PTR3_YEAST - dbPTM
PTR3_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID PTR3_YEAST
UniProt AC P43606
Protein Name SPS-sensor component PTR3
Gene Name PTR3
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 678
Subcellular Localization Cell membrane
Peripheral membrane protein
Cytoplasmic side .
Protein Description Component of the SPS-sensor system, which regulates the expression of several amino acid-metabolizing enzymes and amino acid- and peptide-permeases in response to extracellular amino acid levels by controlling the activity of two transcription factors, STP1 and STP2..
Protein Sequence MHSHRQKWGRQTDIARVLDDIEHDLYLPQRLSLDGATGTDESHVQYGIVKDCSVLTCGCCISESLFNDLCRETSNKQTACPICQRENVRLLSAIKPLRDLARQIDFFRSTTGQGESESDELPAIVKTSPSSSSLSLTPSRSSSTAGLEADNKTLSDPTVKEKSSLLELFHIVASKMHNANTEVGSDHPLTTGTTRDQEEHTTKENYSSSLLEPNYDDHANWKILDNASNTRTVPIDNNFSLMSTDVTIPSTANYQTNSAHDLDEEKEYFFANCFPMYRKKFQFNTHPKFLGTKSKLFINQSISPDCTKFALITEHKWEIYSINPKDNSPQLVSCGKSSGEYGPNFNQLTEQSSSSLSTTSQASKKKKKNWSQRFCKLSNDFLIISGSQNILNVHDIHQNGKLIYTYVSRFPIRCIDIDPRSQIIAYGITGKDRHTGAEQALVVIQQITRNKVTLEPEFPPPITITLPYRDPINTIQLSHDAKYLTCSTALESRFLIISLQKINEPRLIMKSVRSIDTSLESEGITDTKLFPGNPNLMCITSTAFNSSPLVINTKITQINGVRTVAQPSMLIRVDEIGCKIHKCEISPRNDAIAFLDRNGSVYIMCAPTMMDNNEKRRTILVETVANAYRAYESATLRFNPEGNKLYILDRKGTFFVEDFAYGLPQSREITKCKQIFHK
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
116PhosphorylationSTTGQGESESDELPA
CCCCCCCCCCCCCCE
49.5828889911
118PhosphorylationTGQGESESDELPAIV
CCCCCCCCCCCCEEE
45.7427214570
143PhosphorylationLTPSRSSSTAGLEAD
ECCCCCCCCCCCCCC
24.4328889911
155PhosphorylationEADNKTLSDPTVKEK
CCCCCCCCCCCHHHH
46.9427017623
158PhosphorylationNKTLSDPTVKEKSSL
CCCCCCCCHHHHHHH
49.5627017623
160UbiquitinationTLSDPTVKEKSSLLE
CCCCCCHHHHHHHHH
63.0023749301
164PhosphorylationPTVKEKSSLLELFHI
CCHHHHHHHHHHHHH
48.3021440633
185PhosphorylationNANTEVGSDHPLTTG
CCCCCCCCCCCCCCC
37.6121440633
206PhosphorylationEHTTKENYSSSLLEP
CCCCCCCCCCCCCCC
15.8324961812
207PhosphorylationHTTKENYSSSLLEPN
CCCCCCCCCCCCCCC
25.6524961812
208PhosphorylationTTKENYSSSLLEPNY
CCCCCCCCCCCCCCC
18.0424961812
209PhosphorylationTKENYSSSLLEPNYD
CCCCCCCCCCCCCCC
30.9124961812
228PhosphorylationWKILDNASNTRTVPI
CEEECCCCCCCEEEC
45.0122369663
230PhosphorylationILDNASNTRTVPIDN
EECCCCCCCEEECCC
25.8122369663
525PhosphorylationSLESEGITDTKLFPG
CCCCCCCCCCCCCCC
48.7728889911

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of PTR3_YEAST !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of PTR3_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of PTR3_YEAST !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
PTR3_YEASTPTR3physical
11489133
SSY5_YEASTSSY5genetic
11489133
LEU3_YEASTLEU2genetic
10409731
ASI1_YEASTASI1genetic
11454748
ASI2_YEASTASI2genetic
11454748
ASI3_YEASTASI3genetic
11454748
BRO1_YEASTBRO1genetic
11454748
BUL1_YEASTBUL1genetic
11454748
UBP4_YEASTDOA4genetic
11454748
RSP5_YEASTRSP5genetic
11454748
CYC8_YEASTCYC8genetic
11454748
TUP1_YEASTTUP1genetic
11454748
UBA1_YEASTUBA1genetic
11454748
VPS20_YEASTVPS20genetic
11454748
VPS36_YEASTVPS36genetic
11454748
SSY5_YEASTSSY5genetic
15509782
SSY5_YEASTSSY5physical
17984223
PTR3_YEASTPTR3physical
17984223
STP2_YEASTSTP2genetic
19906648
MDM10_YEASTMDM10genetic
20093466
ETR1_YEASTETR1genetic
20093466
CCZ1_YEASTCCZ1genetic
20093466
RV161_YEASTRVS161genetic
20093466
BUD31_YEASTBUD31genetic
20093466
ATG9_YEASTATG9genetic
20093466
VAM6_YEASTVAM6genetic
20093466
PP2C1_YEASTPTC1genetic
20093466
PAA1_YEASTPAA1genetic
20093466
TPS2_YEASTTPS2genetic
20093466
VPS41_YEASTVPS41genetic
20093466
RMD5_YEASTRMD5genetic
20093466
SSD1_YEASTSSD1genetic
20093466
YD306_YEASTYDR306Cgenetic
20093466
SSF2_YEASTSSF2genetic
20093466
VAM7_YEASTVAM7genetic
20093466
CWH41_YEASTCWH41genetic
20093466
PEF1_YEASTPEF1genetic
20093466
YG35_YEASTYGR125Wgenetic
20093466
SMI1_YEASTSMI1genetic
20093466
SLT2_YEASTSLT2genetic
20093466
HTD2_YEASTHTD2genetic
20093466
PEX18_YEASTPEX18genetic
20093466
ATG7_YEASTATG7genetic
20093466
PEX2_YEASTPEX2genetic
20093466
RPA34_YEASTRPA34genetic
20093466
BCK1_YEASTBCK1genetic
20093466
LPLA_YEASTAIM22genetic
20093466
SNX4_YEASTSNX4genetic
20093466
VPS55_YEASTVPS55genetic
20093466
DHOM_YEASTHOM6genetic
20093466
LST4_YEASTLST4genetic
20093466
ATG10_YEASTATG10genetic
20093466
UBI4P_YEASTUBI4genetic
20093466
XDJ1_YEASTXDJ1genetic
20093466
GBLP_YEASTASC1genetic
20093466
VPS27_YEASTVPS27genetic
20093466
ATG3_YEASTATG3genetic
20093466
TRM11_YEASTTRM11genetic
20093466
PHO80_YEASTPHO80genetic
20093466
BUD21_YEASTBUD21genetic
20093466
LIPA_YEASTLIP5genetic
20093466
NCBP2_YEASTCBC2genetic
20093466
ATG5_YEASTATG5genetic
20093466
SYH1_YEASTSYH1genetic
20093466
GAP1_YEASTGAP1genetic
22844449
KAD2_YEASTADK1physical
22940862
SSY5_YEASTSSY5physical
23447701
PTR3_YEASTPTR3physical
23447701
BCK1_YEASTBCK1genetic
22282571
SLT2_YEASTSLT2genetic
22282571

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of PTR3_YEAST

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Related Literatures of Post-Translational Modification

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