAKTDRDLCKPNSLVVEIPPFRNQRITSPVHVSFYVCNGKRKRSQYQRFTYLPANVPIIKTEPTDDYEPAPTCGPVSQGLSPLPRPYYSQQLAMPPDPSSCLVAGFPPCPQRSTLMPAAPGVSPKLHDLSPAAYTKGVASPGHCHLGLPQPAGEAPAVQDVPRPVATHPGSPGQPPPALLPQQVSAPPSSSCPPGLEHSLCPSSPSPPLPPATQEPTCLQPCSPACPPATGRPQHLPSTVRRDESPTAGPRLLPEVHEDGSPNLAPIPVTVKREPEELDQLYLDDVNEIIRNDLSSTSTHS

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
23	Methylation	PAAAVFGRGETLGPA CCEEECCCCCCCCCC	28.45	115484845
117	Phosphorylation	DGAPALESPRIEITS CCCCCCCCCCEEEEE	21.96	-
123	Phosphorylation	ESPRIEITSCLGLYH CCCCEEEEEEEEEEE	10.70	30576142
141	Phosphorylation	QFFHDVEVEDVLPSS CEEEEEEHHHCCCCC	8.38	24719451
145	Phosphorylation	DVEVEDVLPSSKRSP EEEHHHCCCCCCCCC	5.42	24719451
147	Phosphorylation	EVEDVLPSSKRSPST EHHHCCCCCCCCCCC	44.31	26074081
148	Phosphorylation	VEDVLPSSKRSPSTA HHHCCCCCCCCCCCC	30.10	26074081
151	Phosphorylation	VLPSSKRSPSTATLS CCCCCCCCCCCCEEE	27.26	23401153
153	Phosphorylation	PSSKRSPSTATLSLP CCCCCCCCCCEEECC	31.74	23401153
154	Phosphorylation	SSKRSPSTATLSLPS CCCCCCCCCEEECCC	27.35	23401153
156	Phosphorylation	KRSPSTATLSLPSLE CCCCCCCEEECCCHH	19.57	27251275
158	Phosphorylation	SPSTATLSLPSLEAY CCCCCEEECCCHHHH	33.60	25850435
161	Phosphorylation	TATLSLPSLEAYRDP CCEEECCCHHHHCCH	44.10	23401153
165	Phosphorylation	SLPSLEAYRDPSCLS ECCCHHHHCCHHHCC	13.23	23401153
169	Phosphorylation	LEAYRDPSCLSPASS HHHHCCHHHCCCCHH	31.79	28450419
172	Phosphorylation	YRDPSCLSPASSLSS HCCHHHCCCCHHHCC	23.81	28450419
175	Phosphorylation	PSCLSPASSLSSRSC HHHCCCCHHHCCCCC	34.88	30576142
176	Phosphorylation	SCLSPASSLSSRSCN HHCCCCHHHCCCCCC	34.08	28450419
178	Phosphorylation	LSPASSLSSRSCNSE CCCCHHHCCCCCCCC	26.17	28450419
179	Phosphorylation	SPASSLSSRSCNSEA CCCHHHCCCCCCCCC	33.24	28450419
184	Phosphorylation	LSSRSCNSEASSYES HCCCCCCCCCHHCCC	38.58	-
187	Phosphorylation	RSCNSEASSYESNYS CCCCCCCHHCCCCCC	29.42	10652349
197	Phosphorylation	ESNYSYPYASPQTSP CCCCCCCCCCCCCCC	16.10	-
211	Phosphorylation	PWQSPCVSPKTTDPE CCCCCCCCCCCCCHH	27.65	28348404
220	Phosphorylation	KTTDPEEGFPRGLGA CCCCHHCCCCCCCCC	35.88	24719451
224	Phosphorylation	PEEGFPRGLGACTLL HHCCCCCCCCCHHHC	28.80	24719451
227	Phosphorylation	GFPRGLGACTLLGSP CCCCCCCCHHHCCCC	6.53	24719451
229	Phosphorylation	PRGLGACTLLGSPRH CCCCCCHHHCCCCCC	25.20	23927012
232	Phosphorylation	LGACTLLGSPRHSPS CCCHHHCCCCCCCCC	38.42	24719451
233	Phosphorylation	GACTLLGSPRHSPST CCHHHCCCCCCCCCC	20.80	19664994
237	Phosphorylation	LLGSPRHSPSTSPRA HCCCCCCCCCCCCCC	23.09	23401153
239	Phosphorylation	GSPRHSPSTSPRASV CCCCCCCCCCCCCCC	44.52	23401153
240	Phosphorylation	SPRHSPSTSPRASVT CCCCCCCCCCCCCCC	46.24	28152594
241	Phosphorylation	PRHSPSTSPRASVTE CCCCCCCCCCCCCCC	19.41	23927012
245	Phosphorylation	PSTSPRASVTEESWL CCCCCCCCCCCCHHC	30.74	9072970
247	Phosphorylation	TSPRASVTEESWLGA CCCCCCCCCCHHCCC	31.38	23403867
248	Phosphorylation	SPRASVTEESWLGAR CCCCCCCCCHHCCCC	48.13	24719451
250	Phosphorylation	RASVTEESWLGARSS CCCCCCCHHCCCCCC	22.74	23403867
256	Phosphorylation	ESWLGARSSRPASPC CHHCCCCCCCCCCCC	30.11	9072970
257	Phosphorylation	SWLGARSSRPASPCN HHCCCCCCCCCCCCC	36.41	28985074
261	Phosphorylation	ARSSRPASPCNKRKY CCCCCCCCCCCCCCC	32.44	26437602
268	Phosphorylation	SPCNKRKYSLNGRQP CCCCCCCCCCCCCCC	23.56	27251275
269	Phosphorylation	PCNKRKYSLNGRQPP CCCCCCCCCCCCCCC	20.56	23401153
277	Phosphorylation	LNGRQPPYSPHHSPT CCCCCCCCCCCCCCC	41.33	28450419
278	Phosphorylation	NGRQPPYSPHHSPTP CCCCCCCCCCCCCCC	24.43	28450419
282	Phosphorylation	PPYSPHHSPTPSPHG CCCCCCCCCCCCCCC	27.69	28450419
284	Phosphorylation	YSPHHSPTPSPHGSP CCCCCCCCCCCCCCC	39.14	28450419
286	Phosphorylation	PHHSPTPSPHGSPRV CCCCCCCCCCCCCCE	31.82	28450419
290	Phosphorylation	PTPSPHGSPRVSVTD CCCCCCCCCCEEECC	13.39	29523821
294	Phosphorylation	PHGSPRVSVTDDSWL CCCCCCEEECCCCCC	22.15	8202141
324	Phosphorylation	NALTTDSSLDLGDGV HHHCCCCCCCCCCCC	28.81	-
335	Phosphorylation	GDGVPVKSRKTTLEQ CCCCCCCCCCCCCCC	38.96	23882029
337	Ubiquitination	GVPVKSRKTTLEQPP CCCCCCCCCCCCCCC	53.61	-
338	Phosphorylation	VPVKSRKTTLEQPPS CCCCCCCCCCCCCCC	35.19	23882029
339	Phosphorylation	PVKSRKTTLEQPPSV CCCCCCCCCCCCCCE	31.19	23882029
345	Phosphorylation	TTLEQPPSVALKVEP CCCCCCCCEEEEEEE	27.06	-
346	Phosphorylation	TLEQPPSVALKVEPV CCCCCCCEEEEEEEC	9.98	24719451
349	Sumoylation	QPPSVALKVEPVGED CCCCEEEEEEECCCC	34.51	-
349	Sumoylation	QPPSVALKVEPVGED CCCCEEEEEEECCCC	34.51	-
359	Phosphorylation	PVGEDLGSPPPPADF ECCCCCCCCCCCCCC	41.34	30266825
371	Phosphorylation	ADFAPEDYSSFQHIR CCCCCCCHHCCCHHH	12.45	30266825
373	Phosphorylation	FAPEDYSSFQHIRKG CCCCCHHCCCHHHCC	23.77	26074081
379	Ubiquitination	SSFQHIRKGGFCDQY HCCCHHHCCCCCCCE	63.88	-
386	Phosphorylation	KGGFCDQYLAVPQHP CCCCCCCEEECCCCC	5.38	-
392	Phosphorylation	QYLAVPQHPYQWAKP CEEECCCCCCCCCCC	19.57	24719451
394	Phosphorylation	LAVPQHPYQWAKPKP EECCCCCCCCCCCCC	17.98	-
398	Ubiquitination	QHPYQWAKPKPLSPT CCCCCCCCCCCCCCC	51.09	-
403	Phosphorylation	WAKPKPLSPTSYMSP CCCCCCCCCCCCCCC	34.36	27251275
405	Phosphorylation	KPKPLSPTSYMSPTL CCCCCCCCCCCCCCC	29.16	24719451
406	Phosphorylation	PKPLSPTSYMSPTLP CCCCCCCCCCCCCCC	23.40	27251275
409	Phosphorylation	LSPTSYMSPTLPALD CCCCCCCCCCCCCCC	13.39	-
426	Phosphorylation	LPSHSGPYELRIEVQ CCCCCCCEEEEEEEE	30.99	-
442	Phosphorylation	KSHHRAHYETEGSRG CCCCCCEEECCCCCC	24.46	23403867
447	Phosphorylation	AHYETEGSRGAVKAS CEEECCCCCCCEEHH	22.70	23403867
501	Phosphorylation	VHRITGKTVSTTSHE EEEECCCEEECCCHH	22.49	28122231
503	Phosphorylation	RITGKTVSTTSHEAI EECCCEEECCCHHHH	31.06	28122231
504	Phosphorylation	ITGKTVSTTSHEAIL ECCCEEECCCHHHHH	28.16	28122231
505	Phosphorylation	TGKTVSTTSHEAILS CCCEEECCCHHHHHC	22.15	28122231
506	Phosphorylation	GKTVSTTSHEAILSN CCEEECCCHHHHHCC	21.30	28122231
512	Phosphorylation	TSHEAILSNTKVLEI CCHHHHHCCCCEEEE	36.02	28122231
514	Phosphorylation	HEAILSNTKVLEIPL HHHHHCCCCEEEECC	21.10	28122231
526	Phosphorylation	IPLLPENSMRAVIDC ECCCCCCCHHHHHHH	14.16	-
538	Ubiquitination	IDCAGILKLRNSDIE HHHHHHHHHHCCCCE	43.40	-
538	Ubiquitination	IDCAGILKLRNSDIE HHHHHHHHHHCCCCE	43.40	-
542	Phosphorylation	GILKLRNSDIELRKG HHHHHHCCCCEECCC	33.27	28450419
548	Ubiquitination	NSDIELRKGETDIGR CCCCEECCCCCCCCC	73.96	-
612	Acetylation	SYPVVGGKKMVLSGH CCCEECCEEEEECCC	31.59	19817897
617	Phosphorylation	GGKKMVLSGHNFLQD CCEEEEECCCCCCCC	26.96	26074081
625	Phosphorylation	GHNFLQDSKVIFVEK CCCCCCCCEEEEEEE	18.83	26074081
626	Acetylation	HNFLQDSKVIFVEKA CCCCCCCEEEEEEEC	47.87	19817907
657	Phosphorylation	LCKPNSLVVEIPPFR HCCCCEEEEECCCCC	3.49	24719451
669	Phosphorylation	PFRNQRITSPVHVSF CCCCCCCCCCEEEEE	29.21	28450419
670	Phosphorylation	FRNQRITSPVHVSFY CCCCCCCCCEEEEEE	23.66	28450419
675	Phosphorylation	ITSPVHVSFYVCNGK CCCCEEEEEEEECCC	8.93	23186163
677	Phosphorylation	SPVHVSFYVCNGKRK CCEEEEEEEECCCCC	9.15	23186163
702	Sumoylation	PANVPIIKTEPTDDY CCCCCEEECCCCCCC	47.78	-
702	Sumoylation	PANVPIIKTEPTDDY CCCCCEEECCCCCCC	47.78	-
703	Phosphorylation	ANVPIIKTEPTDDYE CCCCEEECCCCCCCC	36.47	28796482
706	Phosphorylation	PIIKTEPTDDYEPAP CEEECCCCCCCCCCC	34.96	28796482
709	Phosphorylation	KTEPTDDYEPAPTCG ECCCCCCCCCCCCCC	26.99	28796482
723	Phosphorylation	GPVSQGLSPLPRPYY CCCCCCCCCCCCCCC	31.08	24719451
752	Phosphorylation	VAGFPPCPQRSTLMP EECCCCCCCCCCCCC	38.09	24719451
759	Phosphorylation	PQRSTLMPAAPGVSP CCCCCCCCCCCCCCC	28.51	24719451
765	Phosphorylation	MPAAPGVSPKLHDLS CCCCCCCCCCHHHCC	23.41	28985074
772	Phosphorylation	SPKLHDLSPAAYTKG CCCHHHCCHHHHCCC	20.67	28450419
776	Phosphorylation	HDLSPAAYTKGVASP HHCCHHHHCCCCCCC	15.87	26074081
777	Phosphorylation	DLSPAAYTKGVASPG HCCHHHHCCCCCCCC	19.32	26074081
782	Phosphorylation	AYTKGVASPGHCHLG HHCCCCCCCCCCCCC	29.07	26074081
813	Phosphorylation	PVATHPGSPGQPPPA CCCCCCCCCCCCCCC	30.24	27251275
874	Phosphorylation	ACPPATGRPQHLPST CCCCCCCCCCCCCCC	24.29	24719451
887	Phosphorylation	STVRRDESPTAGPRL CCCCCCCCCCCCCCC	31.66	23401153
889	Phosphorylation	VRRDESPTAGPRLLP CCCCCCCCCCCCCCC	54.23	29255136
890	Phosphorylation	RRDESPTAGPRLLPE CCCCCCCCCCCCCCC	29.40	24719451
903	Phosphorylation	PEVHEDGSPNLAPIP CCCCCCCCCCCCCCC	23.96	30266825
912	Phosphorylation	NLAPIPVTVKREPEE CCCCCCEEECCCHHH	18.24	26074081
914	Sumoylation	APIPVTVKREPEELD CCCCEEECCCHHHHH	41.50	-
914	Sumoylation	APIPVTVKREPEELD CCCCEEECCCHHHHH	41.50	-
924	Phosphorylation	PEELDQLYLDDVNEI HHHHHHHEHHHHHHH	11.49	27642862

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
117	S	Phosphorylation	Kinase	IKBKE	Q14164	GPS
151	S	Phosphorylation	Kinase	PIM1	P11309	PSP
151	S	Phosphorylation	Kinase	IKBKE	Q14164	GPS
153	S	Phosphorylation	Kinase	PIM1	P11309	PSP
154	T	Phosphorylation	Kinase	PIM1	P11309	PSP
161	S	Phosphorylation	Kinase	IKBKE	Q14164	GPS
172	S	Phosphorylation	Kinase	MAPK14	Q16539	GPS
172	S	Phosphorylation	Kinase	MAPK10	P53779	GPS
172	S	Phosphorylation	Kinase	MAPK8	P45983	GPS
172	S	Phosphorylation	Kinase	MAPK3	P27361	GPS
187	S	Phosphorylation	Kinase	CSNK2A1	P19139	GPS
241	S	Phosphorylation	Kinase	ROCK2	O75116	PSP
245	S	Phosphorylation	Kinase	PRKACA	P05132	GPS
245	S	Phosphorylation	Kinase	PKA-FAMILY	-	GPS
245	S	Phosphorylation	Kinase	PKACA	P17612	PSP
245	S	Phosphorylation	Kinase	PKA	-	Uniprot
245	S	Phosphorylation	Kinase	PIM1	P11309	PSP
245	S	Phosphorylation	Kinase	PKA_GROUP	-	PhosphoELM
256	S	Phosphorylation	Kinase	PIM1	P11309	PSP
257	S	Phosphorylation	Kinase	PIM1	P11309	PSP
261	S	Phosphorylation	Kinase	DYRK1A	Q13627	PSP
269	S	Phosphorylation	Kinase	PKA_GROUP	-	PhosphoELM
269	S	Phosphorylation	Kinase	PKA-FAMILY	-	GPS
269	S	Phosphorylation	Kinase	PKA	-	Uniprot
269	S	Phosphorylation	Kinase	PIM1	P11309	PSP
269	S	Phosphorylation	Kinase	PRKACA	P05132	GPS
269	S	Phosphorylation	Kinase	PKACA	P17612	PSP
278	S	Phosphorylation	Kinase	PIM1	P11309	PSP
278	S	Phosphorylation	Kinase	DYRK1A	Q13627	PSP
294	S	Phosphorylation	Kinase	PRKACA	P17612	GPS
294	S	Phosphorylation	Kinase	PKA-FAMILY	-	GPS
294	S	Phosphorylation	Kinase	PKA	-	Uniprot
294	S	Phosphorylation	Kinase	PKA_GROUP	-	PhosphoELM
324	S	Phosphorylation	Kinase	IKBKE	Q14164	GPS
335	S	Phosphorylation	Kinase	PIM1	P11309	PSP
338	T	Phosphorylation	Kinase	PIM1	P11309	PSP
339	T	Phosphorylation	Kinase	PIM1	P11309	PSP
371	Y	Phosphorylation	Kinase	JAK3	P52333	PSP
403	S	Phosphorylation	Kinase	DYRK1A	Q13627	PSP
409	S	Phosphorylation	Kinase	DYRK1A	Q13627	PSP
-	K	Ubiquitination	E3 ubiquitin ligase	CBL	P22681	PMID:22199232

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of NFAC1_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of NFAC1_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
EGR1_HUMAN	EGR1	physical	12560487
EGR2_HUMAN	EGR2	physical	12560487
PARP1_HUMAN	PARP1	physical	18078995
FOXP3_HUMAN	FOXP3	physical	21490927
HDAC5_HUMAN	HDAC5	physical	21413932
TBA1A_HUMAN	TUBA1A	physical	21278340
IMB1_HUMAN	KPNB1	physical	21278340
UBC9_HUMAN	UBE2I	physical	19218564
PIAS1_HUMAN	PIAS1	physical	19218564
KS6A3_HUMAN	RPS6KA3	physical	22113269
KS6B1_HUMAN	RPS6KB1	physical	22113269
PML_HUMAN	PML	physical	18246125
OGT1_HUMAN	OGT	physical	17882263
EP300_HUMAN	EP300	physical	15117818
JUN_HUMAN	JUN	physical	25609649
HXD13_HUMAN	HOXD13	physical	25609649
CREB1_HUMAN	CREB1	physical	25609649
H2B1A_HUMAN	HIST1H2BA	physical	25609649
H31T_HUMAN	HIST3H3	physical	25609649
ATF3_HUMAN	ATF3	physical	25609649
P53_HUMAN	TP53	physical	25609649
CHD4_HUMAN	CHD4	physical	25609649
ZMYM3_HUMAN	ZMYM3	physical	25609649
ISL1_HUMAN	ISL1	physical	25609649
SMCA5_HUMAN	SMARCA5	physical	25609649
ADNP_HUMAN	ADNP	physical	25609649
CUX1_HUMAN	CUX1	physical	25609649
CASP_HUMAN	CUX1	physical	25609649
H2A1D_HUMAN	HIST1H2AD	physical	25609649
RECQ1_HUMAN	RECQL	physical	25609649
ATF1_HUMAN	ATF1	physical	25609649
FWCH1_HUMAN	FLYWCH1	physical	25609649
P66B_HUMAN	GATAD2B	physical	25609649
HMGA1_HUMAN	HMGA1	physical	25609649
SMC3_HUMAN	SMC3	physical	25609649
ATF2_HUMAN	ATF2	physical	25609649
BEND3_HUMAN	BEND3	physical	25609649
KIF4A_HUMAN	KIF4A	physical	25609649
LRWD1_HUMAN	LRWD1	physical	25609649
SMC2_HUMAN	SMC2	physical	25609649
FRPD1_HUMAN	FRMPD1	physical	25609649
HDAC2_HUMAN	HDAC2	physical	25609649
HMGA2_HUMAN	HMGA2	physical	25609649
HXA10_HUMAN	HOXA10	physical	25609649
JUND_HUMAN	JUND	physical	25609649
ORC2_HUMAN	ORC2	physical	25609649
ORC5_HUMAN	ORC5	physical	25609649
PDS5A_HUMAN	PDS5A	physical	25609649
PRD15_HUMAN	PRDM15	physical	25609649
SMCA4_HUMAN	SMARCA4	physical	25609649
SNF5_HUMAN	SMARCB1	physical	25609649
SMRC2_HUMAN	SMARCC2	physical	25609649
TAF10_HUMAN	TAF10	physical	25609649
TRPS1_HUMAN	TRPS1	physical	25609649
A20A1_HUMAN	ANKRD20A1	physical	25609649
RPTOR_HUMAN	RPTOR	physical	27637333
CREB1_HUMAN	CREB1	physical	27637333
SCAI_HUMAN	SCAI	physical	27637333
GSK3B_HUMAN	GSK3B	physical	27637333
WDR48_HUMAN	WDR48	physical	27637333
IKZF2_HUMAN	IKZF2	physical	27637333
CHK1_HUMAN	CHEK1	physical	27637333
IKZF1_HUMAN	IKZF1	physical	27637333
SATB1_HUMAN	SATB1	physical	27637333
RUNX1_HUMAN	RUNX1	physical	27637333
EP300_HUMAN	EP300	physical	27637333
JUN_HUMAN	JUN	physical	27637333
FOS_HUMAN	FOS	physical	27637333
KC1D_HUMAN	CSNK1D	physical	27637333
TR61B_HUMAN	TRMT61B	physical	27637333
MSPD2_HUMAN	MOSPD2	physical	27637333
RFC5_HUMAN	RFC5	physical	27637333
NEK7_HUMAN	NEK7	physical	27637333
NEK6_HUMAN	NEK6	physical	27637333
FOXK2_HUMAN	FOXK2	physical	27637333
SERA_HUMAN	PHGDH	physical	27637333
JUNB_HUMAN	JUNB	physical	27637333
CBP_HUMAN	CREBBP	physical	27637333
MTDC_HUMAN	MTHFD2	physical	27637333
LRC47_HUMAN	LRRC47	physical	27637333
NFAC2_HUMAN	NFATC2	physical	27637333
FXR1_HUMAN	FXR1	physical	27637333
ACAD9_HUMAN	ACAD9	physical	27637333
ZBT40_HUMAN	ZBTB40	physical	27637333
RANB9_HUMAN	RANBP9	physical	27637333
REQU_HUMAN	DPF2	physical	27637333
SMRC2_HUMAN	SMARCC2	physical	27637333
SMRD2_HUMAN	SMARCD2	physical	27637333
LEF1_HUMAN	LEF1	physical	27637333
RFC2_HUMAN	RFC2	physical	27637333
VAPA_HUMAN	VAPA	physical	27637333
ATF7_HUMAN	ATF7	physical	27637333
SMCE1_HUMAN	SMARCE1	physical	27637333
IF16_HUMAN	IFI16	physical	27637333
CHAP1_HUMAN	CHAMP1	physical	27637333
MDHM_HUMAN	MDH2	physical	27637333
XRCC6_HUMAN	XRCC6	physical	27637333
HLTF_HUMAN	HLTF	physical	27637333
DNJC7_HUMAN	DNAJC7	physical	27637333
C1TM_HUMAN	MTHFD1L	physical	27637333
PEBB_HUMAN	CBFB	physical	27637333
XRCC5_HUMAN	XRCC5	physical	27637333
SMCA4_HUMAN	SMARCA4	physical	27637333
ACL6A_HUMAN	ACTL6A	physical	27637333
RFA1_HUMAN	RPA1	physical	27637333
CTBP1_HUMAN	CTBP1	physical	27637333
SMRC1_HUMAN	SMARCC1	physical	27637333
GRP78_HUMAN	HSPA5	physical	27637333
RFC4_HUMAN	RFC4	physical	27637333
FOXK1_HUMAN	FOXK1	physical	27637333
GRP75_HUMAN	HSPA9	physical	27637333
SMRD1_HUMAN	SMARCD1	physical	27637333
ARI1A_HUMAN	ARID1A	physical	27637333
DNLI3_HUMAN	LIG3	physical	27637333
EFTU_HUMAN	TUFM	physical	27637333
PO210_HUMAN	NUP210	physical	27637333
SYSM_HUMAN	SARS2	physical	27637333
BC11B_HUMAN	BCL11B	physical	27637333
TRRAP_HUMAN	TRRAP	physical	27637333
KC1A_HUMAN	CSNK1A1	physical	27637333
KC1AL_HUMAN	CSNK1A1L	physical	27637333
PYR1_HUMAN	CAD	physical	27637333
HMCS2_HUMAN	HMGCS2	physical	28514442
PLOD1_HUMAN	PLOD1	physical	28514442
CANB1_HUMAN	PPP3R1	physical	28514442
OBSL1_HUMAN	OBSL1	physical	28514442
KTU_HUMAN	DNAAF2	physical	28514442
SEM7A_HUMAN	SEMA7A	physical	28514442
ZMY19_HUMAN	ZMYND19	physical	28514442
MKLN1_HUMAN	MKLN1	physical	28514442
LRC28_HUMAN	LRRC28	physical	28514442
ARMC8_HUMAN	ARMC8	physical	28514442
PP2BA_HUMAN	PPP3CA	physical	28514442

Drug and Disease Associations

Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
DB00852	Pseudoephedrine

Regulatory Network of NFAC1_HUMAN

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"Lys-N and trypsin cover complementary parts of the phosphoproteome ina refined SCX-based approach."; Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J.,Mohammed S.; Anal. Chem. 81:4493-4501(2009). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-233, AND MASSSPECTROMETRY.	19413330 [Abstract]