CHC10_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: CHC10_HUMAN
• UniProt AC: Q8WYQ3
• Protein Name: Coiled-coil-helix-coiled-coil-helix domain-containing protein 10, mitochondrial
• Gene Name: CHCHD10
• Organism: Homo sapiens (Human).
• Sequence Length: 142
• Subcellular Localization: Mitochondrion intermembrane space . Enriched at the cristae junctions.
• Protein Description: May be involved in the maintenance of mitochondrial organization and mitochondrial cristae structure..
• Protein Sequence: MPRGSRSAASRPASRPAAPSAHPPAHPPPSAAAPAPAPSGQPGLMAQMATTAAGVAVGSAVGHVMGSALTGAFSGGSSEPSQPAVQQAPTPAAPQPLQMGPCAYEIRQFLDCSTTQSDLSLCEGFSEALKQCKYYHGLSSLP

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
133	Acetylation	SEALKQCKYYHGLSS HHHHHHCHHHHCCCC	46.48	27452117
139	Phosphorylation	CKYYHGLSSLP---- CHHHHCCCCCC----	34.13	28348404
140	Phosphorylation	KYYHGLSSLP----- HHHHCCCCCC-----	50.10	26852163
147	Phosphorylation	SLP------------ CCC------------		-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of CHC10_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of CHC10_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of CHC10_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
RNH1_HUMAN	RNASEH1	physical	27499296
CHC10_HUMAN	CHCHD10	physical	27499296
YMEL1_HUMAN	YME1L1	physical	27499296
STAR7_HUMAN	STARD7	physical	27499296
CLPX_HUMAN	CLPX	physical	27499296
CHCH2_HUMAN	CHCHD2	physical	27499296
CX6A1_HUMAN	COX6A1	physical	27499296
ADT3_HUMAN	SLC25A6	physical	27499296
TIM44_HUMAN	TIMM44	physical	27499296
OXA1L_HUMAN	OXA1L	physical	27499296
GHITM_HUMAN	GHITM	physical	27499296
TXTP_HUMAN	SLC25A1	physical	27499296
USMG5_HUMAN	USMG5	physical	27499296
MIC60_HUMAN	IMMT	physical	27499296
STML2_HUMAN	STOML2	physical	27499296
COX6C_HUMAN	COX6C	physical	27499296
PDIP2_HUMAN	POLDIP2	physical	27499296
CX7A2_HUMAN	COX7A2	physical	27499296
MTCH2_HUMAN	MTCH2	physical	27499296
TIM50_HUMAN	TIMM50	physical	27499296
C1QBP_HUMAN	C1QBP	physical	27499296
COA3_HUMAN	COA3	physical	27499296
RM23_HUMAN	MRPL23	physical	27499296
NDUS3_HUMAN	NDUFS3	physical	27499296
ECH1_HUMAN	ECH1	physical	27499296
ATP5H_HUMAN	ATP5H	physical	27499296
NB5R3_HUMAN	CYB5R3	physical	27499296
PREP_HUMAN	PITRM1	physical	27499296
GLRX5_HUMAN	GLRX5	physical	27499296
MCCA_HUMAN	MCCC1	physical	27499296
NDUA5_HUMAN	NDUFA5	physical	27499296
AT5F1_HUMAN	ATP5F1	physical	27499296
SFXN1_HUMAN	SFXN1	physical	27499296
ATPG_HUMAN	ATP5C1	physical	27499296
CLPB_HUMAN	CLPB	physical	27499296
NDUA8_HUMAN	NDUFA8	physical	27499296
MOT1_HUMAN	SLC16A1	physical	27499296
MIA40_HUMAN	CHCHD4	physical	27499296
ATPO_HUMAN	ATP5O	physical	27499296
EFHD1_HUMAN	EFHD1	physical	27499296
COX5A_HUMAN	COX5A	physical	27499296
BNC2_HUMAN	BNC2	physical	28514442
ZN579_HUMAN	ZNF579	physical	28514442
RBM26_HUMAN	RBM26	physical	28514442
RBM27_HUMAN	RBM27	physical	28514442
BAG1_HUMAN	BAG1	physical	28514442
RBM23_HUMAN	RBM23	physical	28514442
ZFP91_HUMAN	ZFP91	physical	28514442
PHF10_HUMAN	PHF10	physical	28514442
PRC2A_HUMAN	PRRC2A	physical	28514442
C1QBP_HUMAN	C1QBP	physical	28514442
KLF13_HUMAN	KLF13	physical	28514442
ZN444_HUMAN	ZNF444	physical	28514442
FAF1_HUMAN	FAF1	physical	28514442
CATIN_HUMAN	CACTIN	physical	28514442
DHX8_HUMAN	DHX8	physical	28514442
CLPX_HUMAN	CLPX	physical	28514442
CARME_HUMAN	C9orf41	physical	28514442
FIZ1_HUMAN	FIZ1	physical	28514442
LUC7L_HUMAN	LUC7L	physical	28514442
CHTOP_HUMAN	CHTOP	physical	28514442
AT8B2_HUMAN	ATP8B2	physical	28514442
NEUA_HUMAN	CMAS	physical	28514442
TR150_HUMAN	THRAP3	physical	28514442
LS14B_HUMAN	LSM14B	physical	28514442
PRC2C_HUMAN	PRRC2C	physical	28514442
SREK1_HUMAN	SREK1	physical	28514442
U2AF2_HUMAN	U2AF2	physical	28514442
RRP12_HUMAN	RRP12	physical	28514442
TRPM3_HUMAN	TRPM3	physical	28514442
ZN593_HUMAN	ZNF593	physical	28514442

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.