USO1_MOUSE - dbPTM
USO1_MOUSE - PTM Information in dbPTM
Basic Information of Protein
UniProt ID USO1_MOUSE
UniProt AC Q9Z1Z0
Protein Name General vesicular transport factor p115
Gene Name Uso1
Organism Mus musculus (Mouse).
Sequence Length 959
Subcellular Localization Cytoplasm, cytosol. Golgi apparatus membrane
Peripheral membrane protein. Recycles between the cytosol and the Golgi apparatus during interphase..
Protein Description General vesicular transport factor required for intercisternal transport in the Golgi stack; it is required for transcytotic fusion and/or subsequent binding of the vesicles to the target membrane. May well act as a vesicular anchor by interacting with the target membrane and holding the vesicular and target membranes in proximity..
Protein Sequence MNFLRGVMGGQSAGPQHTEAETIQKLCDRVASSTLLDDRRNAVRALKSLSKKYRLEVGIQAMEHLIHVLQTDRSDSEIIAYALDTLYNIISNDEEEELEENSTRQSEDLGSQFTEIFIKQPENVTLLLSLLEEFDFHVRWPGVRLLTSLLKQLGPPVQQIILVSPMGVSRLMDLLADSREIIRNDGVLLLQALTRSNGAIQKIVAFENAFERLLDIITEEGNSDGGIVVEDCLILLQNLLKTNNSNQNFFKEGSYIQRMKPWFEVGEENSGWSAQKVTNLHLMLQLVRVLVSPTNPPGATSSCQKAMFQCGLLQQLCTILMATGIPADILTETINTVSEVIRGCQVNQDYFASVNAPSNPPRPAIVVLLMSMVNERQPFVLRCAVLYCFQCFLYKNEKGQGEIVATLLPSTIDATGNSVSAGQLLCGGLFSTDSLSNWCAAVALAHALQGNATQKEQLLRVQLATSIGNPPVSLLQQCTNILSQGSKIQTRVGLLMLLCTWLSNCPIAVTHFLHNSANVPFLTGQIAENLGEEEQLVQGLCALLLGISIYFNDNSLENYTKEKLKQLIEKRIGKENFIEKLGFISKHELYSRASQKPQPNFPSPEYMIFDHEFTKLVKELEGVITKAIYKSSEEDKKEEEVKKTLEQHDNIVTHYKNMIREQDLQLEELKQQVSTLKCQNEQLQTAVTQQASQIQQHKDQYNLLKVQLGKDNHHQGSHGDGAQVNGIQPEEISRLREEIEELKSQQALLQGQLAEKDSLIENLKSSQASGMSEQASATCPPRDPEQVAELKQELTALKSQLCSQSLEITRLQTENCELLQRAETLAKSVPVEGESEHVSAAKTTDVEGRLSALLQETKELKNEIKALSEERTAIQKQLDSSNSTIAILQTEKDKLDLEVTDSKKEQDDLLVLLADQDQKILSLKSKLKDLGHPVEEEDESGDQEDDDDEIDDGDKDQDI
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
25UbiquitinationTEAETIQKLCDRVAS
CHHHHHHHHHHHHHH		47.4322790023
47UbiquitinationRNAVRALKSLSKKYR
HHHHHHHHHHCHHHH		48.6527667366
50PhosphorylationVRALKSLSKKYRLEV
HHHHHHHCHHHHHHH		33.90-
106PhosphorylationEENSTRQSEDLGSQF
HHHCCCCCHHHHHHH		29.7728066266
111PhosphorylationRQSEDLGSQFTEIFI
CCCHHHHHHHHHHHH		29.4428066266
114PhosphorylationEDLGSQFTEIFIKQP
HHHHHHHHHHHHCCC		22.1228066266
147PhosphorylationWPGVRLLTSLLKQLG
CHHHHHHHHHHHHHC		23.1718779572
148PhosphorylationPGVRLLTSLLKQLGP
HHHHHHHHHHHHHCC		31.5118779572
202AcetylationRSNGAIQKIVAFENA
HCCCHHHHHHHHHHH		32.79-
202UbiquitinationRSNGAIQKIVAFENA
HCCCHHHHHHHHHHH		32.7922790023
301PhosphorylationTNPPGATSSCQKAMF
CCCCCCCHHHHHHHH		28.6918779572
303S-nitrosylationPPGATSSCQKAMFQC
CCCCCHHHHHHHHHH		4.8821278135
303S-nitrosocysteinePPGATSSCQKAMFQC
CCCCCHHHHHHHHHH		4.88-
303GlutathionylationPPGATSSCQKAMFQC
CCCCCHHHHHHHHHH		4.8824333276
565MalonylationNYTKEKLKQLIEKRI
CCCHHHHHHHHHHHH		54.8726320211
580UbiquitinationGKENFIEKLGFISKH
CCHHHHHHHCCCCHH		49.4422790023
580AcetylationGKENFIEKLGFISKH
CCHHHHHHHCCCCHH		49.4422826441
615AcetylationIFDHEFTKLVKELEG
EECHHHHHHHHHHHH		57.5123954790
626MalonylationELEGVITKAIYKSSE
HHHHHHHHHHHHCCH		22.9726320211
626AcetylationELEGVITKAIYKSSE
HHHHHHHHHHHHCCH		22.9723236377
626UbiquitinationELEGVITKAIYKSSE
HHHHHHHHHHHHCCH		22.97-
637UbiquitinationKSSEEDKKEEEVKKT
HCCHHHHHHHHHHHH		80.72-
642UbiquitinationDKKEEEVKKTLEQHD
HHHHHHHHHHHHHHH		43.23-
643UbiquitinationKKEEEVKKTLEQHDN
HHHHHHHHHHHHHHH		64.6122790023
655PhosphorylationHDNIVTHYKNMIREQ
HHHHHHHHHHHHHHH		8.49-
698UbiquitinationASQIQQHKDQYNLLK
HHHHHHCHHHHHEEE		42.0422790023
705UbiquitinationKDQYNLLKVQLGKDN
HHHHHEEEEECCCCC		30.9727667366
705MalonylationKDQYNLLKVQLGKDN
HHHHHEEEEECCCCC		30.9726320211
710UbiquitinationLLKVQLGKDNHHQGS
EEEEECCCCCCCCCC		65.0422790023
712UbiquitinationKVQLGKDNHHQGSHG
EEECCCCCCCCCCCC		37.7227667366
717PhosphorylationKDNHHQGSHGDGAQV
CCCCCCCCCCCCCCC		20.0923684622
733PhosphorylationGIQPEEISRLREEIE
CCCHHHHHHHHHHHH		28.6629109428
743UbiquitinationREEIEELKSQQALLQ
HHHHHHHHHHHHHHH		49.8822790023
744PhosphorylationEEIEELKSQQALLQG
HHHHHHHHHHHHHHH		39.9021659604
805PhosphorylationKSQLCSQSLEITRLQ
HHHHHHCCHHHHHHH		16.2129514104
816S-palmitoylationTRLQTENCELLQRAE
HHHHHHCHHHHHHHH		2.9528526873
816GlutathionylationTRLQTENCELLQRAE
HHHHHHCHHHHHHHH		2.9524333276
828PhosphorylationRAETLAKSVPVEGES
HHHHHHHCCCCCCCC		26.5030635358
828UbiquitinationRAETLAKSVPVEGES
HHHHHHHCCCCCCCC		26.5027667366
835UbiquitinationSVPVEGESEHVSAAK
CCCCCCCCCCCCCCH		43.8127667366
842UbiquitinationSEHVSAAKTTDVEGR
CCCCCCCHHCCHHHH		52.23-
842MalonylationSEHVSAAKTTDVEGR
CCCCCCCHHCCHHHH		52.2326320211
843UbiquitinationEHVSAAKTTDVEGRL
CCCCCCHHCCHHHHH		24.4127667366
850UbiquitinationTTDVEGRLSALLQET
HCCHHHHHHHHHHHH		5.3027667366
851PhosphorylationTDVEGRLSALLQETK
CCHHHHHHHHHHHHH		18.6029514104
858AcetylationSALLQETKELKNEIK
HHHHHHHHHHHHHHH		61.3723236377
861UbiquitinationLQETKELKNEIKALS
HHHHHHHHHHHHHHH		54.3427667366
868UbiquitinationKNEIKALSEERTAIQ
HHHHHHHHHHHHHHH		42.1227667366
876UbiquitinationEERTAIQKQLDSSNS
HHHHHHHHHHHCCCC		46.8722790023
883UbiquitinationKQLDSSNSTIAILQT
HHHHCCCCEEEEEEE		24.1227667366
894UbiquitinationILQTEKDKLDLEVTD
EEEEHHHHCCCEECC		55.7722790023
902PhosphorylationLDLEVTDSKKEQDDL
CCCEECCCCCHHCCE		35.9422807455
919UbiquitinationLLADQDQKILSLKSK
EEECCCHHHHHHHHH		54.6322790023
922PhosphorylationDQDQKILSLKSKLKD
CCCHHHHHHHHHHHH		36.9124719451
940PhosphorylationPVEEEDESGDQEDDD
CCCCCCCCCCCCCCC		61.0527087446
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of USO1_MOUSE !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of USO1_MOUSE !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of USO1_MOUSE !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
AP2A1_HUMANAP2A1physical
26496610
AP2B1_HUMANAP2B1physical
26496610
BMP1_HUMANBMP1physical
26496610
CO4A_HUMANC4Aphysical
26496610
CLCA_HUMANCLTAphysical
26496610
CLCB_HUMANCLTBphysical
26496610
CLH1_HUMANCLTCphysical
26496610
KC1A_HUMANCSNK1A1physical
26496610
KC1E_HUMANCSNK1Ephysical
26496610
GAK_HUMANGAKphysical
26496610
GALT2_HUMANGALNT2physical
26496610
GBB2_HUMANGNB2physical
26496610
GOGA2_HUMANGOLGA2physical
26496610
GOGA3_HUMANGOLGA3physical
26496610
LG3BP_HUMANLGALS3BPphysical
26496610
MYPT1_HUMANPPP1R12Aphysical
26496610
NP1L4_HUMANNAP1L4physical
26496610
NCBP1_HUMANNCBP1physical
26496610
P4HA1_HUMANP4HA1physical
26496610
PCM1_HUMANPCM1physical
26496610
P3C2A_HUMANPIK3C2Aphysical
26496610
PKP2_HUMANPKP2physical
26496610
KAPCA_HUMANPRKACAphysical
26496610
KAPCB_HUMANPRKACBphysical
26496610
KAP2_HUMANPRKAR2Aphysical
26496610
RBBP6_HUMANRBBP6physical
26496610
SEC13_HUMANSEC13physical
26496610
STX5_HUMANSTX5physical
26496610
SURF4_HUMANSURF4physical
26496610
TMOD1_HUMANTMOD1physical
26496610
TPM1_HUMANTPM1physical
26496610
TPM4_HUMANTPM4physical
26496610
ZFPL1_HUMANZFPL1physical
26496610
TBA1A_HUMANTUBA1Aphysical
26496610
CLH2_HUMANCLTCL1physical
26496610
GO45_HUMANBLZF1physical
26496610
TNK1_HUMANTNK1physical
26496610
LRRF2_HUMANLRRFIP2physical
26496610
GOSR1_HUMANGOSR1physical
26496610
SC22B_HUMANSEC22Bphysical
26496610
GOSR2_HUMANGOSR2physical
26496610
SC24C_HUMANSEC24Cphysical
26496610
EPN4_HUMANCLINT1physical
26496610
BCLF1_HUMANBCLAF1physical
26496610
TM9S4_HUMANTM9SF4physical
26496610
CE170_HUMANCEP170physical
26496610
SC16A_HUMANSEC16Aphysical
26496610
PDCD6_HUMANPDCD6physical
26496610
ABCF2_HUMANABCF2physical
26496610
ARPC2_HUMANARPC2physical
26496610
AKAP9_HUMANAKAP9physical
26496610
FARP1_HUMANFARP1physical
26496610
ACK1_HUMANTNK2physical
26496610
SC24B_HUMANSEC24Bphysical
26496610
RBM14_HUMANRBM14physical
26496610
YIF1A_HUMANYIF1Aphysical
26496610
TMEDA_HUMANTMED10physical
26496610
MA1B1_HUMANMAN1B1physical
26496610
BTBD3_HUMANBTBD3physical
26496610
CP131_HUMANCEP131physical
26496610
ENDD1_HUMANENDOD1physical
26496610
MPRIP_HUMANMPRIPphysical
26496610
CEP68_HUMANCEP68physical
26496610
F120A_HUMANFAM120Aphysical
26496610
SCFD1_HUMANSCFD1physical
26496610
UBR4_HUMANUBR4physical
26496610
CYTSA_HUMANSPECC1Lphysical
26496610
YIPF3_HUMANYIPF3physical
26496610
GORS2_HUMANGORASP2physical
26496610
MIPT3_HUMANTRAF3IP1physical
26496610
AP3M1_HUMANAP3M1physical
26496610
NPHP3_HUMANNPHP3physical
26496610
AT2C1_HUMANATP2C1physical
26496610
GOLI4_HUMANGOLIM4physical
26496610
TMOD3_HUMANTMOD3physical
26496610
UBIA1_HUMANUBIAD1physical
26496610
TMED7_HUMANTMED7physical
26496610
GOT1B_HUMANGOLT1Bphysical
26496610
GTSE1_HUMANGTSE1physical
26496610
SRRT_HUMANSRRTphysical
26496610
BMP2K_HUMANBMP2Kphysical
26496610
AMRA1_HUMANAMBRA1physical
26496610
ZNT6_HUMANSLC30A6physical
26496610
CEP72_HUMANCEP72physical
26496610
CK5P2_HUMANCDK5RAP2physical
26496610
BRE1A_HUMANRNF20physical
26496610
NCOA5_HUMANNCOA5physical
26496610
FBRS_HUMANFBRSphysical
26496610
ZN106_HUMANZNF106physical
26496610
INF2_HUMANINF2physical
26496610
GORS1_HUMANGORASP1physical
26496610
WNK1_HUMANWNK1physical
26496610
S35E1_HUMANSLC35E1physical
26496610
YIPF5_HUMANYIPF5physical
26496610
ACTL8_HUMANACTL8physical
26496610
LZTS2_HUMANLZTS2physical
26496610
STON2_HUMANSTON2physical
26496610
YIF1B_HUMANYIF1Bphysical
26496610
YTDC1_HUMANYTHDC1physical
26496610
GORAB_HUMANGORABphysical
26496610
UBX2A_HUMANUBXN2Aphysical
26496610
FA83B_HUMANFAM83Bphysical
26496610
RABL3_HUMANRABL3physical
26496610
FA83H_HUMANFAM83Hphysical
26496610
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of USO1_MOUSE

loading...

Related Literatures of Post-Translational Modification
Phosphorylation
ReferencePubMed
"Solid tumor proteome and phosphoproteome analysis by high resolutionmass spectrometry.";
Zanivan S., Gnad F., Wickstroem S.A., Geiger T., Macek B., Cox J.,Faessler R., Mann M.;
J. Proteome Res. 7:5314-5326(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-940, AND MASSSPECTROMETRY.

TOP
© 2024 Institute of Bioinformatics and Systems Biology, NYCU | Designed by : BiOmics Laboratory