PRD15_HUMAN - dbPTM
PRD15_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID PRD15_HUMAN
UniProt AC P57071
Protein Name PR domain zinc finger protein 15
Gene Name PRDM15
Organism Homo sapiens (Human).
Sequence Length 1507
Subcellular Localization Nucleus .
Protein Description May be involved in transcriptional regulation..
Protein Sequence MPRRRPPASGAAQFPERIATRSPDPIPLCTFQRQPRAAPVQPPCRLFFVTFAGCGHRWRSESKPGWISRSRSGIALRAARPPGSSPPRPAAPRPPPPGGVVAEAPGDVVIPRPRVQPMRVARGGPWTPNPAFREAESWSQIGNQRVSEQLLETSLGNEVSDTEPLSPASAGLRRNPALPPGPFAQNFSWGNQENLPPALGKIANGGGTGAGKAECGYETESHLLEPHEIPLNVNTHKFSDCEFPYEFCTVCFSPFKLLGMSGVEGVWNQHSRSASMHTFLNHSATGIREAGCRKDMPVSEMAEDGSEEIMFIWCEDCSQYHDSECPELGPVVMVKDSFVLSRARSWPASGHVHTQAGQGMRGYEDRDRADPQQLPEAVPAGLVRRLSGQQLPCRSTLTWGRLCHLVAQGRSSLPPNLEIRRLEDGAEGVFAITQLVKRTQFGPFESRRVAKWEKESAFPLKVFQKDGHPVCFDTSNEDDCNWMMLVRPAAEAEHQNLTAYQHGSDVYFTTSRDIPPGTELRVWYAAFYAKKMDKPMLKQAGSGVHAAGTPENSAPVESEPSQWACKVCSATFLELQLLNEHLLGHLEQAKSLPPGSQSEAAAPEKEQDTPRGEPPAVPESENVATKEQKKKPRRGRKPKVSKAEQPLVIVEDKEPTEQVAEIITEVPPDEPVSATPDERIMELVLGKLATTTTDTSSVPKFTHHQNNTITLKRSLILSSRHGIRRKLIKQLGEHKRVYQCNICSKIFQNSSNLSRHVRSHGDKLFKCEECAKLFSRKESLKQHVSYKHSRNEVDGEYRYRCGTCEKTFRIESALEFHNCRTDDKTFQCEMCFRFFSTNSNLSKHKKKHGDKKFACEVCSKMFYRKDVMLDHQRRHLEGVRRVKREDLEAGGENLVRYKKEPSGCPVCGKVFSCRSNMNKHLLTHGDKKYTCEICGRKFFRVDVLRDHIHVHFKDIALMDDHQREEFIGKIGISSEENDDNSDESADSEPHKYSCKRCQLTFGRGKEYLKHIMEVHKEKGYGCSICNRRFALKATYHAHMVIHRENLPDPNVQKYIHPCEICGRIFNSIGNLERHKLIHTGVKSHACEQCGKSFARKDMLKEHMRVHDNVREYLCAECGKGMKTKHALRHHMKLHKGIKEYECKECHRRFAQKVNMLKHCKRHTGIKDFMCELCGKTFSERNTMETHKLIHTVGKQWTCSVCDKKYVTEYMLQKHVQLTHDKVEAQSCQLCGTKVSTRASMSRHMRRKHPEVLAVRIDDLDHLPETTTIDASSIGIVQPELTLEQEDLAEGKHGKAAKRSHKRKQKPEEEAGAPVPEDATFSEYSEKETEFTGSVGDETNSAVQSIQQVVVTLGDPNVTTPSSSVGLTNITVTPITTAAATQFTNLQPVAVGHLTTPERQLQLDNSILTVTFDTVSGSAMLHNRQNDVQIHPQPEASNPQSVAHFINLTTLVNSITPLGSQLSDQHPLTWRAVPQTDVLPPSQPQAPPQQAAQPQVQAEQQQQQMYSY
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
20PhosphorylationQFPERIATRSPDPIP
CCCHHHCCCCCCCCC		29.34-
22PhosphorylationPERIATRSPDPIPLC
CHHHCCCCCCCCCCC		29.3325850435
60PhosphorylationGCGHRWRSESKPGWI
CCCCCCCCCCCCCCC		38.9829632367
62PhosphorylationGHRWRSESKPGWISR
CCCCCCCCCCCCCCC		45.4529632367
68PhosphorylationESKPGWISRSRSGIA
CCCCCCCCCCCCCEE		20.0729632367
345PhosphorylationFVLSRARSWPASGHV
EEEECCCCCCCCCCE		36.1025850435
349PhosphorylationRARSWPASGHVHTQA
CCCCCCCCCCEECCC		25.9225850435
354PhosphorylationPASGHVHTQAGQGMR
CCCCCEECCCCCCCC		21.0125850435
482 (in isoform 6)Phosphorylation-4.6622210691
504 (in isoform 6)Phosphorylation-23.0630631047
505 (in isoform 6)Phosphorylation-43.6730631047
518PhosphorylationSRDIPPGTELRVWYA
CCCCCCCCCHHHHHH		37.3124719451
522 (in isoform 5)Phosphorylation-7.7722210691
542PhosphorylationPMLKQAGSGVHAAGT
HHHHHCCCCCCCCCC		40.4328450419
544 (in isoform 5)Phosphorylation-2.7330631047
545 (in isoform 5)Phosphorylation-17.2430631047
549PhosphorylationSGVHAAGTPENSAPV
CCCCCCCCCCCCCCC		23.7828450419
553PhosphorylationAAGTPENSAPVESEP
CCCCCCCCCCCCCCC		32.0828450419
687UbiquitinationIMELVLGKLATTTTD
HHHHHHHHHCCCCCC		30.68-
692PhosphorylationLGKLATTTTDTSSVP
HHHHCCCCCCCCCCC		20.5130576142
693PhosphorylationGKLATTTTDTSSVPK
HHHCCCCCCCCCCCC		34.8830576142
714PhosphorylationNTITLKRSLILSSRH
CEEEEEHHHHHHCCH		20.4130301811
718PhosphorylationLKRSLILSSRHGIRR
EEHHHHHHCCHHHHH		20.5224719451
719PhosphorylationKRSLILSSRHGIRRK
EHHHHHHCCHHHHHH		25.5024719451
729UbiquitinationGIRRKLIKQLGEHKR
HHHHHHHHHHCCCCC		50.32-
777UbiquitinationCAKLFSRKESLKQHV
HHHHHCCHHHHHHHC		50.92-
883SumoylationLEGVRRVKREDLEAG
HHHHHHHCHHHHHCC		48.54-
883SumoylationLEGVRRVKREDLEAG
HHHHHHHCHHHHHCC		48.5428112733
973PhosphorylationFIGKIGISSEENDDN
HHHHCCCCCCCCCCC		26.8729449344
974PhosphorylationIGKIGISSEENDDNS
HHHCCCCCCCCCCCC		47.1929449344
981PhosphorylationSEENDDNSDESADSE
CCCCCCCCCCCCCCC		50.1525849741
984PhosphorylationNDDNSDESADSEPHK
CCCCCCCCCCCCCCC		42.2224247654
987PhosphorylationNSDESADSEPHKYSC
CCCCCCCCCCCCCCC		53.3929449344
992PhosphorylationADSEPHKYSCKRCQL
CCCCCCCCCCCCCCC		19.1029449344
993PhosphorylationDSEPHKYSCKRCQLT
CCCCCCCCCCCCCCE		20.2629449344
996MethylationPHKYSCKRCQLTFGR
CCCCCCCCCCCEECC		20.1024411157
1140PhosphorylationLHKGIKEYECKECHR
HCCCCCCCCCHHHHH		22.94-
1197PhosphorylationHTVGKQWTCSVCDKK
EECCCCCEEEECCHH		7.7530576142
1205PhosphorylationCSVCDKKYVTEYMLQ
EEECCHHHHHHHHHH		20.5322817900
1207PhosphorylationVCDKKYVTEYMLQKH
ECCHHHHHHHHHHHH		20.5029209046
1209PhosphorylationDKKYVTEYMLQKHVQ
CHHHHHHHHHHHHCC		8.1830576142
1218PhosphorylationLQKHVQLTHDKVEAQ
HHHHCCCCCCHHHHH		15.7830576142
1236PhosphorylationLCGTKVSTRASMSRH
CCCCCHHHHHHHHHH		32.9926270265
1239PhosphorylationTKVSTRASMSRHMRR
CCHHHHHHHHHHHHH		17.6326270265
1241PhosphorylationVSTRASMSRHMRRKH
HHHHHHHHHHHHHHC		19.2826270265
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of PRD15_HUMAN !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of PRD15_HUMAN !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of PRD15_HUMAN !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of PRD15_HUMAN !!
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of PRD15_HUMAN

loading...

Related Literatures of Post-Translational Modification

TOP
© 2024 Institute of Bioinformatics and Systems Biology, NYCU | Designed by : BiOmics Laboratory