GPR21_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: GPR21_HUMAN
• UniProt AC: Q99679
• Protein Name: Probable G-protein coupled receptor 21
• Gene Name: GPR21
• Organism: Homo sapiens (Human).
• Sequence Length: 349
• Subcellular Localization: Cell membrane; Multi-pass membrane protein.
• Protein Description: Orphan receptor..
• Protein Sequence: MNSTLDGNQSSHPFCLLAFGYLETVNFCLLEVLIIVFLTVLIISGNIIVIFVFHCAPLLNHHTTSYFIQTMAYADLFVGVSCVVPSLSLLHHPLPVEESLTCQIFGFVVSVLKSVSMASLACISIDRYIAITKPLTYNTLVTPWRLRLCIFLIWLYSTLVFLPSFFHWGKPGYHGDVFQWCAESWHTDSYFTLFIVMMLYAPAALIVCFTYFNIFRICQQHTKDISERQARFSSQSGETGEVQACPDKRYAMVLFRITSVFYILWLPYIIYFLLESSTGHSNRFASFLTTWLAISNSFCNCVIYSLSNSVFQRGLKRLSGAMCTSCASQTTANDPYTVRSKGPLNGCHI

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	N-linked_Glycosylation	------MNSTLDGNQ ------CCCCCCCCC	43.64	UniProtKB CARBOHYD
8	N-linked_Glycosylation	MNSTLDGNQSSHPFC CCCCCCCCCCCCHHH	37.92	UniProtKB CARBOHYD
128	Phosphorylation	ACISIDRYIAITKPL HHHCCCCEEEECCCC	7.31	22817900
281	Phosphorylation	LESSTGHSNRFASFL HHCCCCCCHHHHHHH	30.92	-
319	Phosphorylation	QRGLKRLSGAMCTSC HHHHHHHHCCEECCC	28.65	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of GPR21_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of GPR21_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of GPR21_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
MARH6_HUMAN	MARCH6	physical	28514442
ERMP1_HUMAN	ERMP1	physical	28514442
OTU6A_HUMAN	OTUD6A	physical	28514442
S1PR5_HUMAN	S1PR5	physical	28514442
FZD3_HUMAN	FZD3	physical	28514442
SIDT2_HUMAN	SIDT2	physical	28514442
ZDHC5_HUMAN	ZDHHC5	physical	28514442
SC6A6_HUMAN	SLC6A6	physical	28514442
S15A4_HUMAN	SLC15A4	physical	28514442
S47A1_HUMAN	SLC47A1	physical	28514442
ADCY9_HUMAN	ADCY9	physical	28514442
FZD2_HUMAN	FZD2	physical	28514442
EDA_HUMAN	EDA	physical	28514442
CNNM1_HUMAN	CNNM1	physical	28514442
VEZA_HUMAN	VEZT	physical	28514442
UBB_HUMAN	UBB	physical	28514442
S12A9_HUMAN	SLC12A9	physical	28514442
AT11C_HUMAN	ATP11C	physical	28514442
PIGN_HUMAN	PIGN	physical	28514442
S12A6_HUMAN	SLC12A6	physical	28514442
PTN1_HUMAN	PTPN1	physical	28514442
ATPB_HUMAN	ATP5B	physical	28514442
HSDL1_HUMAN	HSDL1	physical	28514442
ANO6_HUMAN	ANO6	physical	28514442
FADS1_HUMAN	FADS1	physical	28514442
T120B_HUMAN	TMEM120B	physical	28514442
BT2A2_HUMAN	BTN2A2	physical	28514442
FACE1_HUMAN	ZMPSTE24	physical	28514442
S19A2_HUMAN	SLC19A2	physical	28514442
ZDHC9_HUMAN	ZDHHC9	physical	28514442
B3A2_HUMAN	SLC4A2	physical	28514442
TSN3_HUMAN	TSPAN3	physical	28514442
LPAR1_HUMAN	LPAR1	physical	28514442
CTGE5_HUMAN	CTAGE5	physical	28514442
ELOV2_HUMAN	ELOVL2	physical	28514442
ATP8_HUMAN	ATP8	physical	28514442
AT5F1_HUMAN	ATP5F1	physical	28514442
S12A4_HUMAN	SLC12A4	physical	28514442
TCEA1_HUMAN	TCEA1	physical	28514442
F189B_HUMAN	FAM189B	physical	28514442
S12A7_HUMAN	SLC12A7	physical	28514442
T184B_HUMAN	TMEM184B	physical	28514442
S29A1_HUMAN	SLC29A1	physical	28514442
RHBD3_HUMAN	RHBDD3	physical	28514442
ST7_HUMAN	ST7	physical	28514442
RETR3_HUMAN	FAM134C	physical	28514442
LMBR1_HUMAN	LMBR1	physical	28514442
TOM34_HUMAN	TOMM34	physical	28514442
SG196_HUMAN	POMK	physical	28514442
EBP_HUMAN	EBP	physical	28514442
FITM2_HUMAN	FITM2	physical	28514442
CIA30_HUMAN	NDUFAF1	physical	28514442
AGRL1_HUMAN	LPHN1	physical	28514442
MBOA7_HUMAN	MBOAT7	physical	28514442
TM164_HUMAN	TMEM164	physical	28514442
TXD15_HUMAN	TXNDC15	physical	28514442
CXA1_HUMAN	GJA1	physical	28514442
TMM56_HUMAN	TMEM56	physical	28514442
LGR4_HUMAN	LGR4	physical	28514442
LCLT1_HUMAN	LCLAT1	physical	28514442
CSCL2_HUMAN	TMEM63B	physical	28514442
MBRL_HUMAN	TMEM259	physical	28514442
FZD5_HUMAN	FZD5	physical	28514442
GP1BB_HUMAN	GP1BB	physical	28514442
ATP5L_HUMAN	ATP5L	physical	28514442
T179B_HUMAN	TMEM179B	physical	28514442
CERS6_HUMAN	CERS6	physical	28514442
PTH2_HUMAN	PTRH2	physical	28514442
MFSD8_HUMAN	MFSD8	physical	28514442
KCNJ8_HUMAN	KCNJ8	physical	28514442
DGAT1_HUMAN	DGAT1	physical	28514442

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.