FIT2_YEAST - dbPTM
FIT2_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID FIT2_YEAST
UniProt AC Q08906
Protein Name Facilitator of iron transport 2
Gene Name FIT2
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 153
Subcellular Localization Secreted, cell wall . Membrane
Lipid-anchor, GPI-anchor . Covalently-linked GPI-modified cell wall protein (GPI-CWP).
Protein Description Involved in the uptake of non-siderophore and siderohpore sources of iron. Has a role in the retention of iron in the cell wall and periplasmic space..
Protein Sequence MKFSTIFGATTVMTAVSAAAVSSVMTTKTITATNGNNVYTKVVTDTADPIISYSTTRTVVVSNSDATYTKVVTEGPDTTSEKSTTKTLTLTNGSGSSTNLYTKTVTQAVESSTSSSSSSSSSSSSASSSGAAPAAFQGASVGALALGLISYLL
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
10PhosphorylationFSTIFGATTVMTAVS
HHHHCCHHHHHHHHH		21.9428132839
11PhosphorylationSTIFGATTVMTAVSA
HHHCCHHHHHHHHHH		14.0328132839
26PhosphorylationAAVSSVMTTKTITAT
HHHHCCCCCCEEEEE		24.0028132839
27PhosphorylationAVSSVMTTKTITATN
HHHCCCCCCEEEEEC		14.2228132839
92N-linked_GlycosylationTKTLTLTNGSGSSTN
EEEEEEECCCCCCCE		45.83-
96PhosphorylationTLTNGSGSSTNLYTK
EEECCCCCCCEEEEE		35.3728889911
97PhosphorylationLTNGSGSSTNLYTKT
EECCCCCCCEEEEEE		25.4927017623
130GPI-anchorSSSASSSGAAPAAFQ
CCCCCCCCCCCHHHC		27.92-
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of FIT2_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of FIT2_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of FIT2_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
PP2C4_YEASTPTC4genetic
27708008
SWC5_YEASTSWC5genetic
27708008
KCC4_YEASTKCC4genetic
27708008
YCZ2_YEASTYCR102Cgenetic
27708008
CAJ1_YEASTCAJ1genetic
27708008
CGR1_YEASTCGR1genetic
27708008
VAM7_YEASTVAM7genetic
27708008
TBP7_YEASTYTA7genetic
27708008
CSK21_YEASTCKA1genetic
27708008
DHOM_YEASTHOM6genetic
27708008
ACE2_YEASTACE2genetic
27708008
COQ11_YEASTYLR290Cgenetic
27708008
RL6B_YEASTRPL6Bgenetic
27708008
ZRC1_YEASTZRC1genetic
27708008
YBC9_YEASTYBL029Wgenetic
27708008
BMT2_YEASTBMT2genetic
27708008
HPC2_YEASTHPC2genetic
27708008
FRM2_YEASTFRM2genetic
27708008
MXR2_YEASTMXR2genetic
27708008
APA1_YEASTAPA1genetic
27708008
PEX34_YEASTPEX34genetic
27708008
VAC17_YEASTVAC17genetic
27708008
YIH1_YEASTYIH1genetic
27708008
YCY0_YEASTYCR090Cgenetic
27708008
SLX5_YEASTSLX5genetic
27708008
GPR1_YEASTGPR1genetic
27708008
PRM7_YEASTPRM7genetic
27708008
UGA3_YEASTUGA3genetic
27708008
RTR2_YEASTRTR2genetic
27708008
OCA6_YEASTOCA6genetic
27708008
TVP23_YEASTTVP23genetic
27708008
AFR1_YEASTAFR1genetic
27708008
TRS85_YEASTTRS85genetic
27708008
RM01_YEASTMRPL1genetic
27708008
RPA14_YEASTRPA14genetic
27708008
SAC3_YEASTSAC3genetic
27708008
CSN9_YEASTCSN9genetic
27708008
MNN10_YEASTMNN10genetic
27708008
MRX10_YEASTYDR282Cgenetic
27708008
DIT1_YEASTDIT1genetic
27708008
RMT2_YEASTRMT2genetic
27708008
SLX8_YEASTSLX8genetic
27708008
DDI1_YEASTDDI1genetic
27708008
CHAC_YEASTGCG1genetic
27708008
IES1_YEASTIES1genetic
27708008
YFH7_YEASTYFH7genetic
27708008
ERJ5_YEASTERJ5genetic
27708008
YGK1_YEASTYGL101Wgenetic
27708008
PHB2_YEASTPHB2genetic
27708008
LAM4_YEASTYHR080Cgenetic
27708008
RGI2_YEASTRGI2genetic
27708008
NIT1_YEASTNIT1genetic
27708008
PHO86_YEASTPHO86genetic
27708008
MRS3_YEASTMRS3genetic
27708008
SFH5_YEASTSFH5genetic
27708008
YJY1_YEASTYJR011Cgenetic
27708008
MTNB_YEASTMDE1genetic
27708008
RAD26_YEASTRAD26genetic
27708008
YJ85_YEASTYJR115Wgenetic
27708008
VPS24_YEASTVPS24genetic
27708008
AVT3_YEASTAVT3genetic
27708008
XPOT_YEASTLOS1genetic
27708008
IRS4_YEASTIRS4genetic
27708008
KTR2_YEASTKTR2genetic
27708008
APC9_YEASTAPC9genetic
27708008
YL179_YEASTYLR179Cgenetic
27708008
VTA1_YEASTVTA1genetic
27708008
UPS1_YEASTUPS1genetic
27708008
RS29A_YEASTRPS29Agenetic
27708008
TSA1_YEASTTSA1genetic
27708008
PYRE_YEASTURA5genetic
27708008
HXT2_YEASTHXT2genetic
27708008
TPP1_YEASTTPP1genetic
27708008
SPO1_YEASTSPO1genetic
27708008
COG5_YEASTCOG5genetic
27708008
FAR11_YEASTFAR11genetic
27708008
YO162_YEASTYOL162Wgenetic
27708008
RRP6_YEASTRRP6genetic
27708008
SUCA_YEASTLSC1genetic
27708008
PNS1_YEASTPNS1genetic
27708008
ODC2_YEASTODC2genetic
27708008
PMA2_YEASTPMA2genetic
27708008
YP071_YEASTYPL071Cgenetic
27708008
FMP30_YEASTFMP30genetic
27708008
SYH1_YEASTSYH1genetic
27708008
POC4_YEASTPOC4genetic
27708008
NIP80_YEASTNIP100genetic
27708008
SPEE_YEASTSPE3genetic
27708008
URN1_YEASTURN1genetic
27708008
HDA3_YEASTHDA3genetic
27708008
ATC1_YEASTPMR1genetic
29674565
INO2_YEASTINO2genetic
29674565
ERF3_YEASTSUP35genetic
29674565
KRE28_YEASTKRE28genetic
29674565
CEM1_YEASTCEM1genetic
29674565
FABG_YEASTOAR1genetic
29674565
CTF18_YEASTCTF18genetic
29674565
ERG2_YEASTERG2genetic
29674565
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of FIT2_YEAST

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Related Literatures of Post-Translational Modification
Phosphorylation
ReferencePubMed
"A multidimensional chromatography technology for in-depthphosphoproteome analysis.";
Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.;
Mol. Cell. Proteomics 7:1389-1396(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-96, AND MASSSPECTROMETRY.

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