UniProt ID | PTR3_YEAST | |
---|---|---|
UniProt AC | P43606 | |
Protein Name | SPS-sensor component PTR3 | |
Gene Name | PTR3 | |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
Sequence Length | 678 | |
Subcellular Localization |
Cell membrane Peripheral membrane protein Cytoplasmic side . |
|
Protein Description | Component of the SPS-sensor system, which regulates the expression of several amino acid-metabolizing enzymes and amino acid- and peptide-permeases in response to extracellular amino acid levels by controlling the activity of two transcription factors, STP1 and STP2.. | |
Protein Sequence | MHSHRQKWGRQTDIARVLDDIEHDLYLPQRLSLDGATGTDESHVQYGIVKDCSVLTCGCCISESLFNDLCRETSNKQTACPICQRENVRLLSAIKPLRDLARQIDFFRSTTGQGESESDELPAIVKTSPSSSSLSLTPSRSSSTAGLEADNKTLSDPTVKEKSSLLELFHIVASKMHNANTEVGSDHPLTTGTTRDQEEHTTKENYSSSLLEPNYDDHANWKILDNASNTRTVPIDNNFSLMSTDVTIPSTANYQTNSAHDLDEEKEYFFANCFPMYRKKFQFNTHPKFLGTKSKLFINQSISPDCTKFALITEHKWEIYSINPKDNSPQLVSCGKSSGEYGPNFNQLTEQSSSSLSTTSQASKKKKKNWSQRFCKLSNDFLIISGSQNILNVHDIHQNGKLIYTYVSRFPIRCIDIDPRSQIIAYGITGKDRHTGAEQALVVIQQITRNKVTLEPEFPPPITITLPYRDPINTIQLSHDAKYLTCSTALESRFLIISLQKINEPRLIMKSVRSIDTSLESEGITDTKLFPGNPNLMCITSTAFNSSPLVINTKITQINGVRTVAQPSMLIRVDEIGCKIHKCEISPRNDAIAFLDRNGSVYIMCAPTMMDNNEKRRTILVETVANAYRAYESATLRFNPEGNKLYILDRKGTFFVEDFAYGLPQSREITKCKQIFHK | |
Overview of Protein Modification Sites with Functional and Structural Information | ||
* ASA = Accessible Surface Area
Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
---|---|---|---|---|---|
116 | Phosphorylation | STTGQGESESDELPA CCCCCCCCCCCCCCE | 49.58 | 28889911 | |
118 | Phosphorylation | TGQGESESDELPAIV CCCCCCCCCCCCEEE | 45.74 | 27214570 | |
143 | Phosphorylation | LTPSRSSSTAGLEAD ECCCCCCCCCCCCCC | 24.43 | 28889911 | |
155 | Phosphorylation | EADNKTLSDPTVKEK CCCCCCCCCCCHHHH | 46.94 | 27017623 | |
158 | Phosphorylation | NKTLSDPTVKEKSSL CCCCCCCCHHHHHHH | 49.56 | 27017623 | |
160 | Ubiquitination | TLSDPTVKEKSSLLE CCCCCCHHHHHHHHH | 63.00 | 23749301 | |
164 | Phosphorylation | PTVKEKSSLLELFHI CCHHHHHHHHHHHHH | 48.30 | 21440633 | |
185 | Phosphorylation | NANTEVGSDHPLTTG CCCCCCCCCCCCCCC | 37.61 | 21440633 | |
206 | Phosphorylation | EHTTKENYSSSLLEP CCCCCCCCCCCCCCC | 15.83 | 24961812 | |
207 | Phosphorylation | HTTKENYSSSLLEPN CCCCCCCCCCCCCCC | 25.65 | 24961812 | |
208 | Phosphorylation | TTKENYSSSLLEPNY CCCCCCCCCCCCCCC | 18.04 | 24961812 | |
209 | Phosphorylation | TKENYSSSLLEPNYD CCCCCCCCCCCCCCC | 30.91 | 24961812 | |
228 | Phosphorylation | WKILDNASNTRTVPI CEEECCCCCCCEEEC | 45.01 | 22369663 | |
230 | Phosphorylation | ILDNASNTRTVPIDN EECCCCCCCEEECCC | 25.81 | 22369663 | |
525 | Phosphorylation | SLESEGITDTKLFPG CCCCCCCCCCCCCCC | 48.77 | 28889911 |
Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of PTR3_YEAST !! |
Modified Location | Modified Residue | Modification | Function | Reference | ||
---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of PTR3_YEAST !! |
* Distance = the distance between SAP position and PTM sites.
Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of PTR3_YEAST !! |
Kegg Drug | ||||||
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DrugBank | ||||||
There are no disease associations of PTM sites. |
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