CDR2_HUMAN - dbPTM
CDR2_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID CDR2_HUMAN
UniProt AC Q01850
Protein Name Cerebellar degeneration-related protein 2
Gene Name CDR2
Organism Homo sapiens (Human).
Sequence Length 454
Subcellular Localization
Protein Description
Protein Sequence MLAENLVEEFEMKEDEPWYDHQDLQQDLQLAAELGKTLLDRNTELEDSVQQMYTTNQEQLQEIEYLTKQVELLRQMNEQHAKVYEQLDVTARELEETNQKLVADSKASQQKILSLTETIECLQTNIDHLQSQVEELKSSGQGRRSPGKCDQEKPAPSFACLKELYDLRQHFVYDHVFAEKITSLQGQPSPDEEENEHLKKTVTMLQAQLSLERQKRVTMEEEYGLVLKENSELEQQLGATGAYRARALELEAEVAEMRQMLQSEHPFVNGVEKLVPDSLYVPFKEPSQSLLEEMFLTVPESHRKPLKRSSSETILSSLAGSDIVKGHEETCIRRAKAVKQRGISLLHEVDTQYSALKVKYEELLKKCQEEQDSLSHKAVQTSRAAAKDLTGVNAQSEPVASGWELASVNPEPVSSPTTPPEYKALFKEIFSCIKKTKQEIDEQRTKYRSLSSHS
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
53PhosphorylationEDSVQQMYTTNQEQL
HHHHHHHHHCCHHHH		13.1822817900
65PhosphorylationEQLQEIEYLTKQVEL
HHHHHHHHHHHHHHH		25.9027050516
67PhosphorylationLQEIEYLTKQVELLR
HHHHHHHHHHHHHHH		20.6627050516
84PhosphorylationNEQHAKVYEQLDVTA
HHHHHHHHHHHHCHH		9.3927642862
100UbiquitinationELEETNQKLVADSKA
HHHHHHHHHHHCCHH		47.1829967540
106UbiquitinationQKLVADSKASQQKIL
HHHHHCCHHHHHHHH		53.24-
131PhosphorylationTNIDHLQSQVEELKS
HHHHHHHHHHHHHHH		42.4222210691
138PhosphorylationSQVEELKSSGQGRRS
HHHHHHHHCCCCCCC		52.9426074081
139PhosphorylationQVEELKSSGQGRRSP
HHHHHHHCCCCCCCC		33.2826074081
145PhosphorylationSSGQGRRSPGKCDQE
HCCCCCCCCCCCCCC		36.3223401153
157PhosphorylationDQEKPAPSFACLKEL
CCCCCCCCHHHHHHH		27.8126074081
173PhosphorylationDLRQHFVYDHVFAEK
HHHHHHHHHHHHHHH		10.2125159151
180UbiquitinationYDHVFAEKITSLQGQ
HHHHHHHHHHHCCCC		48.1029967540
182PhosphorylationHVFAEKITSLQGQPS
HHHHHHHHHCCCCCC		34.1629978859
183PhosphorylationVFAEKITSLQGQPSP
HHHHHHHHCCCCCCC		23.3628102081
189PhosphorylationTSLQGQPSPDEEENE
HHCCCCCCCCHHHHH		36.7825850435
201PhosphorylationENEHLKKTVTMLQAQ
HHHHHHHHHHHHHHH		21.4421406692
203PhosphorylationEHLKKTVTMLQAQLS
HHHHHHHHHHHHHHH		19.8621406692
210PhosphorylationTMLQAQLSLERQKRV
HHHHHHHHHHHHHCC		18.9921406692
243PhosphorylationQLGATGAYRARALEL
HHCCCHHHHHHHHHH		13.22-
280PhosphorylationKLVPDSLYVPFKEPS
HCCCCCCCCCCCCCC		15.2725159151
287PhosphorylationYVPFKEPSQSLLEEM
CCCCCCCCHHHHHHH		33.2326074081
289PhosphorylationPFKEPSQSLLEEMFL
CCCCCCHHHHHHHCC		38.9826074081
309PhosphorylationHRKPLKRSSSETILS
HCCCCCCCCHHHHHH		36.3129255136
310PhosphorylationRKPLKRSSSETILSS
CCCCCCCCHHHHHHH		35.9129255136
311PhosphorylationKPLKRSSSETILSSL
CCCCCCCHHHHHHHH		39.7529255136
313PhosphorylationLKRSSSETILSSLAG
CCCCCHHHHHHHHCC		29.2129255136
316PhosphorylationSSSETILSSLAGSDI
CCHHHHHHHHCCCCH		21.3223927012
317PhosphorylationSSETILSSLAGSDIV
CHHHHHHHHCCCCHH		20.8523927012
321PhosphorylationILSSLAGSDIVKGHE
HHHHHCCCCHHCCCH		20.6823403867
344PhosphorylationAVKQRGISLLHEVDT
HHHHHCCCHHHHCHH		27.9229978859
353PhosphorylationLHEVDTQYSALKVKY
HHHCHHHHHHHHHHH		9.6727642862
354PhosphorylationHEVDTQYSALKVKYE
HHCHHHHHHHHHHHH		19.8024719451
377UbiquitinationEQDSLSHKAVQTSRA
HHHHHHHHHHHHHHH		47.0429967540
401PhosphorylationAQSEPVASGWELASV
CCCCCCCCCCEEEEC		44.6830108239
407PhosphorylationASGWELASVNPEPVS
CCCCEEEECCCCCCC		34.7430108239
414PhosphorylationSVNPEPVSSPTTPPE
ECCCCCCCCCCCCHH		41.1230108239
415PhosphorylationVNPEPVSSPTTPPEY
CCCCCCCCCCCCHHH		26.8830108239
417PhosphorylationPEPVSSPTTPPEYKA
CCCCCCCCCCHHHHH		54.6130108239
418PhosphorylationEPVSSPTTPPEYKAL
CCCCCCCCCHHHHHH		39.9830108239
422PhosphorylationSPTTPPEYKALFKEI
CCCCCHHHHHHHHHH		13.8230108239
431PhosphorylationALFKEIFSCIKKTKQ
HHHHHHHHHHHHHHH		22.1625159151
445PhosphorylationQEIDEQRTKYRSLSS
HHHHHHHHHHHHHCC		31.9325849741
449PhosphorylationEQRTKYRSLSSHS--
HHHHHHHHHCCCC--		29.5228102081
451PhosphorylationRTKYRSLSSHS----
HHHHHHHCCCC----		27.5328102081
452PhosphorylationTKYRSLSSHS-----
HHHHHHCCCC-----		32.8028102081
454PhosphorylationYRSLSSHS-------
HHHHCCCC-------		43.8128102081
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of CDR2_HUMAN !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of CDR2_HUMAN !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of CDR2_HUMAN !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
MYC_HUMANMYCphysical
10465786
CDR2_HUMANCDR2physical
10465786
MO4L2_HUMANMORF4L2physical
11988016
GMPPA_HUMANGMPPAphysical
21988832
COX5B_HUMANCOX5Bphysical
25416956
KIFC3_HUMANKIFC3physical
25416956
PKN1_HUMANPKN1physical
25416956
SMCE1_HUMANSMARCE1physical
25416956
TTHY_HUMANTTRphysical
25416956
IF4E2_HUMANEIF4E2physical
25416956
HDAC4_HUMANHDAC4physical
25416956
TMCC2_HUMANTMCC2physical
25416956
RM28_HUMANMRPL28physical
25416956
CHIC2_HUMANCHIC2physical
25416956
RSP14_HUMANRSPH14physical
25416956
AMOL2_HUMANAMOTL2physical
25416956
CCHCR_HUMANCCHCR1physical
25416956
NTAQ1_HUMANWDYHV1physical
25416956
TB22B_HUMANTBC1D22Bphysical
25416956
RCOR3_HUMANRCOR3physical
25416956
LIN37_HUMANLIN37physical
25416956
SH24A_HUMANSH2D4Aphysical
25416956
SCNM1_HUMANSCNM1physical
25416956
LENG1_HUMANLENG1physical
25416956
F110A_HUMANFAM110Aphysical
25416956
ENKD1_HUMANENKD1physical
25416956
F161A_HUMANFAM161Aphysical
25416956
TCHP_HUMANTCHPphysical
25416956
HAUS1_HUMANHAUS1physical
25416956
CA216_HUMANC1orf216physical
25416956
C2CD6_HUMANALS2CR11physical
25416956
TXLNA_HUMANTXLNAphysical
25416956
CD046_HUMANC4orf46physical
25416956
CC153_HUMANCCDC153physical
25416956
KANL1_HUMANKANSL1physical
25416956
CE57L_HUMANCEP57L1physical
25416956
F184A_HUMANFAM184Aphysical
28514442
CDR2L_HUMANCDR2Lphysical
28514442
STX1A_HUMANSTX1Aphysical
28514442
IGSF3_HUMANIGSF3physical
28514442
KTN1_HUMANKTN1physical
28514442
CD046_HUMANC4orf46physical
28514442
CCD18_HUMANCCDC18physical
28514442
STXB4_HUMANSTXBP4physical
28514442
PP2BC_HUMANPPP3CCphysical
28514442
DNA2_HUMANDNA2physical
28514442
SPA24_HUMANSPATA24physical
28514442
EP15R_HUMANEPS15L1physical
28514442
CANB1_HUMANPPP3R1physical
28514442
UQCC2_HUMANUQCC2physical
28514442
NEUL4_HUMANNEURL4physical
28514442
PP2BB_HUMANPPP3CBphysical
28514442
Drug and Disease Associations
Kegg Disease
There are no disease associations of PTM sites.
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of CDR2_HUMAN

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Related Literatures of Post-Translational Modification

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