dbPTM

PRC2C_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	PRC2C_HUMAN
UniProt AC	Q9Y520
Protein Name	Protein PRRC2C
Gene Name	PRRC2C
Organism	Homo sapiens (Human).
Sequence Length	2896
Subcellular Localization
Protein Description
Protein Sequence	MSEKSGQSTKAKDGKKYATLSLFNTYKGKSLETQKTTARHGLQSLGKVGISRRMPPPANLPSLKAENKGNDPNVNIVPKDGTGWASKQEQHEEEKTPEVPPAQPKPGVAAPPEVAPAPKSWASNKQGGQGDGIQVNSQFQQEFPSLQAAGDQEKKEKETNDDNYGPGPSLRPPNVACWRDGGKAAGSPSSSDQDEKLPGQDESTAGTSEQNDILKVVEKRIACGPPQAKLNGQQAALASQYRAMMPPYMFQQYPRMTYPPLHGPMRFPPSLSETNKGLRGRGPPPSWASEPERPSILSASELKELDKFDNLDAEADEGWAGAQMEVDYTEQLNFSDDDEQGSNSPKENNSEDQGSKASENNENKKETDEVSNTKSSSQIPAQPSVAKVPYGKGPSFNQERGTSSHLPPPPKLLAQQHPPPDRQAVPGRPGPFPSKQQVADEDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGILEKQPSPEEIREREREKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREMEKERKQEKEKELERQKEKEKELQKMKEQEKECELEKEREKLEEKIEPREPNLEPMVEKQESENSCNKEEEPVFTRQDSNRSEKEATPVVHETEPESGSQPRPAVLSGYFKQFQKSLPPRFQRQQEQMKQQQWQQQQQQGVLPQTVPSQPSSSTVPPPPHRPLYQPMQPHPQHLASMGFDPRWLMMQSYMDPRMMSGRPAMDIPPIHPGMIPPKPLMRRDQMEGSPNSSESFEHIARSARDHAISLSEPRMLWGSDPYPHAEPQQATTPKATEEPEDVRSEAALDQEQITAAYSVEHNQLEAHPKADFIRESSEAQVQKFLSRSVEDVRPHHTDANNQSACFEAPDQKTLSAPQEERISAVESQPSRKRSVSHGSNHTQKPDEQRSEPSAGIPKVTSRCIDSKEPIERPEEKPKKEGFIRSSEGPKPEKVYKSKSETRWGPRPSSNRREEVNDRPVRRSGPIKKPVLRDMKEEREQRKEKEGEKAEKVTEKVVVKPEKTEKKDLPPPPPPPQPPAPIQPQSVPPPIQPEAEKFPSTETATLAQKPSQDTEKPLEPVSTVQVEPAVKTVNQQTMAAPVVKEEKQPEKVISKDLVIERPRPDSRPAVKKESTLPPRTYWKEARERDWFPDQGYRGRGRGEYYSRGRSYRGSYGGRGRGGRGHTRDYPQYRDNKPRAEHIPSGPLRQREESETRSESSDFEVVPKRRRQRGSETDTDSEIHESASDKDSLSKGKLPKREERPENKKPVKPHSSFKPDNHVRIDNRLLEKPYVRDDDKAKPGFLPKGEPTRRGRGGTFRRGGRDPGGRPSRPSTLRRPAYRDNQWNPRQSEVPKPEDGEPPRRHEQFIPIAADKRPPKFERKFDPARERPRRQRPTRPPRQDKPPRFRRLREREAASKSNEVVAVPTNGTVNNVAQEPVNTLGDISGNKTPDLSNQNSSDQANEEWETASESSDFNERRERDEKKNADLNAQTVVKVGENVLPPKREIAKRSFSSQRPVDRQNRRGNNGPPKSGRNFSGPRNERRSGPPSKSGKRGPFDDQPAGTTGVDLINGSSAHHQEGVPNGTGQKNSKDSTGKKREDPKPGPKKPKEKVDALSQFDLNNYASVVIIDDHPEVTVIEDPQSNLNDDGFTEVVSKKQQKRLQDEERRKKEEQVIQVWNKKNANEKGRSQTSKLPPRFAKKQATGIQQAQSSASVPPLASAPLPPSTSASVPASTSAPLPATLTPVPASTSAPVPASTLAPVLASTSAPVPASPLAPVSASASVSASVPASTSAAAITSSSAPASAPAPTPILASVSTPASVTILASASIPILASALASTSAPTPAPAASSPAAPVITAPTIPASAPTASVPLAPASASAPAPAPTPVSAPNPAPPAPAQTQAQTHKPVQNPLQTTSQSSKQPPPSIRLPSAQTPNGTDYVASGKSIQTPQSHGTLTAELWDNKVAPPAVLNDISKKLGPISPPQPPSVSAWNKPLTSFGSAPSSEGAKNGQESGLEIGTDTIQFGAPASNGNENEVVPVLSEKSADKIPEPKEQRQKQPRAGPIKAQKLPDLSPVENKEHKPGPIGKERSLKNRKVKDAQQVEPEGQEKPSPATVRSTDPVTTKETKAVSEMSTEIGTMISVSSAEYGTNAKESVTDYTTPSSSLPNTVATNNTKMEDTLVNNVPLPNTLPLPKRETIQQSSSLTSVPPTTFSLTFKMESARKAWENSPNVREKGSPVTSTAPPIATGVSSSASGPSTANYNSFSSASMPQIPVASVTPTASLSGAGTYTTSSLSTKSTTTSDPPNICKVKPQQLQTSSLPSASHFSQLSCMPSLIAQQQQNPQVYVSQSAAAQIPAFYMDTSHLFNTQHARLAPPSLAQQQGFQPGLSQPTSVQQIPIPIYAPLQGQHQAQLSLGAGPAVSQAQELFSSSLQPYRSQPAFMQSSLSQPSVVLSGTAIHNFPTVQHQELAKAQSGLAFQQTSNTQPIPILYEHQLGQASGLGGSQLIDTHLLQARANLTQASNLYSGQVQQPGQTNFYNTAQSPSALQQVTVPLPASQLSLPNFGSTGQPLIALPQTLQPPLQHTTPQAQAQSLSRPAQVSQPFRGLIPAGTQHSMIATTGKMSEMELKAFGSGIDIKPGTPPIAGRSTTPTSSPFRATSTSPNSQSSKMNSIVYQKQFQSAPATVRMTQPFPTQFAPQILSQPNLVPPLVRAPHTNTFPAPVQRPPMALASQMPPPLTTGLMSHARLPHVARGPCGSLSGVRGNQAQAALKAEQDMKAKQRAEVLQSTQRFFSEQQQSKQIGGGKAQKVDSDSSKPPETLTDPPGVCQEKVEEKPPPAPSIATKPVRTGPIKPQAIKTEETKS

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	O-linked_Glycosylation	------MSEKSGQST ------CCCCCCCCC	66.10	32574038
9	Phosphorylation	SEKSGQSTKAKDGKK CCCCCCCCCCCCCCE	27.42	-
17	Phosphorylation	KAKDGKKYATLSLFN CCCCCCEEEEEEEEE	14.33	25394399
19	Phosphorylation	KDGKKYATLSLFNTY CCCCEEEEEEEEECC	17.50	25106551
21	Phosphorylation	GKKYATLSLFNTYKG CCEEEEEEEEECCCC	26.93	28857561
25	Phosphorylation	ATLSLFNTYKGKSLE EEEEEEECCCCCCCC	21.19	24173317
26	Phosphorylation	TLSLFNTYKGKSLET EEEEEECCCCCCCCH	20.88	-
27	Acetylation	LSLFNTYKGKSLETQ EEEEECCCCCCCCHH	58.80	19608861
27	Methylation	LSLFNTYKGKSLETQ EEEEECCCCCCCCHH	58.80	90533
29	Methylation	LFNTYKGKSLETQKT EEECCCCCCCCHHHH	47.95	115975801
44	Phosphorylation	TARHGLQSLGKVGIS HHHHHHHHHCCCCCC	44.10	25159151
47	Acetylation	HGLQSLGKVGISRRM HHHHHHCCCCCCCCC	42.45	23954790
51	Phosphorylation	SLGKVGISRRMPPPA HHCCCCCCCCCCCCC	14.12	28258704
53	Methylation	GKVGISRRMPPPANL CCCCCCCCCCCCCCC	34.86	-
62	Phosphorylation	PPPANLPSLKAENKG CCCCCCCHHCCCCCC	45.74	28258704
96	Phosphorylation	EQHEEEKTPEVPPAQ HHCCCCCCCCCCCCC	28.14	25159151
120	Phosphorylation	EVAPAPKSWASNKQG CCCCCCCHHHCCCCC	27.15	24719451
137	Phosphorylation	GDGIQVNSQFQQEFP CCCCCCCHHHHHHCC	33.25	27251275
145	Phosphorylation	QFQQEFPSLQAAGDQ HHHHHCCHHHCCCCH	38.13	28555341
159	Phosphorylation	QEKKEKETNDDNYGP HHHHHHHCCCCCCCC	55.82	21945579
164	Phosphorylation	KETNDDNYGPGPSLR HHCCCCCCCCCCCCC	31.52	21945579
166 (in isoform 7)	Phosphorylation	-	40.96	27642862
169	Phosphorylation	DNYGPGPSLRPPNVA CCCCCCCCCCCCCEE	42.81	21945579
187	Phosphorylation	DGGKAAGSPSSSDQD CCCCCCCCCCCCCCC	19.51	29255136
189	Phosphorylation	GKAAGSPSSSDQDEK CCCCCCCCCCCCCCC	44.14	29255136
190	Phosphorylation	KAAGSPSSSDQDEKL CCCCCCCCCCCCCCC	41.12	29255136
191	Phosphorylation	AAGSPSSSDQDEKLP CCCCCCCCCCCCCCC	43.56	22167270
196	Acetylation	SSSDQDEKLPGQDES CCCCCCCCCCCCCCC	69.17	26051181
203	Phosphorylation	KLPGQDESTAGTSEQ CCCCCCCCCCCCHHH	31.67	23927012
204	Phosphorylation	LPGQDESTAGTSEQN CCCCCCCCCCCHHHC	27.36	23927012
207	Phosphorylation	QDESTAGTSEQNDIL CCCCCCCCHHHCHHH	26.99	23927012
208	Phosphorylation	DESTAGTSEQNDILK CCCCCCCHHHCHHHH	35.95	23927012
241	Phosphorylation	QAALASQYRAMMPPY HHHHHHHHHHHCCHH	9.61	25839225
242	Asymmetric dimethylarginine	AALASQYRAMMPPYM HHHHHHHHHHCCHHH	14.36	-
242	Methylation	AALASQYRAMMPPYM HHHHHHHHHHCCHHH	14.36	24129315
243 (in isoform 7)	Phosphorylation	-	8.16	27642862
253	Phosphorylation	PPYMFQQYPRMTYPP CHHHHCCCCCCCCCC	5.09	-
255	Asymmetric dimethylarginine	YMFQQYPRMTYPPLH HHHCCCCCCCCCCCC	25.74	-
255	Methylation	YMFQQYPRMTYPPLH HHHCCCCCCCCCCCC	25.74	24129315
266	Asymmetric dimethylarginine	PPLHGPMRFPPSLSE CCCCCCCCCCCCHHH	44.01	-
266	Methylation	PPLHGPMRFPPSLSE CCCCCCCCCCCCHHH	44.01	24129315
279	Methylation	SETNKGLRGRGPPPS HHCCCCCCCCCCCCC	41.24	24129315
281	Methylation	TNKGLRGRGPPPSWA CCCCCCCCCCCCCCC	48.27	24129315
289	Phosphorylation	GPPPSWASEPERPSI CCCCCCCCCCCCCCC	47.64	28348404
293	Methylation	SWASEPERPSILSAS CCCCCCCCCCCCCHH	40.77	54554663
335	Phosphorylation	YTEQLNFSDDDEQGS EEECCCCCCCCCCCC	38.77	22468782
344	Phosphorylation	DDEQGSNSPKENNSE CCCCCCCCCCCCCCC	38.76	24275569
355	Phosphorylation	NNSEDQGSKASENNE CCCCCCCCCCHHCCC	21.29	23532336
375	Phosphorylation	DEVSNTKSSSQIPAQ CCCCCCCCCCCCCCC	32.93	25627689
376	Phosphorylation	EVSNTKSSSQIPAQP CCCCCCCCCCCCCCC	28.02	25159151
377	Phosphorylation	VSNTKSSSQIPAQPS CCCCCCCCCCCCCCC	38.94	25159151
384	Phosphorylation	SQIPAQPSVAKVPYG CCCCCCCCCEECCCC	23.72	27362937
390	Phosphorylation	PSVAKVPYGKGPSFN CCCEECCCCCCCCCC	34.16	29978859
392	Acetylation	VAKVPYGKGPSFNQE CEECCCCCCCCCCCC	62.90	19608861
392	Methylation	VAKVPYGKGPSFNQE CEECCCCCCCCCCCC	62.90	22645459
395	Phosphorylation	VPYGKGPSFNQERGT CCCCCCCCCCCCCCC	45.56	28102081
400	Methylation	GPSFNQERGTSSHLP CCCCCCCCCCCCCCC	43.88	115489187
402	Phosphorylation	SFNQERGTSSHLPPP CCCCCCCCCCCCCCC	33.02	28348404
403	Phosphorylation	FNQERGTSSHLPPPP CCCCCCCCCCCCCCH	20.70	28348404
404	Phosphorylation	NQERGTSSHLPPPPK CCCCCCCCCCCCCHH	28.96	28348404
411	Acetylation	SHLPPPPKLLAQQHP CCCCCCHHHHHCCCC	63.00	26051181
422	Methylation	QQHPPPDRQAVPGRP CCCCCCCCCCCCCCC	31.93	115368793
422 (in isoform 2)	Ubiquitination	-	31.93	21890473
435	Acetylation	RPGPFPSKQQVADED CCCCCCCHHHCCCHH	45.01	25953088
435	Methylation	RPGPFPSKQQVADED CCCCCCCHHHCCCHH	45.01	72599489
453	Phosphorylation	KQRRRQQSEISAAVE HHHHHHHHHHHHHHH	28.67	21815630
456	Phosphorylation	RRQQSEISAAVERAR HHHHHHHHHHHHHHH	13.21	20068231
484	Acetylation	RKAACAEKLKRLDEK HHHHHHHHHHHHHHH	40.56	26051181
497	Acetylation	EKLGILEKQPSPEEI HHHCHHCCCCCHHHH	65.15	26051181
500	Phosphorylation	GILEKQPSPEEIRER CHHCCCCCHHHHHHH	42.31	23401153
585	Acetylation	QKMKEQEKECELEKE HHHHHHHHHHHHHHH	68.32	26051181
616	Phosphorylation	PMVEKQESENSCNKE HHHCHHHCCCCCCCC	39.31	23882029
619	Phosphorylation	EKQESENSCNKEEEP CHHHCCCCCCCCCCC	18.27	23882029
622	Acetylation	ESENSCNKEEEPVFT HCCCCCCCCCCCCCC	71.48	26051181
629	Phosphorylation	KEEEPVFTRQDSNRS CCCCCCCCCCCCCCC	27.88	30576142
630 (in isoform 2)	Ubiquitination	-	27.18	21890473
633	Phosphorylation	PVFTRQDSNRSEKEA CCCCCCCCCCCCCCC	26.29	27273156
636	Phosphorylation	TRQDSNRSEKEATPV CCCCCCCCCCCCCCC	58.22	26503892
641	Phosphorylation	NRSEKEATPVVHETE CCCCCCCCCCCCCCC	20.08	25159151
647	Phosphorylation	ATPVVHETEPESGSQ CCCCCCCCCCCCCCC	41.80	22199227
651	Phosphorylation	VHETEPESGSQPRPA CCCCCCCCCCCCCHH	55.23	25159151
653	Phosphorylation	ETEPESGSQPRPAVL CCCCCCCCCCCHHHH	46.41	25159151
661	Phosphorylation	QPRPAVLSGYFKQFQ CCCHHHHHHHHHHHH	25.50	27251275
663	Phosphorylation	RPAVLSGYFKQFQKS CHHHHHHHHHHHHHH	12.29	-
665	Ubiquitination	AVLSGYFKQFQKSLP HHHHHHHHHHHHHCC	41.54	21890473
665 (in isoform 1)	Ubiquitination	-	41.54	21890473
665 (in isoform 4)	Ubiquitination	-	41.54	21890473
665 (in isoform 5)	Ubiquitination	-	41.54	21890473
665 (in isoform 6)	Ubiquitination	-	41.54	21890473
666 (in isoform 3)	Ubiquitination	-	35.78	21890473
667 (in isoform 7)	Ubiquitination	-	11.57	21890473
669	Ubiquitination	GYFKQFQKSLPPRFQ HHHHHHHHHCCHHHH	56.07	-
670	Phosphorylation	YFKQFQKSLPPRFQR HHHHHHHHCCHHHHH	35.01	24719451
671 (in isoform 7)	Ubiquitination	-	9.73	-
742	Phosphorylation	PRWLMMQSYMDPRMM HHHHHHHHHCCHHHC	12.43	29978859
743	Phosphorylation	RWLMMQSYMDPRMMS HHHHHHHHCCHHHCC	6.66	29978859
747	Methylation	MQSYMDPRMMSGRPA HHHHCCHHHCCCCCC	29.22	24411025
776	Sulfoxidation	PLMRRDQMEGSPNSS CCCCHHHCCCCCCCH	8.04	21406390
779	O-linked_Glycosylation	RRDQMEGSPNSSESF CHHHCCCCCCCHHHH	13.96	32574038
779	Phosphorylation	RRDQMEGSPNSSESF CHHHCCCCCCCHHHH	13.96	29255136
782	Phosphorylation	QMEGSPNSSESFEHI HCCCCCCCHHHHHHH	38.58	30266825
783	Phosphorylation	MEGSPNSSESFEHIA CCCCCCCHHHHHHHH	43.85	22167270
785	Phosphorylation	GSPNSSESFEHIARS CCCCCHHHHHHHHHH	37.57	23927012
799	Phosphorylation	SARDHAISLSEPRML HHHHHCCCCCCCCCC	26.99	23401153
801	Phosphorylation	RDHAISLSEPRMLWG HHHCCCCCCCCCCCC	38.47	29255136
804	Methylation	AISLSEPRMLWGSDP CCCCCCCCCCCCCCC	28.86	115489179
809	Phosphorylation	EPRMLWGSDPYPHAE CCCCCCCCCCCCCCC	24.67	28450419
812	Phosphorylation	MLWGSDPYPHAEPQQ CCCCCCCCCCCCCCC	16.79	22617229
821	Phosphorylation	HAEPQQATTPKATEE CCCCCCCCCCCCCCC	39.01	25159151
822	Phosphorylation	AEPQQATTPKATEEP CCCCCCCCCCCCCCC	26.30	25159151
826	Phosphorylation	QATTPKATEEPEDVR CCCCCCCCCCCHHHH	47.19	22210691
833	Methylation	TEEPEDVRSEAALDQ CCCCHHHHHHHHCCH	40.89	115489171
834	Phosphorylation	EEPEDVRSEAALDQE CCCHHHHHHHHCCHH	31.28	22210691
844	Phosphorylation	ALDQEQITAAYSVEH HCCHHHHHHHHHHHC	12.62	28796482
847	Phosphorylation	QEQITAAYSVEHNQL HHHHHHHHHHHCCCC	15.70	28796482
848	Phosphorylation	EQITAAYSVEHNQLE HHHHHHHHHHCCCCC	19.12	28796482
866	Phosphorylation	KADFIRESSEAQVQK CCHHHHCCCHHHHHH	24.51	28857561
867	Phosphorylation	ADFIRESSEAQVQKF CHHHHCCCHHHHHHH	32.00	29083192
873	Ubiquitination	SSEAQVQKFLSRSVE CCHHHHHHHHHCCHH	49.79	21890473
873 (in isoform 1)	Ubiquitination	-	49.79	21890473
873 (in isoform 4)	Ubiquitination	-	49.79	21890473
873 (in isoform 5)	Ubiquitination	-	49.79	21890473
873 (in isoform 6)	Ubiquitination	-	49.79	21890473
874 (in isoform 3)	Ubiquitination	-	4.13	21890473
875 (in isoform 7)	Ubiquitination	-	5.53	21890473
876	Phosphorylation	AQVQKFLSRSVEDVR HHHHHHHHCCHHHHC	26.16	23401153
878	Phosphorylation	VQKFLSRSVEDVRPH HHHHHHCCHHHHCCC	26.87	29255136
887	Phosphorylation	EDVRPHHTDANNQSA HHHCCCCCCCCCCCC	33.50	29255136
893	Phosphorylation	HTDANNQSACFEAPD CCCCCCCCCCEECCC	29.18	26503892
905	Phosphorylation	APDQKTLSAPQEERI CCCCCCCCCCHHHHH	43.04	24245541
913	Phosphorylation	APQEERISAVESQPS CCHHHHHHHHHCCCC	32.27	23186163
917	Phosphorylation	ERISAVESQPSRKRS HHHHHHHCCCCCCCC	40.57	23403867
920	Phosphorylation	SAVESQPSRKRSVSH HHHHCCCCCCCCCCC	42.68	25262027
924	Phosphorylation	SQPSRKRSVSHGSNH CCCCCCCCCCCCCCC	30.89	20201521
926	Phosphorylation	PSRKRSVSHGSNHTQ CCCCCCCCCCCCCCC	24.31	20201521
929	Phosphorylation	KRSVSHGSNHTQKPD CCCCCCCCCCCCCCH	21.73	20201521
932	Phosphorylation	VSHGSNHTQKPDEQR CCCCCCCCCCCHHHC	42.40	23927012
940	Phosphorylation	QKPDEQRSEPSAGIP CCCHHHCCCCCCCCC	54.26	23186163
943	Phosphorylation	DEQRSEPSAGIPKVT HHHCCCCCCCCCHHH	34.77	23186163
975	Phosphorylation	KKEGFIRSSEGPKPE CCCCCCCCCCCCCCC	28.11	28555341
976	Phosphorylation	KEGFIRSSEGPKPEK CCCCCCCCCCCCCCH	36.40	28555341
985	Phosphorylation	GPKPEKVYKSKSETR CCCCCHHCCCCCCCC	22.17	27155012
998	Phosphorylation	TRWGPRPSSNRREEV CCCCCCCCCCCCHHH	46.61	23186163
999	Phosphorylation	RWGPRPSSNRREEVN CCCCCCCCCCCHHHC	36.72	23917254
1013	Phosphorylation	NDRPVRRSGPIKKPV CCCCCCCCCCCCCHH	38.05	24732914
1017	Acetylation	VRRSGPIKKPVLRDM CCCCCCCCCHHHHHH	54.91	25953088
1034	Ubiquitination	EREQRKEKEGEKAEK HHHHHHHHHHHHHHH	74.24	-
1041	Acetylation	KEGEKAEKVTEKVVV HHHHHHHHCCEEEEE	60.35	19828799
1041	Ubiquitination	KEGEKAEKVTEKVVV HHHHHHHHCCEEEEE	60.35	-
1045	Acetylation	KAEKVTEKVVVKPEK HHHHCCEEEEECCCC	30.85	19828811
1049	Acetylation	VTEKVVVKPEKTEKK CCEEEEECCCCCCCC	35.53	19828823
1089	Phosphorylation	PEAEKFPSTETATLA CCHHCCCCCCCCCCC	41.84	21406692
1090	Phosphorylation	EAEKFPSTETATLAQ CHHCCCCCCCCCCCC	37.28	21406692
1092	Phosphorylation	EKFPSTETATLAQKP HCCCCCCCCCCCCCC	25.65	21406692
1094	Phosphorylation	FPSTETATLAQKPSQ CCCCCCCCCCCCCCC	30.00	21406692
1100	Phosphorylation	ATLAQKPSQDTEKPL CCCCCCCCCCCCCCC	47.96	25159151
1103	Phosphorylation	AQKPSQDTEKPLEPV CCCCCCCCCCCCCCC	37.97	21406692
1121	Phosphorylation	QVEPAVKTVNQQTMA EEECCCCCCCCCCCC	20.35	18452278
1127	Sulfoxidation	KTVNQQTMAAPVVKE CCCCCCCCCCCCCCC	2.32	21406390
1133	Sumoylation	TMAAPVVKEEKQPEK CCCCCCCCCCCCCCC	61.46	-
1133	Sumoylation	TMAAPVVKEEKQPEK CCCCCCCCCCCCCCC	61.46	28112733
1133	Ubiquitination	TMAAPVVKEEKQPEK CCCCCCCCCCCCCCC	61.46	-
1155	Phosphorylation	IERPRPDSRPAVKKE EECCCCCCCCCCCCC	42.73	28985074
1163	Phosphorylation	RPAVKKESTLPPRTY CCCCCCCCCCCCCCC	44.09	23401153
1164	Phosphorylation	PAVKKESTLPPRTYW CCCCCCCCCCCCCCH	44.36	24719451
1170	Phosphorylation	STLPPRTYWKEARER CCCCCCCCHHHHHHC	18.76	24719451
1172	Methylation	LPPRTYWKEARERDW CCCCCCHHHHHHCCC	30.96	115975793
1174 (in isoform 7)	Ubiquitination	-	18.20	-
1186	Methylation	WFPDQGYRGRGRGEY CCCCCCCCCCCCCCC	34.85	26495047
1188	Methylation	PDQGYRGRGRGEYYS CCCCCCCCCCCCCCC	23.72	24383315
1190	Methylation	QGYRGRGRGEYYSRG CCCCCCCCCCCCCCC	33.15	24383327
1196	Methylation	GRGEYYSRGRSYRGS CCCCCCCCCCCCCCC	28.55	24383339
1198	Methylation	GEYYSRGRSYRGSYG CCCCCCCCCCCCCCC	29.42	54554679
1215	Phosphorylation	GRGGRGHTRDYPQYR CCCCCCCCCCCCCCC	28.23	28152594
1218	Phosphorylation	GRGHTRDYPQYRDNK CCCCCCCCCCCCCCC	6.74	27273156
1221	Phosphorylation	HTRDYPQYRDNKPRA CCCCCCCCCCCCCCH	18.54	28152594
1233	O-linked_Glycosylation	PRAEHIPSGPLRQRE CCHHCCCCCCCCCCC	53.06	32574038
1233	Phosphorylation	PRAEHIPSGPLRQRE CCHHCCCCCCCCCCC	53.06	27273156
1242	Phosphorylation	PLRQREESETRSESS CCCCCCCCCCCCCCC	39.24	25463755
1244	Phosphorylation	RQREESETRSESSDF CCCCCCCCCCCCCCC	49.10	25463755
1246	Phosphorylation	REESETRSESSDFEV CCCCCCCCCCCCCEE	49.61	29255136
1248	Phosphorylation	ESETRSESSDFEVVP CCCCCCCCCCCEECC	36.13	29255136
1249	Phosphorylation	SETRSESSDFEVVPK CCCCCCCCCCEECCC	42.12	29255136
1263	Phosphorylation	KRRRQRGSETDTDSE CHHHCCCCCCCCHHH	39.24	23927012
1265	Phosphorylation	RRQRGSETDTDSEIH HHCCCCCCCCHHHHH	45.99	30278072
1267	Phosphorylation	QRGSETDTDSEIHES CCCCCCCCHHHHHHC	49.17	23927012
1269	Phosphorylation	GSETDTDSEIHESAS CCCCCCHHHHHHCCC	40.31	23927012
1274	Phosphorylation	TDSEIHESASDKDSL CHHHHHHCCCCCCHH	20.93	23927012
1276	Phosphorylation	SEIHESASDKDSLSK HHHHHCCCCCCHHCC	55.24	23927012
1280	O-linked_Glycosylation	ESASDKDSLSKGKLP HCCCCCCHHCCCCCC	40.04	32574038
1280	Phosphorylation	ESASDKDSLSKGKLP HCCCCCCHHCCCCCC	40.04	23927012
1282	O-linked_Glycosylation	ASDKDSLSKGKLPKR CCCCCHHCCCCCCCC	43.23	32574038
1282	Phosphorylation	ASDKDSLSKGKLPKR CCCCCHHCCCCCCCC	43.23	23663014
1303	Phosphorylation	KKPVKPHSSFKPDNH CCCCCCCCCCCCCCC	46.10	28555341
1320	Malonylation	IDNRLLEKPYVRDDD ECCCHHCCCCCCCCC	41.43	26320211
1322 (in isoform 7)	Malonylation	-	21.13	26320211
1342	Dimethylation	PKGEPTRRGRGGTFR CCCCCCCCCCCCCCC	41.46	-
1342	Methylation	PKGEPTRRGRGGTFR CCCCCCCCCCCCCCC	41.46	54547883
1344	Dimethylation	GEPTRRGRGGTFRRG CCCCCCCCCCCCCCC	38.26	-
1344	Methylation	GEPTRRGRGGTFRRG CCCCCCCCCCCCCCC	38.26	54547889
1350	Methylation	GRGGTFRRGGRDPGG CCCCCCCCCCCCCCC	47.96	54554647
1353	Methylation	GTFRRGGRDPGGRPS CCCCCCCCCCCCCCC	50.18	54554655
1358	Methylation	GGRDPGGRPSRPSTL CCCCCCCCCCCCCCC	31.75	54554671
1360	Phosphorylation	RDPGGRPSRPSTLRR CCCCCCCCCCCCCCC	56.30	23312004
1363	Phosphorylation	GGRPSRPSTLRRPAY CCCCCCCCCCCCCCC	38.68	20068231
1364	Phosphorylation	GRPSRPSTLRRPAYR CCCCCCCCCCCCCCC	27.28	23917254
1367	Methylation	SRPSTLRRPAYRDNQ CCCCCCCCCCCCCCC	24.26	115489211
1380	Phosphorylation	NQWNPRQSEVPKPED CCCCCCCCCCCCCCC	41.67	28555341
1449	Phosphorylation	EREAASKSNEVVAVP HHHHHHCCCCEEEEC	35.41	22199227
1457	Phosphorylation	NEVVAVPTNGTVNNV CCEEEECCCCCCCCC	39.42	20068231
1460	Phosphorylation	VAVPTNGTVNNVAQE EEECCCCCCCCCCCC	23.33	20068231
1471	Phosphorylation	VAQEPVNTLGDISGN CCCCCCCCCHHCCCC	32.14	30619164
1476	Phosphorylation	VNTLGDISGNKTPDL CCCCHHCCCCCCCCC	40.84	22199227
1480	Phosphorylation	GDISGNKTPDLSNQN HHCCCCCCCCCCCCC	26.49	22115753
1484	Phosphorylation	GNKTPDLSNQNSSDQ CCCCCCCCCCCCCHH	43.69	22115753
1488	Phosphorylation	PDLSNQNSSDQANEE CCCCCCCCCHHHHHH	26.06	21406692
1489	Phosphorylation	DLSNQNSSDQANEEW CCCCCCCCHHHHHHH	41.09	28450419
1498	Phosphorylation	QANEEWETASESSDF HHHHHHHHHHHCCCH	36.23	22115753
1500	Phosphorylation	NEEWETASESSDFNE HHHHHHHHHCCCHHH	45.49	22115753
1502	Phosphorylation	EWETASESSDFNERR HHHHHHHCCCHHHHH	32.48	22115753
1503	Phosphorylation	WETASESSDFNERRE HHHHHHCCCHHHHHH	42.01	22115753
1523	Phosphorylation	NADLNAQTVVKVGEN CCCCCCHHHEEECCC	25.51	20068231
1542	Phosphorylation	KREIAKRSFSSQRPV HHHHHHHHCCCCCCC	28.86	23401153
1544	Phosphorylation	EIAKRSFSSQRPVDR HHHHHHCCCCCCCCC	27.14	29255136
1545	Phosphorylation	IAKRSFSSQRPVDRQ HHHHHCCCCCCCCCC	28.35	30266825
1551	Methylation	SSQRPVDRQNRRGNN CCCCCCCCCCCCCCC	35.59	115489219
1563	Phosphorylation	GNNGPPKSGRNFSGP CCCCCCCCCCCCCCC	49.08	21406692
1565	Methylation	NGPPKSGRNFSGPRN CCCCCCCCCCCCCCC	48.38	115489227
1568	Phosphorylation	PKSGRNFSGPRNERR CCCCCCCCCCCCCCC	51.98	22167270
1576	Phosphorylation	GPRNERRSGPPSKSG CCCCCCCCCCCCCCC	62.97	23532336
1616	Phosphorylation	QEGVPNGTGQKNSKD CCCCCCCCCCCCCCC	42.98	24173317
1624	Phosphorylation	GQKNSKDSTGKKRED CCCCCCCCCCCCCCC	42.68	-
1625	Phosphorylation	QKNSKDSTGKKREDP CCCCCCCCCCCCCCC	64.25	-
1654	Phosphorylation	SQFDLNNYASVVIID HHCCCCCCCEEEEEC	10.12	-
1705	Phosphorylation	RRKKEEQVIQVWNKK HHHHHHHHHHHHHHC	3.60	16565220
1709	Phosphorylation	EEQVIQVWNKKNANE HHHHHHHHHHCCCCC	8.44	16565220
1711	Acetylation	QVIQVWNKKNANEKG HHHHHHHHCCCCCCC	31.52	26051181
1957	Phosphorylation	SSKQPPPSIRLPSAQ CCCCCCCCCCCCCCC	26.56	28555341
1959	Methylation	KQPPPSIRLPSAQTP CCCCCCCCCCCCCCC	44.90	115489195
1962	Phosphorylation	PPSIRLPSAQTPNGT CCCCCCCCCCCCCCC	37.29	30266825
1965	Phosphorylation	IRLPSAQTPNGTDYV CCCCCCCCCCCCCCC	20.59	30266825
1969	Phosphorylation	SAQTPNGTDYVASGK CCCCCCCCCCCCCCC	30.69	30266825
1971	Phosphorylation	QTPNGTDYVASGKSI CCCCCCCCCCCCCCC	9.58	29978859
1974	Phosphorylation	NGTDYVASGKSIQTP CCCCCCCCCCCCCCC	36.39	19691289
1976	Acetylation	TDYVASGKSIQTPQS CCCCCCCCCCCCCCC	41.72	26051181
1977	Phosphorylation	DYVASGKSIQTPQSH CCCCCCCCCCCCCCC	24.37	22496350
1980	Phosphorylation	ASGKSIQTPQSHGTL CCCCCCCCCCCCCEE	22.94	25159151
1983	Phosphorylation	KSIQTPQSHGTLTAE CCCCCCCCCCEEEHH	25.70	25159151
1986	Phosphorylation	QTPQSHGTLTAELWD CCCCCCCEEEHHHHC	18.60	30576142
1988	Phosphorylation	PQSHGTLTAELWDNK CCCCCEEEHHHHCCC	20.23	23186163
2006	Phosphorylation	PAVLNDISKKLGPIS HHHHHHHHHHHCCCC	26.97	26074081
2013	O-linked_Glycosylation	SKKLGPISPPQPPSV HHHHCCCCCCCCCCC	33.39	32574038
2013	Phosphorylation	SKKLGPISPPQPPSV HHHHCCCCCCCCCCC	33.39	25159151
2019	Phosphorylation	ISPPQPPSVSAWNKP CCCCCCCCCCCCCCC	35.07	23898821
2021	O-linked_Glycosylation	PPQPPSVSAWNKPLT CCCCCCCCCCCCCCC	31.72	32574038
2021	Phosphorylation	PPQPPSVSAWNKPLT CCCCCCCCCCCCCCC	31.72	28464451
2028	Phosphorylation	SAWNKPLTSFGSAPS CCCCCCCCCCCCCCC	30.45	27542207
2029	Phosphorylation	AWNKPLTSFGSAPSS CCCCCCCCCCCCCCC	34.98	25159151
2032	Phosphorylation	KPLTSFGSAPSSEGA CCCCCCCCCCCCHHH	34.69	25159151
2035	Phosphorylation	TSFGSAPSSEGAKNG CCCCCCCCCHHHCCC	40.51	25159151
2036	Phosphorylation	SFGSAPSSEGAKNGQ CCCCCCCCHHHCCCC	38.70	25159151
2061	O-linked_Glycosylation	IQFGAPASNGNENEV EECCCCCCCCCCCCE	44.18	32574038
2076	Phosphorylation	VPVLSEKSADKIPEP EEECCHHHCCCCCCH	37.33	28674419
2097	Acetylation	QPRAGPIKAQKLPDL CCCCCCCCCCCCCCC	48.15	25953088
2100	Acetylation	AGPIKAQKLPDLSPV CCCCCCCCCCCCCCC	67.84	25953088
2100	Malonylation	AGPIKAQKLPDLSPV CCCCCCCCCCCCCCC	67.84	26320211
2102 (in isoform 7)	Malonylation	-	47.75	26320211
2105	Phosphorylation	AQKLPDLSPVENKEH CCCCCCCCCCCCCCC	33.99	19664994
2110	Acetylation	DLSPVENKEHKPGPI CCCCCCCCCCCCCCC	47.92	7675695
2110	Malonylation	DLSPVENKEHKPGPI CCCCCCCCCCCCCCC	47.92	26320211
2112 (in isoform 7)	Malonylation	-	43.13	26320211
2122	Phosphorylation	GPIGKERSLKNRKVK CCCCCHHHCCCCCCC	44.80	-
2129	Acetylation	SLKNRKVKDAQQVEP HCCCCCCCCHHHCCC	50.83	26051181
2129	Methylation	SLKNRKVKDAQQVEP HCCCCCCCCHHHCCC	50.83	116254065
2141	Acetylation	VEPEGQEKPSPATVR CCCCCCCCCCCCCCC	42.80	26051181
2143	Phosphorylation	PEGQEKPSPATVRST CCCCCCCCCCCCCCC	37.93	29255136
2146	Phosphorylation	QEKPSPATVRSTDPV CCCCCCCCCCCCCCC	21.60	29255136
2149	Phosphorylation	PSPATVRSTDPVTTK CCCCCCCCCCCCCCH	32.59	26074081
2150	Phosphorylation	SPATVRSTDPVTTKE CCCCCCCCCCCCCHH	33.48	26074081
2154	Phosphorylation	VRSTDPVTTKETKAV CCCCCCCCCHHHHHH	37.22	26074081
2155	O-linked_Glycosylation	RSTDPVTTKETKAVS CCCCCCCCHHHHHHH	27.41	32574038
2155	Phosphorylation	RSTDPVTTKETKAVS CCCCCCCCHHHHHHH	27.41	26074081
2158	Phosphorylation	DPVTTKETKAVSEMS CCCCCHHHHHHHHHH	26.34	29978859
2162	Phosphorylation	TKETKAVSEMSTEIG CHHHHHHHHHHHCCC	32.23	22210691
2166	O-linked_Glycosylation	KAVSEMSTEIGTMIS HHHHHHHHCCCCEEE	30.25	32574038
2176	Phosphorylation	GTMISVSSAEYGTNA CCEEECCHHCCCCCC	23.98	-
2179	Phosphorylation	ISVSSAEYGTNAKES EECCHHCCCCCCCCC	29.03	22210691
2181	Phosphorylation	VSSAEYGTNAKESVT CCHHCCCCCCCCCCC	30.97	22210691
2186	O-linked_Glycosylation	YGTNAKESVTDYTTP CCCCCCCCCCCCCCC	29.61	32574038
2186	Phosphorylation	YGTNAKESVTDYTTP CCCCCCCCCCCCCCC	29.61	21945579
2188	O-linked_Glycosylation	TNAKESVTDYTTPSS CCCCCCCCCCCCCCH	32.35	32574038
2188	Phosphorylation	TNAKESVTDYTTPSS CCCCCCCCCCCCCCH	32.35	21945579
2190	Phosphorylation	AKESVTDYTTPSSSL CCCCCCCCCCCCHHC	11.80	21945579
2191	O-linked_Glycosylation	KESVTDYTTPSSSLP CCCCCCCCCCCHHCC	34.73	32574038
2191	Phosphorylation	KESVTDYTTPSSSLP CCCCCCCCCCCHHCC	34.73	21945579
2192	O-linked_Glycosylation	ESVTDYTTPSSSLPN CCCCCCCCCCHHCCC	18.23	32574038
2192	Phosphorylation	ESVTDYTTPSSSLPN CCCCCCCCCCHHCCC	18.23	21945579
2194	O-linked_Glycosylation	VTDYTTPSSSLPNTV CCCCCCCCHHCCCCC	30.39	32574038
2194	Phosphorylation	VTDYTTPSSSLPNTV CCCCCCCCHHCCCCC	30.39	21945579
2196	O-linked_Glycosylation	DYTTPSSSLPNTVAT CCCCCCHHCCCCCCC	52.78	32574038
2196	Phosphorylation	DYTTPSSSLPNTVAT CCCCCCHHCCCCCCC	52.78	25627689
2200	O-linked_Glycosylation	PSSSLPNTVATNNTK CCHHCCCCCCCCCCC	15.02	32574038
2203	O-linked_Glycosylation	SLPNTVATNNTKMED HCCCCCCCCCCCCCC	25.35	32574038
2211	O-linked_Glycosylation	NNTKMEDTLVNNVPL CCCCCCCCEECCCCC	21.21	32574038
2221	O-linked_Glycosylation	NNVPLPNTLPLPKRE CCCCCCCCCCCCCCH	28.01	32574038
2221	Phosphorylation	NNVPLPNTLPLPKRE CCCCCCCCCCCCCCH	28.01	28555341
2229	O-linked_Glycosylation	LPLPKRETIQQSSSL CCCCCCHHHCCCCCC	28.28	32574038
2233	O-linked_Glycosylation	KRETIQQSSSLTSVP CCHHHCCCCCCCCCC	12.91	32574038
2235	O-linked_Glycosylation	ETIQQSSSLTSVPPT HHHCCCCCCCCCCCC	40.70	32574038
2238	O-linked_Glycosylation	QQSSSLTSVPPTTFS CCCCCCCCCCCCEEE	37.61	32574038
2242	O-linked_Glycosylation	SLTSVPPTTFSLTFK CCCCCCCCEEEEEEE	34.11	32574038
2243	O-linked_Glycosylation	LTSVPPTTFSLTFKM CCCCCCCEEEEEEEH	19.59	32574038
2243	O-linked_Glycosylation	LTSVPPTTFSLTFKM CCCCCCCEEEEEEEH	19.59	20068230
2245	O-linked_Glycosylation	SVPPTTFSLTFKMES CCCCCEEEEEEEHHH	25.14	32574038
2247	O-linked_Glycosylation	PPTTFSLTFKMESAR CCCEEEEEEEHHHHH	21.73	32574038
2252	Phosphorylation	SLTFKMESARKAWEN EEEEEHHHHHHHHHC	29.85	17081983
2255	Acetylation	FKMESARKAWENSPN EEHHHHHHHHHCCCC	58.53	11792181
2260	O-linked_Glycosylation	ARKAWENSPNVREKG HHHHHHCCCCHHHCC	13.31	32574038
2260	Phosphorylation	ARKAWENSPNVREKG HHHHHHCCCCHHHCC	13.31	25159151
2268	O-linked_Glycosylation	PNVREKGSPVTSTAP CCHHHCCCCCCCCCC	27.54	32574038
2268	Phosphorylation	PNVREKGSPVTSTAP CCHHHCCCCCCCCCC	27.54	26074081
2271	O-linked_Glycosylation	REKGSPVTSTAPPIA HHCCCCCCCCCCCCC	24.60	32574038
2271	Phosphorylation	REKGSPVTSTAPPIA HHCCCCCCCCCCCCC	24.60	26074081
2272	O-linked_Glycosylation	EKGSPVTSTAPPIAT HCCCCCCCCCCCCCC	23.86	32574038
2272	Phosphorylation	EKGSPVTSTAPPIAT HCCCCCCCCCCCCCC	23.86	26074081
2273	O-linked_Glycosylation	KGSPVTSTAPPIATG CCCCCCCCCCCCCCC	33.54	32574038
2273	Phosphorylation	KGSPVTSTAPPIATG CCCCCCCCCCCCCCC	33.54	26074081
2279	O-linked_Glycosylation	STAPPIATGVSSSAS CCCCCCCCCCCCCCC	38.54	32574038
2282	O-linked_Glycosylation	PPIATGVSSSASGPS CCCCCCCCCCCCCCC	21.66	32574038
2284	O-linked_Glycosylation	IATGVSSSASGPSTA CCCCCCCCCCCCCCC	20.96	32574038
2286	O-linked_Glycosylation	TGVSSSASGPSTANY CCCCCCCCCCCCCCC	53.86	32574038
2289	O-linked_Glycosylation	SSSASGPSTANYNSF CCCCCCCCCCCCCCC	43.61	32574038
2321	Phosphorylation	SLSGAGTYTTSSLST CCCCCCEEECCCCCC	13.70	-
2330	O-linked_Glycosylation	TSSLSTKSTTTSDPP CCCCCCCCCCCCCCC	30.95	32574038
2331	O-linked_Glycosylation	SSLSTKSTTTSDPPN CCCCCCCCCCCCCCC	35.33	32574038
2332	O-linked_Glycosylation	SLSTKSTTTSDPPNI CCCCCCCCCCCCCCC	31.24	32574038
2349	O-linked_Glycosylation	VKPQQLQTSSLPSAS CCHHHCCCCCCCCCC	28.95	32574038
2354	O-linked_Glycosylation	LQTSSLPSASHFSQL CCCCCCCCCCHHHHH	47.93	32574038
2356	O-linked_Glycosylation	TSSLPSASHFSQLSC CCCCCCCCHHHHHCC	29.42	32574038
2380	O-linked_Glycosylation	QNPQVYVSQSAAAQI CCCCEEECHHHHHCC	10.75	32574038
2382	O-linked_Glycosylation	PQVYVSQSAAAQIPA CCEEECHHHHHCCCC	16.63	32574038
2400	O-linked_Glycosylation	DTSHLFNTQHARLAP CHHHHHCCCCCCCCC	17.88	32574038
2409	O-linked_Glycosylation	HARLAPPSLAQQQGF CCCCCCHHHHHHCCC	34.97	32574038
2421	O-linked_Glycosylation	QGFQPGLSQPTSVQQ CCCCCCCCCCCCCEE	39.77	32574038
2424	O-linked_Glycosylation	QPGLSQPTSVQQIPI CCCCCCCCCCEECCE	33.61	32574038
2425	O-linked_Glycosylation	PGLSQPTSVQQIPIP CCCCCCCCCEECCEE	25.31	32574038
2446	O-linked_Glycosylation	GQHQAQLSLGAGPAV CCCEEEEECCCCHHH	16.81	32574038
2454	O-linked_Glycosylation	LGAGPAVSQAQELFS CCCCHHHHHHHHHHH	23.16	32574038
2461	O-linked_Glycosylation	SQAQELFSSSLQPYR HHHHHHHHCCCCCHH	31.48	32574038
2462	O-linked_Glycosylation	QAQELFSSSLQPYRS HHHHHHHCCCCCHHC	27.94	32574038
2467 (in isoform 2)	Ubiquitination	-	15.22	21890473
2469	O-linked_Glycosylation	SSLQPYRSQPAFMQS CCCCCHHCCCHHHHC	34.37	32574038
2476	Phosphorylation	SQPAFMQSSLSQPSV CCCHHHHCCCCCCEE	22.81	28348404
2477	O-linked_Glycosylation	QPAFMQSSLSQPSVV CCHHHHCCCCCCEEE	18.36	32574038
2477	Phosphorylation	QPAFMQSSLSQPSVV CCHHHHCCCCCCEEE	18.36	28348404
2479	Phosphorylation	AFMQSSLSQPSVVLS HHHHCCCCCCEEEEE	41.83	27251275
2482	O-linked_Glycosylation	QSSLSQPSVVLSGTA HCCCCCCEEEEECEE	19.74	32574038
2482	Phosphorylation	QSSLSQPSVVLSGTA HCCCCCCEEEEECEE	19.74	28555341
2486	O-linked_Glycosylation	SQPSVVLSGTAIHNF CCCEEEEECEEHHCC	23.61	32574038
2488	O-linked_Glycosylation	PSVVLSGTAIHNFPT CEEEEECEEHHCCCC	21.04	32574038
2488	Phosphorylation	PSVVLSGTAIHNFPT CEEEEECEEHHCCCC	21.04	-
2506	Phosphorylation	QELAKAQSGLAFQQT HHHHHHHHCCCEEEC	40.40	-
2523	Phosphorylation	TQPIPILYEHQLGQA CCCCCEEEEEECCCC	16.46	-
2531	O-linked_Glycosylation	EHQLGQASGLGGSQL EEECCCCCCCCHHHH	27.02	32574038
2531	Phosphorylation	EHQLGQASGLGGSQL EEECCCCCCCCHHHH	27.02	-
2547	Methylation	DTHLLQARANLTQAS HHHHHHHHCCCHHHH	15.85	115389563
2572	Phosphorylation	GQTNFYNTAQSPSAL CCCCCCCCCCCCCHH	18.07	26074081
2575	Phosphorylation	NFYNTAQSPSALQQV CCCCCCCCCCHHCCC	20.54	26074081
2577	Phosphorylation	YNTAQSPSALQQVTV CCCCCCCCHHCCCEE	47.02	26074081
2583	O-linked_Glycosylation	PSALQQVTVPLPASQ CCHHCCCEEECCHHH	16.45	32574038
2589	O-linked_Glycosylation	VTVPLPASQLSLPNF CEEECCHHHCCCCCC	29.70	32574038
2592	O-linked_Glycosylation	PLPASQLSLPNFGST ECCHHHCCCCCCCCC	33.86	32574038
2633	O-linked_Glycosylation	LSRPAQVSQPFRGLI CCCCCCCCCCCCCCC	21.76	32574038
2637	Methylation	AQVSQPFRGLIPAGT CCCCCCCCCCCCCCC	45.77	12020489
2644	O-linked_Glycosylation	RGLIPAGTQHSMIAT CCCCCCCCCCCEEEE	25.80	32574038
2644	Phosphorylation	RGLIPAGTQHSMIAT CCCCCCCCCCCEEEE	25.80	22210691
2645 (in isoform 6)	Ubiquitination	-	26.24	21890473
2647	Phosphorylation	IPAGTQHSMIATTGK CCCCCCCCEEEECCC	11.32	28857561
2651	Phosphorylation	TQHSMIATTGKMSEM CCCCEEEECCCCCHH	25.75	22210691
2652	Phosphorylation	QHSMIATTGKMSEME CCCEEEECCCCCHHH	26.28	22210691
2654	Acetylation	SMIATTGKMSEMELK CEEEECCCCCHHHHH	36.84	25953088
2663 (in isoform 5)	Ubiquitination	-	8.38	21890473
2665	Phosphorylation	MELKAFGSGIDIKPG HHHHHHCCCCCCCCC	26.56	29255136
2670	Ubiquitination	FGSGIDIKPGTPPIA HCCCCCCCCCCCCCC	33.38	-
2672 (in isoform 7)	Ubiquitination	-	45.94	-
2673	O-linked_Glycosylation	GIDIKPGTPPIAGRS CCCCCCCCCCCCCCC	34.12	32574038
2673	Phosphorylation	GIDIKPGTPPIAGRS CCCCCCCCCCCCCCC	34.12	29255136
2673 (in isoform 3)	Phosphorylation	-	34.12	29116813
2679	Methylation	GTPPIAGRSTTPTSS CCCCCCCCCCCCCCC	23.08	115489155
2680	O-linked_Glycosylation	TPPIAGRSTTPTSSP CCCCCCCCCCCCCCC	35.40	32574038
2680	Phosphorylation	TPPIAGRSTTPTSSP CCCCCCCCCCCCCCC	35.40	30266825
2681	Phosphorylation	PPIAGRSTTPTSSPF CCCCCCCCCCCCCCC	35.12	30266825
2682	Phosphorylation	PIAGRSTTPTSSPFR CCCCCCCCCCCCCCC	26.30	19664994
2684	O-linked_Glycosylation	AGRSTTPTSSPFRAT CCCCCCCCCCCCCCC	39.48	32574038
2684	Phosphorylation	AGRSTTPTSSPFRAT CCCCCCCCCCCCCCC	39.48	22167270
2685	O-linked_Glycosylation	GRSTTPTSSPFRATS CCCCCCCCCCCCCCC	36.90	32574038
2685	Phosphorylation	GRSTTPTSSPFRATS CCCCCCCCCCCCCCC	36.90	22167270
2686	O-linked_Glycosylation	RSTTPTSSPFRATST CCCCCCCCCCCCCCC	30.45	32574038
2686	Phosphorylation	RSTTPTSSPFRATST CCCCCCCCCCCCCCC	30.45	22167270
2689	Methylation	TPTSSPFRATSTSPN CCCCCCCCCCCCCCC	40.10	54554639
2691	Phosphorylation	TSSPFRATSTSPNSQ CCCCCCCCCCCCCCC	28.42	22167270
2692	O-linked_Glycosylation	SSPFRATSTSPNSQS CCCCCCCCCCCCCCH	26.38	32574038
2692	Phosphorylation	SSPFRATSTSPNSQS CCCCCCCCCCCCCCH	26.38	22167270
2693	O-linked_Glycosylation	SPFRATSTSPNSQSS CCCCCCCCCCCCCHH	43.80	32574038
2693	O-linked_Glycosylation	SPFRATSTSPNSQSS CCCCCCCCCCCCCHH	43.80	20068230
2693	Phosphorylation	SPFRATSTSPNSQSS CCCCCCCCCCCCCHH	43.80	22167270
2694	O-linked_Glycosylation	PFRATSTSPNSQSSK CCCCCCCCCCCCHHH	23.11	32574038
2694	Phosphorylation	PFRATSTSPNSQSSK CCCCCCCCCCCCHHH	23.11	22167270
2697	Phosphorylation	ATSTSPNSQSSKMNS CCCCCCCCCHHHHCC	34.52	22167270
2699	Phosphorylation	STSPNSQSSKMNSIV CCCCCCCHHHHCCEE	31.57	22167270
2700	Phosphorylation	TSPNSQSSKMNSIVY CCCCCCHHHHCCEEE	28.43	28450419
2701	Acetylation	SPNSQSSKMNSIVYQ CCCCCHHHHCCEEEH	47.55	25953088
2703 (in isoform 7)	Ubiquitination	-	32.11	-
2704	Phosphorylation	SQSSKMNSIVYQKQF CCHHHHCCEEEHHHH	15.21	21945579
2707	Phosphorylation	SKMNSIVYQKQFQSA HHHCCEEEHHHHCCC	14.34	21945579
2709	Ubiquitination	MNSIVYQKQFQSAPA HCCEEEHHHHCCCCC	35.08	2189047
2709 (in isoform 4)	Ubiquitination	-	35.08	21890473
2710 (in isoform 1)	Ubiquitination	-	26.53	21890473
2711 (in isoform 7)	Ubiquitination	-	8.80	21890473
2712 (in isoform 7)	Ubiquitination	-	35.87	21890473
2713	Phosphorylation	VYQKQFQSAPATVRM EEHHHHCCCCCEEEE	37.19	23312004
2717	O-linked_Glycosylation	QFQSAPATVRMTQPF HHCCCCCEEEECCCC	13.95	32574038
2719	Dimethylation	QSAPATVRMTQPFPT CCCCCEEEECCCCCC	20.34	-
2719	Methylation	QSAPATVRMTQPFPT CCCCCEEEECCCCCC	20.34	54554631
2721	O-linked_Glycosylation	APATVRMTQPFPTQF CCCEEEECCCCCCCC	23.64	32574038
2792	Phosphorylation	RGPCGSLSGVRGNQA CCCCCCCCCCCCHHH	36.62	24719451
2795	Methylation	CGSLSGVRGNQAQAA CCCCCCCCCHHHHHH	41.70	30986171
2814	Methylation	QDMKAKQRAEVLQST HHHHHHHHHHHHHHH	31.82	12229633
2817	Phosphorylation	KAKQRAEVLQSTQRF HHHHHHHHHHHHHHH	6.02	24719451
2823	Asymmetric dimethylarginine	EVLQSTQRFFSEQQQ HHHHHHHHHHCHHHH	34.37	-
2823	Methylation	EVLQSTQRFFSEQQQ HHHHHHHHHHCHHHH	34.37	18967727
2826	Phosphorylation	QSTQRFFSEQQQSKQ HHHHHHHCHHHHHHC	31.61	28555341
2841	Acetylation	IGGGKAQKVDSDSSK CCCCCCCCCCCCCCC	53.52	26051181
2846	Phosphorylation	AQKVDSDSSKPPETL CCCCCCCCCCCCCCC	44.18	28258704
2847	Phosphorylation	QKVDSDSSKPPETLT CCCCCCCCCCCCCCC	54.92	28258704
2848	Acetylation	KVDSDSSKPPETLTD CCCCCCCCCCCCCCC	69.42	26051181
2873	Phosphorylation	EKPPPAPSIATKPVR CCCCCCCCCCCCCCC	27.28	28555341
2877	Acetylation	PAPSIATKPVRTGPI CCCCCCCCCCCCCCC	32.28	23954790
2885	Acetylation	PVRTGPIKPQAIKTE CCCCCCCCCCCCCCC	33.92	26051181
2890	Acetylation	PIKPQAIKTEETKS- CCCCCCCCCCCCCC-	53.55	26051181
2894	Phosphorylation	QAIKTEETKS----- CCCCCCCCCC-----	30.29	21712546
2896	Phosphorylation	IKTEETKS------- CCCCCCCC-------	53.53	24719451

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
661	S	Phosphorylation	Kinase	CHEK1	O14757	GPS
1013	S	Phosphorylation	Kinase	AURKB	Q96GD4	GPS

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of PRC2C_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
2709	Ubiquitination	2717 (8)	T ⇒ A	rs2421847	Alzheimer's disease (cognitive decline)	23535033
2710	Ubiquitination	2717 (7)	T ⇒ A	rs2421847	Alzheimer's disease (cognitive decline)	23535033
2712	Ubiquitination	2719 (7)	T ⇒ A	rs2421847	Alzheimer's disease (cognitive decline)	23535033

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of PRC2C_HUMAN !!

Drug and Disease Associations

Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of PRC2C_HUMAN

Related Literatures of Post-Translational Modification

Acetylation
Reference	PubMed
"Lysine acetylation targets protein complexes and co-regulates majorcellular functions."; Choudhary C., Kumar C., Gnad F., Nielsen M.L., Rehman M., Walther T.,Olsen J.V., Mann M.; Science 325:834-840(2009). Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-27; LYS-47 AND LYS-392, ANDMASS SPECTROMETRY.	19608861 [Abstract]
Phosphorylation
Reference	PubMed
"Quantitative phosphoproteomic analysis of T cell receptor signalingreveals system-wide modulation of protein-protein interactions."; Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K.,Rodionov V., Han D.K.; Sci. Signal. 2:RA46-RA46(2009). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-187; SER-878; SER-1249;SER-2105; THR-2673 AND THR-2682, AND MASS SPECTROMETRY.	19690332 [Abstract]
"Lys-N and trypsin cover complementary parts of the phosphoproteome ina refined SCX-based approach."; Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J.,Mohammed S.; Anal. Chem. 81:4493-4501(2009). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-187; SER-189; SER-878;SER-2013 AND SER-2105, AND MASS SPECTROMETRY.	19413330 [Abstract]
"A quantitative atlas of mitotic phosphorylation."; Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E.,Elledge S.J., Gygi S.P.; Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-187; SER-191; SER-779;SER-878; SER-2013; SER-2105; SER-2143 AND THR-2673, AND MASSSPECTROMETRY.	18669648 [Abstract]
"Kinase-selective enrichment enables quantitative phosphoproteomics ofthe kinome across the cell cycle."; Daub H., Olsen J.V., Bairlein M., Gnad F., Oppermann F.S., Korner R.,Greff Z., Keri G., Stemmann O., Mann M.; Mol. Cell 31:438-448(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-2105, AND MASSSPECTROMETRY.	18691976 [Abstract]
"Improved titanium dioxide enrichment of phosphopeptides from HeLacells and high confident phosphopeptide identification by cross-validation of MS/MS and MS/MS/MS spectra."; Yu L.-R., Zhu Z., Chan K.C., Issaq H.J., Dimitrov D.S., Veenstra T.D.; J. Proteome Res. 6:4150-4162(2007). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-2143 AND THR-2673, ANDMASS SPECTROMETRY.	17924679 [Abstract]
"A probability-based approach for high-throughput proteinphosphorylation analysis and site localization."; Beausoleil S.A., Villen J., Gerber S.A., Rush J., Gygi S.P.; Nat. Biotechnol. 24:1285-1292(2006). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-2105, AND MASSSPECTROMETRY.	16964243 [Abstract]
"Global, in vivo, and site-specific phosphorylation dynamics insignaling networks."; Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P.,Mann M.; Cell 127:635-648(2006). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-500; SER-779; SER-878;SER-1242; THR-1244; SER-1246; SER-1249; SER-2105 AND THR-2673, ANDMASS SPECTROMETRY.	17081983 [Abstract]