| UniProt ID | NDOR1_YEAST | |
|---|---|---|
| UniProt AC | Q12181 | |
| Protein Name | NADPH-dependent diflavin oxidoreductase 1 {ECO:0000255|HAMAP-Rule:MF_03178} | |
| Gene Name | TAH18 {ECO:0000255|HAMAP-Rule:MF_03178} | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 623 | |
| Subcellular Localization | Cytoplasm . Mitochondrion . Relocalizes to mitochondria after H(2)O(2) exposure. | |
| Protein Description | Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis. Transfers electrons from NADPH to the Fe-S cluster of DRE2. Positively controls H(2)O(2)-induced cell death.. | |
| Protein Sequence | MSSSKKIVILYGSETGNAHDFATILSHRLHRWHFSHTFCSIGDYDPQDILKCRYLFIICSTTGQGELPRNVNALKGERPVTFWSFLKRKNLPSNLLNHIQTAMLGLGDSSYPKFNYGIRKLHQRIVTQLGANELFDRLEADDQAMAGSNKGTGLGIESVYFEYEKKVLSFLLSKYPNRKVNGQIIKREELDPEVYLEPASYLQLSDEHANEKFTSTKVIFEGDESLKVGRVNINKRITSEGHFQDVRQFKFSNVDKIQENYEPGDTVTIYPCNTDEDVSRFLANQSHWLEIADKPLNFTSGVPNDLKDGGLVRPMTLRNLLKYHCDFMSIPRTSFFLKIWTFATDVTKMERGQEQLNDQREKLRQFATDQDMQDLYDYCNRPRRSILEVLEDFISVKLPWKYVLDYLPIIKPRYYSISSGPGDPNIELTVAIVKYKTILRKIRRGICTNYIARLQEGEQIRYKLQNNHIIKKEFLNKPMILVGPGVGLAPLLSVVKAEISKDIKLLFGCRYKDKDYIYKDMLEDWFRKGKIALHSSFSRDEENSPGVKYVQDYLWRLGEEITNLVVNKDAVFFLCGSSGKMPIQVRLTFIEMLKKWGNFSDEETAKKYLKEMEKSDRYIQETW | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 93 | Phosphorylation | LKRKNLPSNLLNHIQ HHHCCCCHHHHHHHH | 27017623 | ||
| 109 | Phosphorylation | AMLGLGDSSYPKFNY HHHCCCCCCCCCCCH | 27017623 | ||
| 110 | Phosphorylation | MLGLGDSSYPKFNYG HHCCCCCCCCCCCHH | 27017623 | ||
| 111 | Phosphorylation | LGLGDSSYPKFNYGI HCCCCCCCCCCCHHH | 27017623 | ||
| 238 | Phosphorylation | VNINKRITSEGHFQD EEECCCCCCCCCCCC | 27017623 | ||
| 239 | Phosphorylation | NINKRITSEGHFQDV EECCCCCCCCCCCCH | 27017623 | ||
| 535 | Phosphorylation | KGKIALHSSFSRDEE HCCEEEECCCCCCCC | 19823750 | ||
| 536 | Phosphorylation | GKIALHSSFSRDEEN CCEEEECCCCCCCCC | 19823750 | ||
| 538 | Phosphorylation | IALHSSFSRDEENSP EEEECCCCCCCCCCC | 19823750 | ||
| 544 | Phosphorylation | FSRDEENSPGVKYVQ CCCCCCCCCCHHHHH | 19823750 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of NDOR1_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of NDOR1_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of NDOR1_YEAST !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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