LRC28_HUMAN - dbPTM
LRC28_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID LRC28_HUMAN
UniProt AC Q86X40
Protein Name Leucine-rich repeat-containing protein 28
Gene Name LRRC28
Organism Homo sapiens (Human).
Sequence Length 367
Subcellular Localization
Protein Description
Protein Sequence MASELCKTISVARLEKHKNLFLNYRNLHHFPLELLKDEGLQYLERLYMKRNSLTSLPENLAQKLPNLVELYLHSNNIVVVPEAIGSLVKLQCLDLSDNALEIVCPEIGRLRALRHLRLANNQLQFLPPEVGDLKELQTLDISTNRLLTLPERLHMCLSLQYLTVDRNRLWYVPRHLCQLPSLNELSMAGNRLAFLPLDLGRSRELQYVYVDNNIHLKGLPSYLYNKVIGCSGCGAPIQVSEVKLLSFSSGQRTVFLPAEVKAIGTEHDHVLPLQELAMRGLYHTYHSLLKDLNFLSPISLPRSLLELLHCPLGHCHRCSEPMFTIVYPKLFPLRETPMAGLHQWKTTVSFVAYCCSTQCLQTFDLLS
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
7Ubiquitination-MASELCKTISVARL
-CHHHHHHHCHHHHH		62.61-
18UbiquitinationVARLEKHKNLFLNYR
HHHHHHHCCCCCCCC		67.43-
36UbiquitinationHFPLELLKDEGLQYL
CCCHHHHHHHHHHHH		67.37-
52PhosphorylationRLYMKRNSLTSLPEN
HHHHHHCCCCCCCHH		36.7423312004
54PhosphorylationYMKRNSLTSLPENLA
HHHHCCCCCCCHHHH		28.2128122231
55PhosphorylationMKRNSLTSLPENLAQ
HHHCCCCCCCHHHHH		47.4128122231
134 (in isoform 2)Ubiquitination-62.2021906983
134 (in isoform 1)Ubiquitination-62.2021906983
134UbiquitinationPPEVGDLKELQTLDI
CCCCCCHHHCEEEEC		62.202190698
217UbiquitinationVDNNIHLKGLPSYLY
ECCCEEECCCCHHHH		44.21-
221PhosphorylationIHLKGLPSYLYNKVI
EEECCCCHHHHCCCC		32.5826074081
222PhosphorylationHLKGLPSYLYNKVIG
EECCCCHHHHCCCCC		15.9726074081
224PhosphorylationKGLPSYLYNKVIGCS
CCCCHHHHCCCCCCC		12.5226074081
226UbiquitinationLPSYLYNKVIGCSGC
CCHHHHCCCCCCCCC		22.98-
243UbiquitinationPIQVSEVKLLSFSSG
CCEEEEEEEEEECCC		39.39-
246PhosphorylationVSEVKLLSFSSGQRT
EEEEEEEEECCCCCE		33.2525072903
248PhosphorylationEVKLLSFSSGQRTVF
EEEEEEECCCCCEEE		30.1325072903
249PhosphorylationVKLLSFSSGQRTVFL
EEEEEECCCCCEEEE		36.6125072903
253PhosphorylationSFSSGQRTVFLPAEV
EECCCCCEEEEECEE		14.0224719451
261UbiquitinationVFLPAEVKAIGTEHD
EEEECEEEEECCCCC		26.28-
287PhosphorylationGLYHTYHSLLKDLNF
HHHHHHHHHHHHCCC		25.6124719451
299PhosphorylationLNFLSPISLPRSLLE
CCCCCCCCCCHHHHH		35.3924719451
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of LRC28_HUMAN !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of LRC28_HUMAN !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of LRC28_HUMAN !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
CH60_HUMANHSPD1physical
26186194
HSP7C_HUMANHSPA8physical
26186194
HSP76_HUMANHSPA6physical
26186194
HS71L_HUMANHSPA1Lphysical
26186194
TCPH_HUMANCCT7physical
26186194
CUL5_HUMANCUL5physical
28514442
CH60_HUMANHSPD1physical
28514442
HSP7C_HUMANHSPA8physical
28514442
Drug and Disease Associations
Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of LRC28_HUMAN

loading...

Related Literatures of Post-Translational Modification

TOP
© 2024 Institute of Bioinformatics and Systems Biology, NYCU | Designed by : BiOmics Laboratory