CNNM1_HUMAN - dbPTM
CNNM1_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID CNNM1_HUMAN
UniProt AC Q9NRU3
Protein Name Metal transporter CNNM1
Gene Name CNNM1
Organism Homo sapiens (Human).
Sequence Length 951
Subcellular Localization Cell membrane
Multi-pass membrane protein.
Protein Description Probable metal transporter..
Protein Sequence MAAAAAAAAAVGVRLRDCCSRGAVLLLFFSLSPRPPAAAAWLLGLRPEDTAGGRVSLEGGTLRAAEGTSFLLRVYFQPGPPATAAPVPSPTLNSGENGTGDWAPRLVFIEEPPGGGGVAPSAVPTRPPGPQRCREQSDWASDVEVLGPLRPGGVAGSALVQVRVRELRKGEAERGGAGGGGKLFSLCAWDGRAWHHHGAAGGFLLRVRPRLYGPGGDLLPPAWLRALGALLLLALSALFSGLRLSLLSLDPVELRVLRNSGSAAEQEQARRVQAVRGRGTHLLCTLLLGQAGANAALAGWLYTSLPPGFGGTGEDYSEEGIHFPWLPALVCTGAVFLGAEICPYSVCSRHGLAIASHSVCLTRLLMAAAFPVCYPLGRLLDWALRQEISTFYTREKLLETLRAADPYSDLVKEELNIIQGALELRTKVVEEVLTPLGDCFMLRSDAVLDFATVSEILRSGYTRIPVYEGDQRHNIVDILFVKDLAFVDPDDCTPLLTVTRFYNRPLHCVFNDTRLDTVLEEFKKGKSHLAIVQRVNNEGEGDPFYEVMGIVTLEDIIEEIIKSEILDETDLYTDNRKKQRVPQRERKRHDFSLFKLSDTEMRVKISPQLLLATHRFMATEVEPFKSLYLSEKILLRLLKHPNVIQELKFDEKNKKAPEHYLYQRNRPVDYFVLLLQGKVEVEVGKEGLRFENGAFTYYGVPAIMTTACSDNDVRKVGSLAGSSVFLNRSPSRCSGLNRSESPNRERSDFGGSNTQLYSSSNNLYMPDYSVHILSDVQFVKITRQQYQNALTACHMDSSPQSPDMEAFTDGDSTKAPTTRGTPQTPKDDPAITLLNNRNSLPCSRSDGLRSPSEVVYLRMEELAFTQEEMTDFEEHSTQQLTLSPAAVPTRAASDSECCNINLDTETSPCSSDFEENVGKKLLRTLSGQKRKRSPEGERTSEDNSNLTPLIT
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
30PhosphorylationAVLLLFFSLSPRPPA
CCEEEEEECCCCCHH		22.1724719451
32PhosphorylationLLLFFSLSPRPPAAA
EEEEEECCCCCHHHH		20.0524719451
69PhosphorylationLRAAEGTSFLLRVYF
EEEEECCEEEEEEEE		25.4224719451
212PhosphorylationLRVRPRLYGPGGDLL
EEECCCCCCCCCCCC		23.6620049867
362PhosphorylationASHSVCLTRLLMAAA
HCHHHHHHHHHHHHH		17.72-
389PhosphorylationWALRQEISTFYTREK
HHHHHHHHHHHCHHH		16.2324043423
390PhosphorylationALRQEISTFYTREKL
HHHHHHHHHHCHHHH		26.7324043423
392PhosphorylationRQEISTFYTREKLLE
HHHHHHHHCHHHHHH		12.6524043423
393PhosphorylationQEISTFYTREKLLET
HHHHHHHCHHHHHHH		28.3224043423
407PhosphorylationTLRAADPYSDLVKEE
HHHHCCCCHHHHHHH		18.50-
444PhosphorylationGDCFMLRSDAVLDFA
CCCEEECCCCCCCHH		26.4327251275
526UbiquitinationLEEFKKGKSHLAIVQ
HHHHHCCCCEEEEEE		43.51-
569PhosphorylationKSEILDETDLYTDNR
HCCCCCCCCCCCCCH		30.8529978859
572PhosphorylationILDETDLYTDNRKKQ
CCCCCCCCCCCHHHC		18.1728796482
573PhosphorylationLDETDLYTDNRKKQR
CCCCCCCCCCHHHCC		33.8128796482
592PhosphorylationERKRHDFSLFKLSDT
HHHHCCCCEEECCCC		38.6724719451
660PhosphorylationNKKAPEHYLYQRNRP
CCCCCCHHHCCCCCC		12.87-
722PhosphorylationKVGSLAGSSVFLNRS
HHHHHCCCCCCCCCC		20.0927732954
723PhosphorylationVGSLAGSSVFLNRSP
HHHHCCCCCCCCCCH		18.9027732954
729PhosphorylationSSVFLNRSPSRCSGL
CCCCCCCCHHHCCCC		26.5919060867
731PhosphorylationVFLNRSPSRCSGLNR
CCCCCCHHHCCCCCC		47.3628302921
741PhosphorylationSGLNRSESPNRERSD
CCCCCCCCCCCCCCC		28.81-
786PhosphorylationVKITRQQYQNALTAC
EECCHHHHHHHHHHH		8.7328122231
791PhosphorylationQQYQNALTACHMDSS
HHHHHHHHHHCCCCC		25.4828122231
797PhosphorylationLTACHMDSSPQSPDM
HHHHCCCCCCCCCCC		36.0228122231
798PhosphorylationTACHMDSSPQSPDME
HHHCCCCCCCCCCCC		23.7728122231
801PhosphorylationHMDSSPQSPDMEAFT
CCCCCCCCCCCCCCC		26.6728122231
808PhosphorylationSPDMEAFTDGDSTKA
CCCCCCCCCCCCCCC		46.2328122231
812PhosphorylationEAFTDGDSTKAPTTR
CCCCCCCCCCCCCCC		37.0228122231
813PhosphorylationAFTDGDSTKAPTTRG
CCCCCCCCCCCCCCC		35.6528122231
821PhosphorylationKAPTTRGTPQTPKDD
CCCCCCCCCCCCCCC		14.6626471730
824PhosphorylationTTRGTPQTPKDDPAI
CCCCCCCCCCCCCCE		33.2426471730
832PhosphorylationPKDDPAITLLNNRNS
CCCCCCEEECCCCCC		27.5726471730
839PhosphorylationTLLNNRNSLPCSRSD
EECCCCCCCCCCCCC		30.3729414761
843PhosphorylationNRNSLPCSRSDGLRS
CCCCCCCCCCCCCCC		32.6426471730
845PhosphorylationNSLPCSRSDGLRSPS
CCCCCCCCCCCCCHH		21.5324076635
850PhosphorylationSRSDGLRSPSEVVYL
CCCCCCCCHHHEEEE		37.5126471730
852PhosphorylationSDGLRSPSEVVYLRM
CCCCCCHHHEEEEEH		44.2426471730
856PhosphorylationRSPSEVVYLRMEELA
CCHHHEEEEEHHHHH		8.1827259358
926PhosphorylationKKLLRTLSGQKRKRS
HHHHHHHHCCCCCCC		38.2724719451
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of CNNM1_HUMAN !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of CNNM1_HUMAN !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of CNNM1_HUMAN !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of CNNM1_HUMAN !!
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of CNNM1_HUMAN

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Related Literatures of Post-Translational Modification

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