dbPTM

MYCPP_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	MYCPP_HUMAN
UniProt AC	Q7Z401
Protein Name	C-myc promoter-binding protein
Gene Name	DENND4A
Organism	Homo sapiens (Human).
Sequence Length	1863
Subcellular Localization	Nucleus .
Protein Description	Probable guanine nucleotide exchange factor (GEF) which may activate RAB10. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. According to PubMed:8056341, it may bind to ISRE-like element (interferon-stimulated response element) of MYC P2 promoter..
Protein Sequence	MIEDKGPRVADYFVVAGLTDVSKPLEEEIHFNDACHKVAKPKEPITDVSVIIKSLGEEVPQDYICIDVTPTGLSADLNNGSLVGPQIYLCYRRGRDKPPLTDLGVLYDWKERLKQGCEIIQSTPYGRPANISGSTSSQRIYITYRRASENMTQNTLAVTDICIIIPSKGESPPHTFCKVDKNLNNSMWGSAVYLCYKKSVAKTNTVSYKAGLICRYPQEDYESFSLPESVPLFCLPMGATIECWPSNSKYPLPVFSTFVLTGASAEKVYGAAIQFYEPYSEENLTEKQRLLLGLTSADGKSDSSKTIHTNKCICLLSHWPFFDAFRKFLTFLYRYSISGPHVLPIEKHISHFMHKVPFPSPQRPRILVQLSPHDNLILSQPVSSPLPLSGGKFSTLLQNLGPENAVTLLVFAVTEHKILIHSLRPSVLTSVTEALVSMIFPFHWPCPYVPLCPLALADVLSAPCPFIVGIDSRYFDLYDPPPDVSCVDVDTNTISQIGDKKNVAWKILPKKPCKNLMNTLNNLHQQLAKLQQRPRDDGLMDLAINDYDFNSGKRLHMIDLEIQEAFLFFMASILKGYRSYLRPITQAPSETATDAASLFALQAFLRSRDRSHQKFYNMMTKTQMFIRFIEECSFVSDKDASLAFFDDCVDKVDMDKSGEVRLIELDESFKSEHTVFVTPPEIPHLPNGEEPPLQYSYNGFPVLRNNLFERPEGFLQAKKNKLPSKSSSPNSPLPMFRRTKQEIKSAHKIAKRYSSIPQMWSRCLLRHCYGLWFICLPAYVKVCHSKVRALKTAYDVLKKMQSKKMDPPDEVCYRILMQLCGQYDQPVLAVRVLFEMQKAGIDPNAITYGYYNKAVLESTWPSRSRSGYFLWTKVRNVVLGVTQFKRALKKHAHLSQTTLSGGQSDLGYNSLSKDEVRRGDTSTEDIQEEKDKKGSDCSSLSESESTKGSADCLPKLSYQNSSSIVRLTGTSNNSAGKISGESMESTPELLLISSLEDTNETRNIQSRCFRKRHKSDNETNLQQQVVWGNRNRNLSGGVLMGFMLNRINQEATPGDIVEKLGADAKILSNVISKSTRPNTLDIGKPPLRSKRDSLEKESSDDDTPFDGSNYLADKVDSPVIFDLEDLDSETDVSKAGCVATQNPKRIQRMNSSFSVKPFEKTDVATGFDPLSLLVAETEQQQKEEEEEDEDDSKSISTPSARRDLAEEIVMYMNNMSSPLTSRTPSIDLQRACDDKLNKKSPPLVKACRRSSLPPNSPKPVRLTKSKSYTKSEEKPRDRLWSSPAFSPTCPFREESQDTLTHSSPSFNLDTLLVPKLDVLRNSMFTAGKGVAEKASKWYSRFTMYTTSSKDQSSDRTSLSSVGAQDSESTSLTDEDVCHELEGPISSQETSATSGTKRIDLSRISLESSASLEGSLSKFALPGKSEVTSSFNASNTNIFQNYAMEVLISSCSRCRTCDCLVHDEEIMAGWTADDSNLNTTCPFCGNIFLPFLNIEIRDLRRPGRYFLKSSPSTENMHFPSSISSQTRQSCISTSASGLDTSALSVQGNFDLNSKSKLQENFCTRSIQIPANRSKTAMSKCPIFPMARSISTSGPLDKEDTGRQKLISTGSLPATLQGATDSLGLEWHLPSPDPVTVPYLSPLVVWKELESLLENEGDHAITVADFVDHHPIVFWNLVWYFRRLDLPSNLPGLILSSEHCNKYSKIPRHCMSEDSKYVLIQMLWDNMKLHQDPGQPLYILWNAHTQKYPMVHLLQKSDNSFNQELLKSMVKSIKMNDVYGPMSQILETLNKCPHFKRQRSLYREILFLSLVALGRENIDIDAFDKEYKMAYDRLTPSQVKSTHNCDRPPSTGVMECRKTFGEPYL

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
12	Phosphorylation	KGPRVADYFVVAGLT CCHHHHCEEEEEECC	6.63	28258704
22	Phosphorylation	VAGLTDVSKPLEEEI EEECCCCCCCHHHCC	31.22	24719451
167	Phosphorylation	DICIIIPSKGESPPH EEEEEECCCCCCCCC	42.77	24719451
178	Ubiquitination	SPPHTFCKVDKNLNN CCCCCCEECCCCCCC	49.64	-
186	Phosphorylation	VDKNLNNSMWGSAVY CCCCCCCCCCHHHHH	18.16	-
190	Phosphorylation	LNNSMWGSAVYLCYK CCCCCCHHHHHHHHH	10.07	-
199	Phosphorylation	VYLCYKKSVAKTNTV HHHHHHHCCCCCCCC	24.13	-
202	Ubiquitination	CYKKSVAKTNTVSYK HHHHCCCCCCCCEEE	39.90	-
207	Phosphorylation	VAKTNTVSYKAGLIC CCCCCCCEEEEEEEE	20.91	-
208	Phosphorylation	AKTNTVSYKAGLICR CCCCCCEEEEEEEEC	10.67	-
287	Ubiquitination	SEENLTEKQRLLLGL CCCCCCHHHHHHHCC	35.17	-
295	Phosphorylation	QRLLLGLTSADGKSD HHHHHCCCCCCCCCC	21.77	-
296	Phosphorylation	RLLLGLTSADGKSDS HHHHCCCCCCCCCCC	29.43	-
422	Phosphorylation	EHKILIHSLRPSVLT CCHHHHHHCCHHHHH	21.05	24719451
519	Phosphorylation	PCKNLMNTLNNLHQQ HHHHHHHHHHHHHHH	19.52	20068231
547	Phosphorylation	MDLAINDYDFNSGKR CCEEECEECCCCCCE	20.25	-
572	Phosphorylation	AFLFFMASILKGYRS HHHHHHHHHHHHHHH	19.37	24719451
641	Phosphorylation	FVSDKDASLAFFDDC CCCCCCCCHHEEHHH	30.29	28555341
718	Ubiquitination	PEGFLQAKKNKLPSK CHHHHHHHHCCCCCC	43.87	-
724	Phosphorylation	AKKNKLPSKSSSPNS HHHCCCCCCCCCCCC	56.45	24719451
726	Phosphorylation	KNKLPSKSSSPNSPL HCCCCCCCCCCCCCC	40.15	30266825
727	Phosphorylation	NKLPSKSSSPNSPLP CCCCCCCCCCCCCCH	54.26	30266825
728	Phosphorylation	KLPSKSSSPNSPLPM CCCCCCCCCCCCCHH	34.88	23401153
731	Phosphorylation	SKSSSPNSPLPMFRR CCCCCCCCCCHHHHH	31.06	23401153
753	Phosphorylation	AHKIAKRYSSIPQMW HHHHHHHHCCCHHHH	13.18	30108239
754	Phosphorylation	HKIAKRYSSIPQMWS HHHHHHHCCCHHHHH	26.31	30108239
755	Phosphorylation	KIAKRYSSIPQMWSR HHHHHHCCCHHHHHH	29.38	30108239
823	Phosphorylation	LMQLCGQYDQPVLAV HHHHHCCCCCCHHHH	11.22	-
882	Phosphorylation	RNVVLGVTQFKRALK HHHHHHHHHHHHHHH	26.87	24670416
895	Phosphorylation	LKKHAHLSQTTLSGG HHHCCCCCCCCCCCC	18.66	28857561
897	Phosphorylation	KHAHLSQTTLSGGQS HCCCCCCCCCCCCCC	26.74	28857561
898	Phosphorylation	HAHLSQTTLSGGQSD CCCCCCCCCCCCCCC	15.99	28857561
900	Phosphorylation	HLSQTTLSGGQSDLG CCCCCCCCCCCCCCC	38.49	22496350
904	Phosphorylation	TTLSGGQSDLGYNSL CCCCCCCCCCCCCCC	37.77	27080861
908	Phosphorylation	GGQSDLGYNSLSKDE CCCCCCCCCCCCHHH	14.63	28060719
910	Phosphorylation	QSDLGYNSLSKDEVR CCCCCCCCCCHHHHH	26.07	30576142
912	Phosphorylation	DLGYNSLSKDEVRRG CCCCCCCCHHHHHCC	37.57	28060719
921	Phosphorylation	DEVRRGDTSTEDIQE HHHHCCCCCHHHHHH	40.13	23401153
922	Phosphorylation	EVRRGDTSTEDIQEE HHHCCCCCHHHHHHH	34.24	23927012
923	Phosphorylation	VRRGDTSTEDIQEEK HHCCCCCHHHHHHHH	39.51	30576142
935	Phosphorylation	EEKDKKGSDCSSLSE HHHHCCCCCCCCCCC	44.30	25159151
938	Phosphorylation	DKKGSDCSSLSESES HCCCCCCCCCCCCCC	39.03	25159151
939	Phosphorylation	KKGSDCSSLSESEST CCCCCCCCCCCCCCC	42.10	21815630
941	Phosphorylation	GSDCSSLSESESTKG CCCCCCCCCCCCCCC	40.81	21815630
941 (in isoform 2)	Phosphorylation	-	40.81	25159151
942 (in isoform 2)	Phosphorylation	-	64.91	25159151
943	Phosphorylation	DCSSLSESESTKGSA CCCCCCCCCCCCCCC	33.21	28450419
943 (in isoform 2)	Phosphorylation	-	33.21	25159151
945	Phosphorylation	SSLSESESTKGSADC CCCCCCCCCCCCCCC	44.70	28450419
946	Phosphorylation	SLSESESTKGSADCL CCCCCCCCCCCCCCC	35.06	30108239
947 (in isoform 2)	Phosphorylation	-	61.21	25159151
949	Phosphorylation	ESESTKGSADCLPKL CCCCCCCCCCCCCCC	23.61	21815630
957	Phosphorylation	ADCLPKLSYQNSSSI CCCCCCCCCCCCCCE	30.69	20068231
958	Phosphorylation	DCLPKLSYQNSSSIV CCCCCCCCCCCCCEE	23.34	20068231
961	Phosphorylation	PKLSYQNSSSIVRLT CCCCCCCCCCEEEEE	15.22	28450419
962	Phosphorylation	KLSYQNSSSIVRLTG CCCCCCCCCEEEEEE	31.47	28450419
963	Phosphorylation	LSYQNSSSIVRLTGT CCCCCCCCEEEEEEC	25.56	28450419
968	Phosphorylation	SSSIVRLTGTSNNSA CCCEEEEEECCCCCC	28.05	20068231
970	Phosphorylation	SIVRLTGTSNNSAGK CEEEEEECCCCCCCC	24.05	20068231
971	Phosphorylation	IVRLTGTSNNSAGKI EEEEEECCCCCCCCC	35.05	20068231
974	Phosphorylation	LTGTSNNSAGKISGE EEECCCCCCCCCCCC	42.52	20068231
977	Ubiquitination	TSNNSAGKISGESME CCCCCCCCCCCCCCC	33.15	-
979	Phosphorylation	NNSAGKISGESMEST CCCCCCCCCCCCCCC	39.74	28348404
982	Phosphorylation	AGKISGESMESTPEL CCCCCCCCCCCCCCE	31.23	28348404
993	Phosphorylation	TPELLLISSLEDTNE CCCEEEEECCCCCCH	28.92	28348404
994	Phosphorylation	PELLLISSLEDTNET CCEEEEECCCCCCHH	28.87	28348404
1015	Phosphorylation	CFRKRHKSDNETNLQ HHHHHCCCCCCCCHH	39.27	25159151
1019	Phosphorylation	RHKSDNETNLQQQVV HCCCCCCCCHHHHHH	47.70	23401153
1035	Phosphorylation	GNRNRNLSGGVLMGF CCCCCCCCHHHHHHH	36.73	21712546
1052	Phosphorylation	NRINQEATPGDIVEK HHHCCCCCCHHHHHH	27.35	21815630
1068	Phosphorylation	GADAKILSNVISKST CCCHHHHHHHHCCCC	32.31	28555341
1072	Phosphorylation	KILSNVISKSTRPNT HHHHHHHCCCCCCCC	19.10	21130716
1075	Phosphorylation	SNVISKSTRPNTLDI HHHHCCCCCCCCCCC	54.61	28555341
1079	Phosphorylation	SKSTRPNTLDIGKPP CCCCCCCCCCCCCCC	28.61	28555341
1089	Phosphorylation	IGKPPLRSKRDSLEK CCCCCCCCCCHHCCC	39.46	24144214
1093	Phosphorylation	PLRSKRDSLEKESSD CCCCCCHHCCCCCCC	42.32	28102081
1098	Phosphorylation	RDSLEKESSDDDTPF CHHCCCCCCCCCCCC	50.57	22167270
1099	Phosphorylation	DSLEKESSDDDTPFD HHCCCCCCCCCCCCC	46.26	22167270
1103	Phosphorylation	KESSDDDTPFDGSNY CCCCCCCCCCCCHHH	32.61	22167270
1108	Phosphorylation	DDTPFDGSNYLADKV CCCCCCCHHHHHCCC	24.93	22167270
1110	Phosphorylation	TPFDGSNYLADKVDS CCCCCHHHHHCCCCC	12.64	22167270
1117	Phosphorylation	YLADKVDSPVIFDLE HHHCCCCCCEEEEHH	24.85	19413330
1128	Phosphorylation	FDLEDLDSETDVSKA EEHHHCCCCCCHHHC	50.09	22115753
1130	Phosphorylation	LEDLDSETDVSKAGC HHHCCCCCCHHHCCC	45.73	22617229
1133	Phosphorylation	LDSETDVSKAGCVAT CCCCCCHHHCCCEEC	21.43	20873877
1151	Phosphorylation	KRIQRMNSSFSVKPF HHHHHCCCCCCCCCC	24.34	23401153
1152	Phosphorylation	RIQRMNSSFSVKPFE HHHHCCCCCCCCCCC	19.28	25159151
1154	Phosphorylation	QRMNSSFSVKPFEKT HHCCCCCCCCCCCCC	31.05	21712546
1192	Phosphorylation	EEEDEDDSKSISTPS HHCCCCCCCCCCCHH	40.39	-
1194	Phosphorylation	EDEDDSKSISTPSAR CCCCCCCCCCCHHHH	26.23	20363803
1196	Phosphorylation	EDDSKSISTPSARRD CCCCCCCCCHHHHHH	41.16	30177828
1197	Phosphorylation	DDSKSISTPSARRDL CCCCCCCCHHHHHHH	21.42	20363803
1199	Phosphorylation	SKSISTPSARRDLAE CCCCCCHHHHHHHHH	34.20	30177828
1216	Phosphorylation	VMYMNNMSSPLTSRT HHHHHCCCCCCCCCC	30.81	29523821
1217	Phosphorylation	MYMNNMSSPLTSRTP HHHHCCCCCCCCCCC	17.11	29523821
1220	Phosphorylation	NNMSSPLTSRTPSID HCCCCCCCCCCCCCC	21.39	29523821
1221	Phosphorylation	NMSSPLTSRTPSIDL CCCCCCCCCCCCCCH	41.67	23532336
1223	Phosphorylation	SSPLTSRTPSIDLQR CCCCCCCCCCCCHHH	22.58	30266825
1225	Phosphorylation	PLTSRTPSIDLQRAC CCCCCCCCCCHHHHC	28.28	23401153
1240	Phosphorylation	DDKLNKKSPPLVKAC HHHHHCCCCHHHHHH	33.10	22617229
1250	Phosphorylation	LVKACRRSSLPPNSP HHHHHHHCCCCCCCC	19.51	23927012
1251	Phosphorylation	VKACRRSSLPPNSPK HHHHHHCCCCCCCCC	42.98	23927012
1256	Phosphorylation	RSSLPPNSPKPVRLT HCCCCCCCCCCCEEC	39.82	25159151
1265	Phosphorylation	KPVRLTKSKSYTKSE CCCEECCCCCCCCCC	22.92	26657352
1267	Phosphorylation	VRLTKSKSYTKSEEK CEECCCCCCCCCCCC	45.16	26657352
1268	Phosphorylation	RLTKSKSYTKSEEKP EECCCCCCCCCCCCC	23.17	26657352
1281	Phosphorylation	KPRDRLWSSPAFSPT CCCCCCCCCCCCCCC	30.91	19276368
1282	Phosphorylation	PRDRLWSSPAFSPTC CCCCCCCCCCCCCCC	14.52	28450419
1286	Phosphorylation	LWSSPAFSPTCPFRE CCCCCCCCCCCCCCC	22.77	27732954
1288	Phosphorylation	SSPAFSPTCPFREES CCCCCCCCCCCCCCC	31.45	27732954
1295	Phosphorylation	TCPFREESQDTLTHS CCCCCCCCCCCCCCC	28.71	25159151
1298	Phosphorylation	FREESQDTLTHSSPS CCCCCCCCCCCCCCC	26.39	28348404
1300	Phosphorylation	EESQDTLTHSSPSFN CCCCCCCCCCCCCCC	23.08	27080861
1302	Phosphorylation	SQDTLTHSSPSFNLD CCCCCCCCCCCCCCC	38.41	27080861
1303	Phosphorylation	QDTLTHSSPSFNLDT CCCCCCCCCCCCCCC	19.57	27080861
1305	Phosphorylation	TLTHSSPSFNLDTLL CCCCCCCCCCCCCCC	28.81	27251275
1310	Phosphorylation	SPSFNLDTLLVPKLD CCCCCCCCCCCCHHH	25.76	28348404
1315	Ubiquitination	LDTLLVPKLDVLRNS CCCCCCCHHHHHHHC	50.25	-
1322	Phosphorylation	KLDVLRNSMFTAGKG HHHHHHHCCCCCCCC	14.61	29083192
1325	Phosphorylation	VLRNSMFTAGKGVAE HHHHCCCCCCCCHHH	26.34	28555341
1328	Ubiquitination	NSMFTAGKGVAEKAS HCCCCCCCCHHHHHH	47.99	2190698
1330	Ubiquitination	MFTAGKGVAEKASKW CCCCCCCHHHHHHHH	7.67	21906983
1336	Acetylation	GVAEKASKWYSRFTM CHHHHHHHHHHCEEE	55.82	7432015
1338	Phosphorylation	AEKASKWYSRFTMYT HHHHHHHHHCEEEEE	8.16	-
1344	Phosphorylation	WYSRFTMYTTSSKDQ HHHCEEEEECCCCCC	12.10	-
1347	Phosphorylation	RFTMYTTSSKDQSSD CEEEEECCCCCCCCC	27.82	28555341
1348	Phosphorylation	FTMYTTSSKDQSSDR EEEEECCCCCCCCCC	37.85	28348404
1349	Ubiquitination	TMYTTSSKDQSSDRT EEEECCCCCCCCCCC	60.60	-
1356	Phosphorylation	KDQSSDRTSLSSVGA CCCCCCCCCHHHCCC	38.72	28270605
1357	Phosphorylation	DQSSDRTSLSSVGAQ CCCCCCCCHHHCCCC	27.44	28270605
1359	Phosphorylation	SSDRTSLSSVGAQDS CCCCCCHHHCCCCCC	23.81	28270605
1360	Phosphorylation	SDRTSLSSVGAQDSE CCCCCHHHCCCCCCC	29.84	28270605
1366	Phosphorylation	SSVGAQDSESTSLTD HHCCCCCCCCCCCCC	22.74	28270605
1368	Phosphorylation	VGAQDSESTSLTDED CCCCCCCCCCCCCHH	27.52	28270605
1369	Phosphorylation	GAQDSESTSLTDEDV CCCCCCCCCCCCHHH	24.57	28270605
1370	Phosphorylation	AQDSESTSLTDEDVC CCCCCCCCCCCHHHH	38.25	28270605
1372	Phosphorylation	DSESTSLTDEDVCHE CCCCCCCCCHHHHHH	36.79	28270605
1385	Phosphorylation	HELEGPISSQETSAT HHCCCCCCCCCCCCC	29.15	28270605
1386	Phosphorylation	ELEGPISSQETSATS HCCCCCCCCCCCCCC	32.52	28270605
1389	Phosphorylation	GPISSQETSATSGTK CCCCCCCCCCCCCCC	18.94	28270605
1401	Phosphorylation	GTKRIDLSRISLESS CCCEEECCEEEECCC	24.66	20068231
1404	Phosphorylation	RIDLSRISLESSASL EEECCEEEECCCCHH	25.60	20363803
1407	Phosphorylation	LSRISLESSASLEGS CCEEEECCCCHHCCC	36.18	20363803
1408	Phosphorylation	SRISLESSASLEGSL CEEEECCCCHHCCCH	16.70	20068231
1410	Phosphorylation	ISLESSASLEGSLSK EEECCCCHHCCCHHH	28.97	20363803
1414	Phosphorylation	SSASLEGSLSKFALP CCCHHCCCHHHCCCC	21.79	20068231
1416	Phosphorylation	ASLEGSLSKFALPGK CHHCCCHHHCCCCCC	27.68	20068231
1424	Phosphorylation	KFALPGKSEVTSSFN HCCCCCCCCCCCCCC	43.12	27080861
1427	Phosphorylation	LPGKSEVTSSFNASN CCCCCCCCCCCCCCC	18.01	27080861
1428	Phosphorylation	PGKSEVTSSFNASNT CCCCCCCCCCCCCCC	37.80	27080861
1429	Phosphorylation	GKSEVTSSFNASNTN CCCCCCCCCCCCCCC	17.10	27080861
1433	Phosphorylation	VTSSFNASNTNIFQN CCCCCCCCCCCCCHH	45.34	28270605
1435	Phosphorylation	SSFNASNTNIFQNYA CCCCCCCCCCCHHHH	27.48	28270605
1441	Phosphorylation	NTNIFQNYAMEVLIS CCCCCHHHHHHHHHH	9.13	27080861
1448	Phosphorylation	YAMEVLISSCSRCRT HHHHHHHHHCCCCCC	22.56	27080861
1449	Phosphorylation	AMEVLISSCSRCRTC HHHHHHHHCCCCCCC	14.76	27080861
1451	Phosphorylation	EVLISSCSRCRTCDC HHHHHHCCCCCCCCC	36.04	27080861
1504	Phosphorylation	DLRRPGRYFLKSSPS CCCCCCCEECCCCCC	21.12	29083192
1508	Phosphorylation	PGRYFLKSSPSTENM CCCEECCCCCCCCCC	50.02	25159151
1509	Phosphorylation	GRYFLKSSPSTENMH CCEECCCCCCCCCCC	22.68	25159151
1511	Phosphorylation	YFLKSSPSTENMHFP EECCCCCCCCCCCCC	50.75	25159151
1512	Phosphorylation	FLKSSPSTENMHFPS ECCCCCCCCCCCCCC	34.46	30278072
1519	Phosphorylation	TENMHFPSSISSQTR CCCCCCCCCCCHHHH	39.08	23403867
1520	Phosphorylation	ENMHFPSSISSQTRQ CCCCCCCCCCHHHHH	27.08	23403867
1522	Phosphorylation	MHFPSSISSQTRQSC CCCCCCCCHHHHHHH	20.52	23403867
1523	Phosphorylation	HFPSSISSQTRQSCI CCCCCCCHHHHHHHH	33.62	23403867
1525	Phosphorylation	PSSISSQTRQSCIST CCCCCHHHHHHHHHC	32.40	23403867
1531	Phosphorylation	QTRQSCISTSASGLD HHHHHHHHCCCCCCC	22.19	27080861
1532	Phosphorylation	TRQSCISTSASGLDT HHHHHHHCCCCCCCC	14.38	27080861
1533	Phosphorylation	RQSCISTSASGLDTS HHHHHHCCCCCCCCC	17.41	27080861
1535	Phosphorylation	SCISTSASGLDTSAL HHHHCCCCCCCCCCE	39.39	27080861
1539	Phosphorylation	TSASGLDTSALSVQG CCCCCCCCCCEEECC	22.42	27080861
1540	Phosphorylation	SASGLDTSALSVQGN CCCCCCCCCEEECCC	27.21	27080861
1543	Phosphorylation	GLDTSALSVQGNFDL CCCCCCEEECCCCCC	16.47	27080861
1554	Phosphorylation	NFDLNSKSKLQENFC CCCCCCCHHHHHCCC	38.12	20068231
1555	Ubiquitination	FDLNSKSKLQENFCT CCCCCCHHHHHCCCC	58.91	-
1562	Phosphorylation	KLQENFCTRSIQIPA HHHHCCCCCCEEECC	24.26	20068231
1564	Phosphorylation	QENFCTRSIQIPANR HHCCCCCCEEECCCC	10.74	20068231
1572	Phosphorylation	IQIPANRSKTAMSKC EEECCCCCCCCHHCC	33.88	20068231
1586	Methylation	CPIFPMARSISTSGP CCCCCCCCCCCCCCC	28.42	-
1587	Phosphorylation	PIFPMARSISTSGPL CCCCCCCCCCCCCCC	16.02	29255136
1589	Phosphorylation	FPMARSISTSGPLDK CCCCCCCCCCCCCCH	20.12	29255136
1590	Phosphorylation	PMARSISTSGPLDKE CCCCCCCCCCCCCHH	35.71	30266825
1591	Phosphorylation	MARSISTSGPLDKED CCCCCCCCCCCCHHH	31.46	30266825
1599	Phosphorylation	GPLDKEDTGRQKLIS CCCCHHHCCCCEEEE	35.04	23403867
1606	Phosphorylation	TGRQKLISTGSLPAT CCCCEEEECCCCCHH	36.83	26074081
1607	Phosphorylation	GRQKLISTGSLPATL CCCEEEECCCCCHHC	24.64	26074081
1609	Phosphorylation	QKLISTGSLPATLQG CEEEECCCCCHHCCC	31.13	26074081
1613	Phosphorylation	STGSLPATLQGATDS ECCCCCHHCCCCCCC	20.06	26074081
1765	Ubiquitination	SFNQELLKSMVKSIK CCCHHHHHHHHHHCH	49.48	-
1781	Phosphorylation	NDVYGPMSQILETLN CCCCCHHHHHHHHHH	19.73	22210691

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of MYCPP_HUMAN !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of MYCPP_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of MYCPP_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
SRTD1_HUMAN	SERTAD1	physical	20211142
TLX3_HUMAN	TLX3	physical	20211142
KCTD3_HUMAN	KCTD3	physical	27173435
KI13B_HUMAN	KIF13B	physical	27173435
ZBT21_HUMAN	ZBTB21	physical	27173435
KSR1_HUMAN	KSR1	physical	27173435
GGYF1_HUMAN	GIGYF1	physical	27173435
LRFN1_HUMAN	LRFN1	physical	27173435
CING_HUMAN	CGN	physical	27173435
DEN1A_HUMAN	DENND1A	physical	27173435
SPD2A_HUMAN	SH3PXD2A	physical	27173435
SRGP2_HUMAN	SRGAP2	physical	27173435
RTKN_HUMAN	RTKN	physical	27173435
MAST3_HUMAN	MAST3	physical	27173435
IF4E2_HUMAN	EIF4E2	physical	27173435
SI1L1_HUMAN	SIPA1L1	physical	27173435
PPM1H_HUMAN	PPM1H	physical	27173435
DEN4C_HUMAN	DENND4C	physical	27173435
LIMA1_HUMAN	LIMA1	physical	27173435
MAGI1_HUMAN	MAGI1	physical	27173435
TESK2_HUMAN	TESK2	physical	27173435
DCLK1_HUMAN	DCLK1	physical	27173435
ZN638_HUMAN	ZNF638	physical	27173435
HDAC4_HUMAN	HDAC4	physical	27173435
NF1_HUMAN	NF1	physical	27173435
SRS12_HUMAN	SRSF12	physical	27173435
CBY1_HUMAN	CBY1	physical	27173435
INP5E_HUMAN	INPP5E	physical	27173435

Drug and Disease Associations

Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of MYCPP_HUMAN

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"Quantitative phosphoproteomic analysis of T cell receptor signalingreveals system-wide modulation of protein-protein interactions."; Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K.,Rodionov V., Han D.K.; Sci. Signal. 2:RA46-RA46(2009). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1225, AND MASSSPECTROMETRY.	19690332 [Abstract]
"Lys-N and trypsin cover complementary parts of the phosphoproteome ina refined SCX-based approach."; Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J.,Mohammed S.; Anal. Chem. 81:4493-4501(2009). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-731; SER-1099; SER-1117AND SER-1225, AND MASS SPECTROMETRY.	19413330 [Abstract]
"A quantitative atlas of mitotic phosphorylation."; Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E.,Elledge S.J., Gygi S.P.; Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-728; SER-731 ANDSER-1587, AND MASS SPECTROMETRY.	18669648 [Abstract]
"Combining protein-based IMAC, peptide-based IMAC, and MudPIT forefficient phosphoproteomic analysis."; Cantin G.T., Yi W., Lu B., Park S.K., Xu T., Lee J.-D.,Yates J.R. III; J. Proteome Res. 7:1346-1351(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1281 AND SER-1511, ANDMASS SPECTROMETRY.	18220336 [Abstract]