| UniProt ID | YM11_YEAST | |
|---|---|---|
| UniProt AC | P39523 | |
| Protein Name | Uncharacterized protein YMR124W | |
| Gene Name | YMR124W | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 943 | |
| Subcellular Localization | ||
| Protein Description | ||
| Protein Sequence | MDAGLSTMATRNGQSSARVKLRNNLLNNDIGNIDIRDETPISRNGNDSNINIQPSSVPQQQQQQQQYYRNGMNEAPIQAPLQQRQIPMQNYSQQQRQQQQYNFEYSNPHMNEIPLMQHNFTKPSLSNNRDNVNGKKASSFTQSSFSNFFKHKHQFGKSKKNTKGTGGGGDGDDDDEVILDDSANSDLTFNDIQTFGHKGGDKYGYGGDSTPIIPTLVTKDRGNMSNTEYRKYITNQRKTAMNAMAKQTKNGTLASLPPRAMSLQSFPNGNPLMQAPTPHPRFQPNKMVSANYSRSNSLMSGPPGQFRQPQQQRMLPMNNYNNHPGQFQNTPPVMPSGQQPPQQPRTLSLTNGPRYSPQNPRPFAGHQQISQRQQQQQQQLQLHPMSEGYRTMSLQSQNVPQGFNPWSPNDNDRKAVSMKQPISQSSISSKNNSAYSIPNVQNNSLTTFSPSSPTDATAMPNSTKQGSSPLKKQVNIDQPIENKGKLNVLQLSTPQQNELKEKERKLAEMEKSLREREALVEEKEKERAEKNTEANEEEEISHESDDLNLRPASALETGLKDLKLESESAVANRASLSTFSSTFSDSPSKQRIINTRTGMYKLENSTDINEYVTAQEFPSPGKYNSNSDNGEMNTTNEVDFDFNTSKRASLLQSIPERDPKRNVSDATIKRRESDGNGRRLSNVNISMNQENINNDTFLYKKNNRDGHLSAVSHMSSSSRRSFISNTLPLNIDSASESDNFVPHMDGSPSKTKSAPVSYDKDGMNASEEDFSFDNTLAKPYEPLYARRGDITSAGSTSGEDSSQPKMITISGEQLNLITENKELMNELTLVSTELAESIKRETELEERIRLYETNNSAPSFDDSSSVSFSDFEKELRKKSSKIVQLIQQLNDERLKRFIAEEQLLLQENGTKPSSMELVGRIENLNKLIDERDSEIEMLKGRLQ | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
|
|
||
* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 1 | Acetylation | -------MDAGLSTM -------CCCCHHCC | 7.81 | 22814378 | |
| 39 | Phosphorylation | NIDIRDETPISRNGN CCCCCCCCCCCCCCC | 30.16 | 28889911 | |
| 48 | Phosphorylation | ISRNGNDSNINIQPS CCCCCCCCCCCCCCC | 43.54 | 21440633 | |
| 138 | Phosphorylation | NVNGKKASSFTQSSF CCCCCCCHHHCHHHH | 34.56 | 22890988 | |
| 139 | Phosphorylation | VNGKKASSFTQSSFS CCCCCCHHHCHHHHH | 36.85 | 22369663 | |
| 141 | Phosphorylation | GKKASSFTQSSFSNF CCCCHHHCHHHHHHH | 29.50 | 22890988 | |
| 143 | Phosphorylation | KASSFTQSSFSNFFK CCHHHCHHHHHHHHH | 30.23 | 22890988 | |
| 144 | Phosphorylation | ASSFTQSSFSNFFKH CHHHCHHHHHHHHHH | 23.91 | 21440633 | |
| 150 | Acetylation | SSFSNFFKHKHQFGK HHHHHHHHHHHHCCC | 47.83 | 24489116 | |
| 185 | Phosphorylation | ILDDSANSDLTFNDI EECCCCCCCCCHHHH | 33.44 | 24961812 | |
| 188 | Phosphorylation | DSANSDLTFNDIQTF CCCCCCCCHHHHHCC | 25.94 | 24961812 | |
| 203 | Phosphorylation | GHKGGDKYGYGGDST CCCCCCCCCCCCCCC | 21.96 | 24961812 | |
| 205 | Phosphorylation | KGGDKYGYGGDSTPI CCCCCCCCCCCCCCC | 18.16 | 24961812 | |
| 209 | Phosphorylation | KYGYGGDSTPIIPTL CCCCCCCCCCCCCEE | 39.08 | 21551504 | |
| 210 | Phosphorylation | YGYGGDSTPIIPTLV CCCCCCCCCCCCEEE | 24.21 | 21440633 | |
| 215 | Phosphorylation | DSTPIIPTLVTKDRG CCCCCCCEEEECCCC | 24.37 | 24961812 | |
| 218 | Phosphorylation | PIIPTLVTKDRGNMS CCCCEEEECCCCCCC | 30.27 | 27017623 | |
| 219 | Acetylation | IIPTLVTKDRGNMSN CCCEEEECCCCCCCH | 37.64 | 24489116 | |
| 225 | Phosphorylation | TKDRGNMSNTEYRKY ECCCCCCCHHHHHHH | 44.60 | 27017623 | |
| 227 | Phosphorylation | DRGNMSNTEYRKYIT CCCCCCHHHHHHHHH | 27.38 | 27017623 | |
| 229 | Phosphorylation | GNMSNTEYRKYITNQ CCCCHHHHHHHHHHH | 15.46 | 27017623 | |
| 231 | Acetylation | MSNTEYRKYITNQRK CCHHHHHHHHHHHHH | 39.85 | 25381059 | |
| 262 | Phosphorylation | SLPPRAMSLQSFPNG CCCCCCCCCCCCCCC | 23.44 | 28152593 | |
| 265 | Phosphorylation | PRAMSLQSFPNGNPL CCCCCCCCCCCCCCC | 48.22 | 23749301 | |
| 289 | Phosphorylation | FQPNKMVSANYSRSN CCCCCEEEECCCCCC | 13.80 | 22369663 | |
| 292 | Phosphorylation | NKMVSANYSRSNSLM CCEEEECCCCCCCCC | 12.74 | 22369663 | |
| 293 | Phosphorylation | KMVSANYSRSNSLMS CEEEECCCCCCCCCC | 29.10 | 22369663 | |
| 295 | Phosphorylation | VSANYSRSNSLMSGP EEECCCCCCCCCCCC | 25.49 | 19684113 | |
| 297 | Phosphorylation | ANYSRSNSLMSGPPG ECCCCCCCCCCCCCC | 27.05 | 19684113 | |
| 300 | Phosphorylation | SRSNSLMSGPPGQFR CCCCCCCCCCCCCCC | 54.14 | 28889911 | |
| 346 | Phosphorylation | QPPQQPRTLSLTNGP CCCCCCCEEECCCCC | 27.64 | 28132839 | |
| 348 | Phosphorylation | PQQPRTLSLTNGPRY CCCCCEEECCCCCCC | 32.32 | 22369663 | |
| 350 | Phosphorylation | QPRTLSLTNGPRYSP CCCEEECCCCCCCCC | 34.45 | 22369663 | |
| 355 | Phosphorylation | SLTNGPRYSPQNPRP ECCCCCCCCCCCCCC | 28.03 | 22369663 | |
| 356 | Phosphorylation | LTNGPRYSPQNPRPF CCCCCCCCCCCCCCC | 22.68 | 22369663 | |
| 370 | Phosphorylation | FAGHQQISQRQQQQQ CCCHHHHHHHHHHHH | 18.25 | 22369663 | |
| 386 | Phosphorylation | QLQLHPMSEGYRTMS HHCCCCCCCCCCCCC | 32.11 | 23749301 | |
| 393 | Phosphorylation | SEGYRTMSLQSQNVP CCCCCCCCCCCCCCC | 23.73 | 28152593 | |
| 396 | Phosphorylation | YRTMSLQSQNVPQGF CCCCCCCCCCCCCCC | 29.08 | 23749301 | |
| 407 | Phosphorylation | PQGFNPWSPNDNDRK CCCCCCCCCCCCCCH | 18.32 | 23749301 | |
| 417 | Phosphorylation | DNDRKAVSMKQPISQ CCCCHHHHCCCCCCH | 25.73 | 21440633 | |
| 419 | Acetylation | DRKAVSMKQPISQSS CCHHHHCCCCCCHHH | 45.47 | 25381059 | |
| 423 | Phosphorylation | VSMKQPISQSSISSK HHCCCCCCHHHCCCC | 30.60 | 22369663 | |
| 425 | Phosphorylation | MKQPISQSSISSKNN CCCCCCHHHCCCCCC | 23.89 | 22369663 | |
| 426 | Phosphorylation | KQPISQSSISSKNNS CCCCCHHHCCCCCCC | 20.89 | 22369663 | |
| 428 | Phosphorylation | PISQSSISSKNNSAY CCCHHHCCCCCCCCC | 36.89 | 22369663 | |
| 429 | Phosphorylation | ISQSSISSKNNSAYS CCHHHCCCCCCCCCC | 37.42 | 22369663 | |
| 433 | Phosphorylation | SISSKNNSAYSIPNV HCCCCCCCCCCCCCC | 37.67 | 20377248 | |
| 435 | Phosphorylation | SSKNNSAYSIPNVQN CCCCCCCCCCCCCCC | 13.62 | 20377248 | |
| 436 | Phosphorylation | SKNNSAYSIPNVQNN CCCCCCCCCCCCCCC | 31.14 | 21551504 | |
| 444 | Phosphorylation | IPNVQNNSLTTFSPS CCCCCCCCCCEECCC | 34.34 | 20377248 | |
| 446 | Phosphorylation | NVQNNSLTTFSPSSP CCCCCCCCEECCCCC | 26.14 | 21551504 | |
| 449 | Phosphorylation | NNSLTTFSPSSPTDA CCCCCEECCCCCCCC | 23.06 | 27738172 | |
| 451 | Phosphorylation | SLTTFSPSSPTDATA CCCEECCCCCCCCCC | 47.99 | 28889911 | |
| 452 | Phosphorylation | LTTFSPSSPTDATAM CCEECCCCCCCCCCC | 34.89 | 20377248 | |
| 454 | Phosphorylation | TFSPSSPTDATAMPN EECCCCCCCCCCCCC | 39.97 | 21082442 | |
| 457 | Phosphorylation | PSSPTDATAMPNSTK CCCCCCCCCCCCCCC | 26.71 | 28889911 | |
| 467 | Phosphorylation | PNSTKQGSSPLKKQV CCCCCCCCCCCCCCC | 26.70 | 21440633 | |
| 468 | Phosphorylation | NSTKQGSSPLKKQVN CCCCCCCCCCCCCCC | 40.87 | 29734811 | |
| 492 | Phosphorylation | KLNVLQLSTPQQNEL CCCEEECCCCCHHHH | 25.69 | 28152593 | |
| 493 | Phosphorylation | LNVLQLSTPQQNELK CCEEECCCCCHHHHH | 33.44 | 28152593 | |
| 512 | Phosphorylation | KLAEMEKSLREREAL HHHHHHHHHHHHHHH | 21.25 | 24961812 | |
| 532 | Phosphorylation | KERAEKNTEANEEEE HHHHHHHCCCCHHHH | 47.76 | 28889911 | |
| 541 | Phosphorylation | ANEEEEISHESDDLN CCHHHHHCCCCCCCC | 25.20 | 20377248 | |
| 544 | Phosphorylation | EEEISHESDDLNLRP HHHHCCCCCCCCCCH | 30.88 | 25521595 | |
| 553 | Phosphorylation | DLNLRPASALETGLK CCCCCHHHHHHHCCH | 35.75 | 21440633 | |
| 557 | Phosphorylation | RPASALETGLKDLKL CHHHHHHHCCHHCCC | 48.98 | 24961812 | |
| 566 | Phosphorylation | LKDLKLESESAVANR CHHCCCCCHHHHHHH | 47.49 | 28889911 | |
| 568 | Phosphorylation | DLKLESESAVANRAS HCCCCCHHHHHHHHC | 37.00 | 28889911 | |
| 575 | Phosphorylation | SAVANRASLSTFSST HHHHHHHCHHHHHHC | 21.44 | 28889911 | |
| 577 | Phosphorylation | VANRASLSTFSSTFS HHHHHCHHHHHHCCC | 25.55 | 28132839 | |
| 578 | Phosphorylation | ANRASLSTFSSTFSD HHHHCHHHHHHCCCC | 32.60 | 22369663 | |
| 580 | Phosphorylation | RASLSTFSSTFSDSP HHCHHHHHHCCCCCC | 28.67 | 22369663 | |
| 581 | Phosphorylation | ASLSTFSSTFSDSPS HCHHHHHHCCCCCCC | 29.31 | 22369663 | |
| 582 | Phosphorylation | SLSTFSSTFSDSPSK CHHHHHHCCCCCCCC | 26.43 | 22369663 | |
| 584 | Phosphorylation | STFSSTFSDSPSKQR HHHHHCCCCCCCCCC | 36.95 | 22369663 | |
| 586 | Phosphorylation | FSSTFSDSPSKQRII HHHCCCCCCCCCCEE | 29.85 | 22369663 | |
| 588 | Phosphorylation | STFSDSPSKQRIINT HCCCCCCCCCCEEEC | 45.43 | 20377248 | |
| 605 | Phosphorylation | GMYKLENSTDINEYV CEEEECCCCCHHHCE | 20.34 | 20377248 | |
| 606 | Phosphorylation | MYKLENSTDINEYVT EEEECCCCCHHHCEE | 53.10 | 20377248 | |
| 611 | Phosphorylation | NSTDINEYVTAQEFP CCCCHHHCEEHHCCC | 9.90 | 20377248 | |
| 613 | Phosphorylation | TDINEYVTAQEFPSP CCHHHCEEHHCCCCC | 23.01 | 20377248 | |
| 619 | Phosphorylation | VTAQEFPSPGKYNSN EEHHCCCCCCCCCCC | 52.16 | 22369663 | |
| 649 | Phosphorylation | FNTSKRASLLQSIPE CCHHHHHHHHHCCCC | 33.38 | 19823750 | |
| 653 | Phosphorylation | KRASLLQSIPERDPK HHHHHHHCCCCCCCC | 39.83 | 21440633 | |
| 664 | Phosphorylation | RDPKRNVSDATIKRR CCCCCCCCHHHEEEE | 25.69 | 19823750 | |
| 667 | Phosphorylation | KRNVSDATIKRRESD CCCCCHHHEEEECCC | 31.83 | 24909858 | |
| 673 | Phosphorylation | ATIKRRESDGNGRRL HHEEEECCCCCCCCC | 49.35 | 27214570 | |
| 681 | Phosphorylation | DGNGRRLSNVNISMN CCCCCCCCCEEECCC | 36.60 | 22369663 | |
| 686 | Phosphorylation | RLSNVNISMNQENIN CCCCEEECCCCHHCC | 13.38 | 28132839 | |
| 709 | Phosphorylation | NNRDGHLSAVSHMSS CCCCCCCHHHEECCC | 22.43 | 28889911 | |
| 712 | Phosphorylation | DGHLSAVSHMSSSSR CCCCHHHEECCCHHC | 17.12 | 28889911 | |
| 715 | Phosphorylation | LSAVSHMSSSSRRSF CHHHEECCCHHCCCC | 22.96 | 28889911 | |
| 716 | Phosphorylation | SAVSHMSSSSRRSFI HHHEECCCHHCCCCH | 25.43 | 30377154 | |
| 717 | Phosphorylation | AVSHMSSSSRRSFIS HHEECCCHHCCCCHH | 22.13 | 28889911 | |
| 718 | Phosphorylation | VSHMSSSSRRSFISN HEECCCHHCCCCHHC | 33.39 | 28889911 | |
| 721 | Phosphorylation | MSSSSRRSFISNTLP CCCHHCCCCHHCCCC | 26.31 | 22369663 | |
| 724 | Phosphorylation | SSRRSFISNTLPLNI HHCCCCHHCCCCCCC | 23.04 | 22369663 | |
| 726 | Phosphorylation | RRSFISNTLPLNIDS CCCCHHCCCCCCCCC | 23.98 | 22369663 | |
| 733 | Phosphorylation | TLPLNIDSASESDNF CCCCCCCCCCCCCCC | 29.87 | 22369663 | |
| 735 | Phosphorylation | PLNIDSASESDNFVP CCCCCCCCCCCCCCC | 41.40 | 21440633 | |
| 737 | Phosphorylation | NIDSASESDNFVPHM CCCCCCCCCCCCCCC | 35.05 | 22369663 | |
| 747 | Phosphorylation | FVPHMDGSPSKTKSA CCCCCCCCCCCCCCC | 23.03 | 22369663 | |
| 749 | Phosphorylation | PHMDGSPSKTKSAPV CCCCCCCCCCCCCCC | 55.44 | 22369663 | |
| 751 | Phosphorylation | MDGSPSKTKSAPVSY CCCCCCCCCCCCCCC | 34.27 | 21440633 | |
| 753 | Phosphorylation | GSPSKTKSAPVSYDK CCCCCCCCCCCCCCC | 42.93 | 28889911 | |
| 757 | Phosphorylation | KTKSAPVSYDKDGMN CCCCCCCCCCCCCCC | 26.93 | 26447709 | |
| 758 | Phosphorylation | TKSAPVSYDKDGMNA CCCCCCCCCCCCCCC | 27.52 | 19779198 | |
| 766 | Phosphorylation | DKDGMNASEEDFSFD CCCCCCCCHHHCCCC | 36.19 | 22369663 | |
| 771 | Phosphorylation | NASEEDFSFDNTLAK CCCHHHCCCCCCCCC | 43.97 | 22369663 | |
| 775 | Phosphorylation | EDFSFDNTLAKPYEP HHCCCCCCCCCCCCC | 29.91 | 22369663 | |
| 780 | Phosphorylation | DNTLAKPYEPLYARR CCCCCCCCCCCEECC | 29.49 | 21551504 | |
| 784 | Phosphorylation | AKPYEPLYARRGDIT CCCCCCCEECCCCCC | 14.58 | 21440633 | |
| 791 | Phosphorylation | YARRGDITSAGSTSG EECCCCCCCCCCCCC | 19.77 | 20377248 | |
| 792 | Phosphorylation | ARRGDITSAGSTSGE ECCCCCCCCCCCCCC | 30.85 | 20377248 | |
| 795 | Phosphorylation | GDITSAGSTSGEDSS CCCCCCCCCCCCCCC | 21.08 | 22369663 | |
| 796 | Phosphorylation | DITSAGSTSGEDSSQ CCCCCCCCCCCCCCC | 39.57 | 22369663 | |
| 797 | Phosphorylation | ITSAGSTSGEDSSQP CCCCCCCCCCCCCCC | 41.71 | 22369663 | |
| 801 | Phosphorylation | GSTSGEDSSQPKMIT CCCCCCCCCCCEEEE | 26.94 | 22369663 | |
| 802 | Phosphorylation | STSGEDSSQPKMITI CCCCCCCCCCEEEEE | 63.92 | 22369663 | |
| 851 | Phosphorylation | LEERIRLYETNNSAP HHHHHHHHHCCCCCC | 15.74 | 22369663 | |
| 853 | Phosphorylation | ERIRLYETNNSAPSF HHHHHHHCCCCCCCC | 26.58 | 22369663 | |
| 856 | Phosphorylation | RLYETNNSAPSFDDS HHHHCCCCCCCCCCC | 43.56 | 22369663 | |
| 859 | Phosphorylation | ETNNSAPSFDDSSSV HCCCCCCCCCCCCCC | 40.81 | 22369663 | |
| 863 | Phosphorylation | SAPSFDDSSSVSFSD CCCCCCCCCCCCHHH | 26.76 | 22369663 | |
| 864 | Phosphorylation | APSFDDSSSVSFSDF CCCCCCCCCCCHHHH | 41.58 | 22369663 | |
| 865 | Phosphorylation | PSFDDSSSVSFSDFE CCCCCCCCCCHHHHH | 26.23 | 22369663 | |
| 867 | Phosphorylation | FDDSSSVSFSDFEKE CCCCCCCCHHHHHHH | 22.45 | 22369663 | |
| 869 | Phosphorylation | DSSSVSFSDFEKELR CCCCCCHHHHHHHHH | 33.61 | 22369663 | |
| 933 | Phosphorylation | KLIDERDSEIEMLKG HHHHHHHHHHHHHHH | 46.85 | 25752575 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of YM11_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of YM11_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of YM11_YEAST !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
loading...
| Phosphorylation | |
| Reference | PubMed |
| "A multidimensional chromatography technology for in-depthphosphoproteome analysis."; Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.; Mol. Cell. Proteomics 7:1389-1396(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-553; SER-681; SER-766AND SER-867, AND MASS SPECTROMETRY. | |
| "Analysis of phosphorylation sites on proteins from Saccharomycescerevisiae by electron transfer dissociation (ETD) massspectrometry."; Chi A., Huttenhower C., Geer L.Y., Coon J.J., Syka J.E.P., Bai D.L.,Shabanowitz J., Burke D.J., Troyanskaya O.G., Hunt D.F.; Proc. Natl. Acad. Sci. U.S.A. 104:2193-2198(2007). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-649, AND MASSSPECTROMETRY. | |
