dbPTM

RPIA_YEAST - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	RPIA_YEAST
UniProt AC	Q12189
Protein Name	Ribose-5-phosphate isomerase
Gene Name	RKI1
Organism	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length	258
Subcellular Localization
Protein Description
Protein Sequence	MAAGVPKIDALESLGNPLEDAKRAAAYRAVDENLKFDDHKIIGIGSGSTVVYVAERIGQYLHDPKFYEVASKFICIPTGFQSRNLILDNKLQLGSIEQYPRIDIAFDGADEVDENLQLIKGGGACLFQEKLVSTSAKTFIVVADSRKKSPKHLGKNWRQGVPIEIVPSSYVRVKNDLLEQLHAEKVDIRQGGSAKAGPVVTDNNNFIIDADFGEISDPRKLHREIKLLVGVVETGLFIDNASKAYFGNSDGSVEVTEK

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
22	Ubiquitination	GNPLEDAKRAAAYRA CCHHHHHHHHHHHHH	55.69	23749301
22	Acetylation	GNPLEDAKRAAAYRA CCHHHHHHHHHHHHH	55.69	24489116
65	Acetylation	GQYLHDPKFYEVASK HHHHHCHHHHHHHHH	67.64	24489116
90	Acetylation	RNLILDNKLQLGSIE CCEEECCCCCCCCHH	36.96	24489116
185	Acetylation	LEQLHAEKVDIRQGG HHHHHHHCCCCCCCC	46.09	24489116

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of RPIA_YEAST !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of RPIA_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of RPIA_YEAST !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
TBCA_YEAST	RBL2	physical	9914379
RPIA_YEAST	RKI1	physical	16054529
RPIA_YEAST	RKI1	physical	18467557
RPIA_YEAST	RKI1	physical	18719252
FUMH_YEAST	FUM1	genetic	21623372
CYS3_YEAST	CYS3	genetic	21623372
EPT1_YEAST	EPT1	genetic	21623372
PDX3_YEAST	PDX3	genetic	21623372
PPT2_YEAST	PPT2	genetic	21623372
THDH_YEAST	ILV1	genetic	21623372
XPT1_YEAST	XPT1	genetic	21623372
DHOM_YEAST	HOM6	genetic	21623372
HTD2_YEAST	HTD2	genetic	21623372
ERG2_YEAST	ERG2	genetic	21623372
ADH3_YEAST	ADH3	genetic	21623372
COQ4_YEAST	COQ4	genetic	21623372
ATPO_YEAST	ATP5	genetic	21623372
CDC53_YEAST	CDC53	genetic	27708008
RSP5_YEAST	RSP5	genetic	27708008
MET30_YEAST	MET30	genetic	27708008
ATC7_YEAST	NEO1	genetic	27708008
ARPC5_YEAST	ARC15	genetic	27708008
NU159_YEAST	NUP159	genetic	27708008
MOT1_YEAST	MOT1	genetic	27708008
CTK1_YEAST	CTK1	genetic	27708008
GCN1_YEAST	GCN1	genetic	27708008
STU1_YEAST	STU1	genetic	27708008
DPOA2_YEAST	POL12	genetic	27708008
CALM_YEAST	CMD1	genetic	27708008
CKS1_YEAST	CKS1	genetic	27708008
TRS20_YEAST	TRS20	genetic	27708008
SCC1_YEAST	MCD1	genetic	27708008
APC11_YEAST	APC11	genetic	27708008
RPN6_YEAST	RPN6	genetic	27708008
CDC48_YEAST	CDC48	genetic	27708008
SNU56_YEAST	SNU56	genetic	27708008
TRS23_YEAST	TRS23	genetic	27708008
RPB7_YEAST	RPB7	genetic	27708008
SMT3_YEAST	SMT3	genetic	27708008
COG3_YEAST	COG3	genetic	27708008
MOB2_YEAST	MOB2	genetic	27708008
CDC20_YEAST	CDC20	genetic	27708008
MCE1_YEAST	CEG1	genetic	27708008
SMD1_YEAST	SMD1	genetic	27708008
ESP1_YEAST	ESP1	genetic	27708008
DAM1_YEAST	DAM1	genetic	27708008
CBF3A_YEAST	CBF2	genetic	27708008
BRL1_YEAST	BRL1	genetic	27708008
RFC2_YEAST	RFC2	genetic	27708008
BET3_YEAST	BET3	genetic	27708008
GPI13_YEAST	GPI13	genetic	27708008
SED5_YEAST	SED5	genetic	27708008
BOS1_YEAST	BOS1	genetic	27708008
SPC24_YEAST	SPC24	genetic	27708008
VTI1_YEAST	VTI1	genetic	27708008
CAP_YEAST	SRV2	genetic	27708008
TPT1_YEAST	TPT1	genetic	27708008
PSA7_YEAST	PRE10	genetic	27708008
PSB5_YEAST	PRE2	genetic	27708008
DAL81_YEAST	DAL81	genetic	27708008
SAC1_YEAST	SAC1	genetic	27708008
SST2_YEAST	SST2	genetic	27708008
HRB1_YEAST	HRB1	genetic	27708008
KPR4_YEAST	PRS4	genetic	27708008
ICS2_YEAST	ICS2	genetic	27708008
SGF29_YEAST	SGF29	genetic	27708008
PAT1_YEAST	PAT1	genetic	27708008
OCA4_YEAST	OCA4	genetic	27708008
PP2C1_YEAST	PTC1	genetic	27708008
BAP3_YEAST	BAP3	genetic	27708008
VPS41_YEAST	VPS41	genetic	27708008
SAC3_YEAST	SAC3	genetic	27708008
AIM11_YEAST	AIM11	genetic	27708008
SA155_YEAST	SAP155	genetic	27708008
ATC1_YEAST	PMR1	genetic	27708008
HUR1_YEAST	HUR1	genetic	27708008
VAM7_YEAST	VAM7	genetic	27708008
YG1X_YEAST	YGR050C	genetic	27708008
INM1_YEAST	INM1	genetic	27708008
RPA34_YEAST	RPA34	genetic	27708008
CSN12_YEAST	YJR084W	genetic	27708008
UBR2_YEAST	UBR2	genetic	27708008
APTH1_YEAST	YLR118C	genetic	27708008
TOP3_YEAST	TOP3	genetic	27708008
MAS5_YEAST	YDJ1	genetic	27708008
INO4_YEAST	INO4	genetic	27708008
RAD1_YEAST	RAD1	genetic	27708008
RU2A_YEAST	LEA1	genetic	27708008
YP022_YEAST	YPR022C	genetic	27708008

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of RPIA_YEAST

Related Literatures of Post-Translational Modification