| UniProt ID | STX11_HUMAN | |
|---|---|---|
| UniProt AC | O75558 | |
| Protein Name | Syntaxin-11 | |
| Gene Name | STX11 | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 287 | |
| Subcellular Localization |
Membrane Peripheral membrane protein . Golgi apparatus, trans-Golgi network membrane Peripheral membrane protein. |
|
| Protein Description | SNARE that acts to regulate protein transport between late endosomes and the trans-Golgi network.. | |
| Protein Sequence | MKDRLAELLDLSKQYDQQFPDGDDEFDSPHEDIVFETDHILESLYRDIRDIQDENQLLVADVKRLGKQNARFLTSMRRLSSIKRDTNSIAKAIKARGEVIHCKLRAMKELSEAAEAQHGPHSAVARISRAQYNALTLTFQRAMHDYNQAEMKQRDNCKIRIQRQLEIMGKEVSGDQIEDMFEQGKWDVFSENLLADVKGARAALNEIESRHRELLRLESRIRDVHELFLQMAVLVEKQADTLNVIELNVQKTVDYTGQAKAQVRKAVQYEEKNPCRTLCCFCCPCLK | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 74 | Phosphorylation | KQNARFLTSMRRLSS HHHHHHHHHHHHHHH | 20.12 | 23882029 | |
| 75 | Phosphorylation | QNARFLTSMRRLSSI HHHHHHHHHHHHHHC | 16.67 | 29970186 | |
| 80 | Phosphorylation | LTSMRRLSSIKRDTN HHHHHHHHHCCCCHH | 28.36 | 26055452 | |
| 81 | Phosphorylation | TSMRRLSSIKRDTNS HHHHHHHHCCCCHHH | 36.40 | 26055452 | |
| 88 | Phosphorylation | SIKRDTNSIAKAIKA HCCCCHHHHHHHHHH | 26.47 | - | |
| 103 | Ubiquitination | RGEVIHCKLRAMKEL HCCHHHHHHHHHHHH | 27.18 | 32015554 | |
| 173 | Phosphorylation | EIMGKEVSGDQIEDM HHHCCCCCHHHHHHH | 37.43 | 24719451 | |
| 190 | Phosphorylation | QGKWDVFSENLLADV CCCCCCCCCHHHHHH | 25.98 | 22817900 | |
| 241 | Phosphorylation | LVEKQADTLNVIELN HHHHCCCCCCEEEEE | 24.21 | 28060719 | |
| 260 | Ubiquitination | VDYTGQAKAQVRKAV ECCCCHHHHHHHHHH | 31.31 | 32015554 | |
| 279 | S-palmitoylation | KNPCRTLCCFCCPCL CCCCCEEEHHHCCCC | 1.33 | 24910990 | |
| 280 | S-palmitoylation | NPCRTLCCFCCPCLK CCCCEEEHHHCCCCC | 3.08 | 24910990 | |
| 282 | S-palmitoylation | CRTLCCFCCPCLK-- CCEEEHHHCCCCC-- | 1.26 | 24910990 | |
| 283 | S-palmitoylation | RTLCCFCCPCLK--- CEEEHHHCCCCC--- | 1.02 | 24910990 | |
| 285 | S-palmitoylation | LCCFCCPCLK----- EEHHHCCCCC----- | 4.76 | 24910990 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of STX11_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of STX11_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of STX11_HUMAN !! | ||||||
| Kegg Disease | ||||||
|---|---|---|---|---|---|---|
| H00109 | Familial hemophagocytic lymphohistiocytosis (FHPL), including the following three diseases: Perforin | |||||
| OMIM Disease | ||||||
| 603552 | Familial hemophagocytic lymphohistiocytosis 4 (FHL4) | |||||
| Kegg Drug | ||||||
| There are no disease associations of PTM sites. | ||||||
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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