TF3A_YEAST - dbPTM
TF3A_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID TF3A_YEAST
UniProt AC P39933
Protein Name Transcription factor IIIA
Gene Name PZF1
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 429
Subcellular Localization Nucleus.
Protein Description Interacts with the internal control region (ICR) of approximately 50 bases within the 5S RNA genes, is required for correct transcription of these genes by RNA polymerase III. Also binds the transcribed 5S RNA's..
Protein Sequence MGGEVLNNEGMPLAELKQETIPISRSESSESLNSLTSTRSSSSNRPKTYFCDYDGCDKAFTRPSILTEHQLSVHQGLRAFQCDKCAKSFVKKSHLERHLYTHSDTKPFQCSYCGKGVTTRQQLKRHEVTHTKSFICPEEGCNLRFYKHPQLRAHILSVHLHKLTCPHCNKSFQRPYRLRNHISKHHDPEVENPYQCTFAGCCKEFRIWSQLQSHIKNDHPKLKCPICSKPCVGENGLQMHMIIHDDSLVTKNWKCHICPDMSFSRKHDLLTHYGSIHTEEDIPLELKYKISDIQQLVQDHGVQLGNSKHSNEQDEEKISNRLRKRRKLTENNNVEFLQNEVDLEKRLESGENGLNLLLNTVGRKYRCFYNNCSRTFKTKEKYEKHIDKHKVHELKLKILQEKEENKTLVDQNHKEPFIIQKETQSAGDK
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
20PhosphorylationLAELKQETIPISRSE
HHHHCCCCCCCCCCC		29.5628889911
24PhosphorylationKQETIPISRSESSES
CCCCCCCCCCCCCHH		25.1328889911
28PhosphorylationIPISRSESSESLNSL
CCCCCCCCCHHHHHH		40.4228889911
291PhosphorylationLELKYKISDIQQLVQ
CEEEEEHHHHHHHHH		25.2230377154
349PhosphorylationDLEKRLESGENGLNL
CHHHHHHHCCHHHHH		56.8730377154
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of TF3A_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of TF3A_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of TF3A_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
ASF1_YEASTASF1genetic
17314980
CDC26_YEASTCDC26genetic
17314980
RAD5_YEASTRAD5genetic
17314980
SNF1_YEASTSNF1genetic
17314980
LIS1_YEASTPAC1genetic
17314980
AAKG_YEASTSNF4genetic
17314980
COG8_YEASTCOG8genetic
17314980
LEO1_YEASTLEO1genetic
17314980
CIN1_YEASTCIN1genetic
17314980
SQS1_YEASTSQS1genetic
17314980
IES2_YEASTIES2genetic
17314980
CCS1_YEASTCCS1genetic
17314980
PHO23_YEASTPHO23genetic
17314980
SUR1_YEASTSUR1genetic
17314980
SET3_YEASTSET3genetic
17314980
ATC6_YEASTSPF1genetic
17314980
RSC2_YEASTRSC2genetic
17314980
SCC1_YEASTMCD1genetic
27708008
LIP1_YEASTLIP1genetic
27708008
SWR1_YEASTSWR1genetic
27708008
CND2_YEASTBRN1genetic
27708008
CKS1_YEASTCKS1genetic
27708008
NOP14_YEASTNOP14genetic
27708008
RRP45_YEASTRRP45genetic
27708008
CND3_YEASTYCG1genetic
27708008
TFC6_YEASTTFC6genetic
27708008
UTP6_YEASTUTP6genetic
27708008
PRP3_YEASTPRP3genetic
27708008
CDC4_YEASTCDC4genetic
27708008
MOB2_YEASTMOB2genetic
27708008
CDC14_YEASTCDC14genetic
27708008
SLD3_YEASTSLD3genetic
27708008
SWC4_YEASTSWC4genetic
27708008
RRP41_YEASTSKI6genetic
27708008
MED6_YEASTMED6genetic
27708008
RPC9_YEASTRPC17genetic
27708008
MTR4_YEASTMTR4genetic
27708008
DPB11_YEASTDPB11genetic
27708008
GWT1_YEASTGWT1genetic
27708008
ESS1_YEASTESS1genetic
27708008
CDC11_YEASTCDC11genetic
27708008
GRC3_YEASTGRC3genetic
27708008
SDO1_YEASTSDO1genetic
27708008
SEC22_YEASTSEC22genetic
27708008
MCM5_YEASTMCM5genetic
27708008
RU1C_YEASTYHC1genetic
27708008
SEN1_YEASTSEN1genetic
27708008
NOP2_YEASTNOP2genetic
27708008
PRP2_YEASTPRP2genetic
27708008
DBP6_YEASTDBP6genetic
27708008
RRP44_YEASTDIS3genetic
27708008
RIB2_YEASTRIB2genetic
27708008
RPC1_YEASTRPO31genetic
27708008
ESA1_YEASTESA1genetic
27708008
TFC8_YEASTTFC8genetic
27708008
TBF1_YEASTTBF1genetic
27708008
FUN30_YEASTFUN30genetic
27708008
SHE1_YEASTSHE1genetic
27708008
H4_YEASTHHF1genetic
27708008
NPL4_YEASTNPL4genetic
27708008
STE50_YEASTSTE50genetic
27708008
MRC1_YEASTMRC1genetic
27708008
MBP1_YEASTMBP1genetic
27708008
VMS1_YEASTVMS1genetic
27708008
ESC2_YEASTESC2genetic
27708008
STP1_YEASTSTP1genetic
27708008
BLM10_YEASTBLM10genetic
27708008
XRN1_YEASTXRN1genetic
27708008
ATG1_YEASTATG1genetic
27708008
LRP1_YEASTLRP1genetic
27708008
DAL81_YEASTDAL81genetic
27708008
RAV1_YEASTRAV1genetic
27708008
YJ24_YEASTKCH1genetic
27708008
DOHH_YEASTLIA1genetic
27708008
MPCP_YEASTMIR1genetic
27708008
MUD2_YEASTMUD2genetic
27708008
UTH1_YEASTUTH1genetic
27708008
RL22A_YEASTRPL22Agenetic
27708008
TOP3_YEASTTOP3genetic
27708008
VIP1_YEASTVIP1genetic
27708008
TMA23_YEASTTMA23genetic
27708008
NOP12_YEASTNOP12genetic
27708008
RRP6_YEASTRRP6genetic
27708008
CSK22_YEASTCKA2genetic
27708008
PTP2_YEASTPTP2genetic
27708008
RMI1_YEASTRMI1genetic
27708008
YP034_YEASTYPL034Wgenetic
27708008
ELOC_YEASTELC1genetic
27708008
TGS1_YEASTTGS1genetic
27708008
NCBP2_YEASTCBC2genetic
27708008
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of TF3A_YEAST

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Related Literatures of Post-Translational Modification
Phosphorylation
ReferencePubMed
"A multidimensional chromatography technology for in-depthphosphoproteome analysis.";
Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.;
Mol. Cell. Proteomics 7:1389-1396(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-28, AND MASSSPECTROMETRY.

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