LYPD4_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: LYPD4_HUMAN
• UniProt AC: Q6UWN0
• Protein Name: Ly6/PLAUR domain-containing protein 4
• Gene Name: LYPD4
• Organism: Homo sapiens (Human).
• Sequence Length: 246
• Subcellular Localization: Cell membrane ; Lipid-anchor, GPI-anchor .
• Protein Sequence: MGPQHLRLVQLFCLLGAISTLPRAGALLCYEATASRFRAVAFHNWKWLLMRNMVCKLQEGCEETLVFIETGTARGVVGFKGCSSSSSYPAQISYLVSPPGVSIASYSRVCRSYLCNNLTNLEPFVKLKASTPKSITSASCSCPTCVGEHMKDCLPNFVTTNSCPLAASTCYSSTLKFQAGFLNTTFLLMGCAREHNQLLADFHHIGSIKVTEVLNILEKSQIVGAASSRQDPAWGVVLGLLFAFRD

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
35	Phosphorylation	LCYEATASRFRAVAF HHHHHCHHHHHHHHH	27.83	-
83	Phosphorylation	VVGFKGCSSSSSYPA EECCCCCCCCCCCCE	41.76	22210691
84	Phosphorylation	VGFKGCSSSSSYPAQ ECCCCCCCCCCCCEE	38.01	22210691
102	Phosphorylation	LVSPPGVSIASYSRV EECCCCCCHHHHHHH	20.53	22210691
117	N-linked_Glycosylation	CRSYLCNNLTNLEPF HHHHHCCCCCCCCCE	47.44	UniProtKB CARBOHYD
225	GPI-anchor	EKSQIVGAASSRQDP HHHCCCCCCCCCCCH	8.02	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of LYPD4_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of LYPD4_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of LYPD4_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
NPTX2_HUMAN	NPTX2	physical	28514442
OBSCN_HUMAN	OBSCN	physical	28514442
FXL18_HUMAN	FBXL18	physical	28514442
F198A_HUMAN	FAM198A	physical	28514442
NPTX1_HUMAN	NPTX1	physical	28514442
ERN1_HUMAN	ERN1	physical	28514442
GDF11_HUMAN	GDF11	physical	28514442
FUT11_HUMAN	FUT11	physical	28514442
PRR14_HUMAN	PRR14	physical	28514442
NBR1_HUMAN	NBR1	physical	28514442
ERG7_HUMAN	LSS	physical	28514442
TRM44_HUMAN	TRMT44	physical	28514442
FANCJ_HUMAN	BRIP1	physical	28514442
GRB1L_HUMAN	GREB1L	physical	28514442
ATS2_HUMAN	ADAMTS2	physical	28514442
TBA4A_HUMAN	TUBA4A	physical	28514442
JMJD4_HUMAN	JMJD4	physical	28514442
NPRL3_HUMAN	NPRL3	physical	28514442
TSN6_HUMAN	TSPAN6	physical	28514442
AP3M2_HUMAN	AP3M2	physical	28514442
TROAP_HUMAN	TROAP	physical	28514442
KI18A_HUMAN	KIF18A	physical	28514442
UBP34_HUMAN	USP34	physical	28514442
TYDP2_HUMAN	TDP2	physical	28514442
GALNS_HUMAN	GALNS	physical	28514442
GLT12_HUMAN	GALNT12	physical	28514442
APAF_HUMAN	APAF1	physical	28514442
MICA_HUMAN	MICA	physical	28514442
MYCPP_HUMAN	DENND4A	physical	28514442
STIL_HUMAN	STIL	physical	28514442
VPS16_HUMAN	VPS16	physical	28514442
KIF1A_HUMAN	KIF1A	physical	28514442
PCSK5_HUMAN	PCSK5	physical	28514442
VP13B_HUMAN	VPS13B	physical	28514442
PPT2_HUMAN	PPT2	physical	28514442
BORA_HUMAN	BORA	physical	28514442
TOR3A_HUMAN	TOR3A	physical	28514442
GNPAT_HUMAN	GNPAT	physical	28514442
ELP6_HUMAN	ELP6	physical	28514442
WAP53_HUMAN	WRAP53	physical	28514442
MAOX_HUMAN	ME1	physical	28514442
FBN2_HUMAN	FBN2	physical	28514442
VPS18_HUMAN	VPS18	physical	28514442
S23IP_HUMAN	SEC23IP	physical	28514442
ADCK1_HUMAN	ADCK1	physical	28514442
AP5Z1_HUMAN	AP5Z1	physical	28514442
LMLN_HUMAN	LMLN	physical	28514442
DPYL4_HUMAN	DPYSL4	physical	28514442
ANAG_HUMAN	NAGLU	physical	28514442
LETM1_HUMAN	LETM1	physical	28514442
CTR9_HUMAN	CTR9	physical	28514442
LRFN3_HUMAN	LRFN3	physical	28514442
XYLT2_HUMAN	XYLT2	physical	28514442
EDEM2_HUMAN	EDEM2	physical	28514442
ASPH2_HUMAN	ASPHD2	physical	28514442
PANK4_HUMAN	PANK4	physical	28514442
SMG8_HUMAN	SMG8	physical	28514442
N42L2_HUMAN	N4BP2L2	physical	28514442
ANM6_HUMAN	PRMT6	physical	28514442
PGLT1_HUMAN	POGLUT1	physical	28514442
OAF_HUMAN	OAF	physical	28514442
ECD_HUMAN	ECD	physical	28514442
FA69A_HUMAN	FAM69A	physical	28514442
LRWD1_HUMAN	LRWD1	physical	28514442
DPOE1_HUMAN	POLE	physical	28514442
ESPL1_HUMAN	ESPL1	physical	28514442

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.