TAD2B_DROME - dbPTM
TAD2B_DROME - PTM Information in dbPTM
Basic Information of Protein
UniProt ID TAD2B_DROME
UniProt AC Q8I8V0
Protein Name Transcriptional adapter 2B
Gene Name Ada2b {ECO:0000312|FlyBase:FBgn0037555}
Organism Drosophila melanogaster (Fruit fly).
Sequence Length 555
Subcellular Localization Nucleus .
Protein Description Required for the function of some acidic activation domains, which activate transcription from a distant site. Binds double-stranded DNA. Binds dinucleosomes, probably at the linker region between neighboring nucleosomes. Plays a role in chromatin remodeling..
Protein Sequence MTTIADLFTKYNCTNCQDDIQGIRVHCAECENFDLCLQCFAAGAEIGAHQNNHSYQFMDTGTSILSVFRGKGAWTAREEIRLLDAIEQYGFGNWEDISKHIETKSAEDAKEEYVNKFVNGTIGRATWTPAQSQRPRLIDHTGDDDAGPLGTNALSTLPPLEINSDEAMQLGYMPNRDSFEREYDPTAEQLISNISLSSEDTEVDVMLKLAHVDIYTRRLRERARRKRMVRDYQLVSNFFRNRNYAQQQGLTKEQREFRDRFRVYAQFYTCNEYERLLGSLEREKELRIRQSELYRYRYNGLTKIAECTHFEQHAATATHRSTGPYGHGKTDHTHTSNGSHRPPSSSLHSPQPNLRKVEMSSGGEASSNSIAPRNTLHIADPTCSGALLPSKNYLDSCRGSSAATMLQTTGMVMGVTVDSGATTGVTSTATTMANLPTNSAKGSQQHLQPLQQHPQLLQSGNQHKMQNEAAGGGSDQVPSMSLKLRTQLEELKHLPQPPGSELLSHNELDLCKKHNITPTTYLSVKTVCLSGAPSLGSPMETSLRKFFIKCGWLSH
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster

Oops, there are no PTM records of TAD2B_DROME !!

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of TAD2B_DROME !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of TAD2B_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of TAD2B_DROME !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
TAF5_DROMETaf5physical
12697829
TAF9_DROMEe(y)1physical
12697829
TAF10_DROMETaf10physical
12697829
TAD2A_DROMEAda2aphysical
12697829
VND_DROMEvndphysical
21764853
HMOC_DROMEocphysical
21764853
MYB_DROMEMybphysical
21764853
TAF9_DROMEe(y)1physical
20008933
TAF9_DROMEe(y)1physical
21764853
TAF9_DROMEe(y)1physical
12482983
CREBB_DROMECrebBphysical
21764853
TAFAB_DROMETaf10bphysical
20008933
TAFAB_DROMETaf10bphysical
21764853
TAF10_DROMETaf10physical
12482983
CFA20_DROMECG5343physical
21764853
STC_DROMEstcphysical
21764853
E2F2_DROMEE2f2physical
21764853
TRA1_DROMENipped-Aphysical
20008933
TRA1_DROMENipped-Aphysical
21764853
TRA1_DROMENipped-Aphysical
12697829
MEF2_DROMEMef2physical
21764853
JRA_DROMEJraphysical
21764853
HR3_DROMEHr46physical
21764853
TFDP_DROMEDpphysical
21764853
CHN_DROMEchnphysical
21764853
HSF_DROMEHsfphysical
21764853
TBP_DROMETbpphysical
12482983
FOSLD_DROMEkayphysical
21764853
FOSLA_DROMEkayphysical
21764853
KEN_DROMEkenphysical
21764853
CF1A_DROMEvvlphysical
21764853
TAF4_DROMETaf4physical
12482983
NOT_DROMEnotphysical
20008933
NOT_DROMEnotphysical
21764853
SGF11_DROMESgf11physical
20008933
SGF11_DROMESgf11physical
21764853
FTZF1_DROMEftz-f1physical
21764853
MAX_DROMEMaxphysical
21764853
DEAF1_DROMEDeaf1physical
21764853
HR78_DROMEHr78physical
21764853
TAD2B_DROMEAda2bphysical
23336284
ARNT_DROMEtgophysical
21764853
TAF12_DROMETaf12physical
20008933
TAF12_DROMETaf12physical
21764853
FRU_DROMEfruphysical
21764853
STAT_DROMEStat92Ephysical
21764853
ELG_DROMEEts97Dphysical
21764853
FKH_DROMEfkhphysical
21764853
PITX_DROMEPtx1physical
21764853
CI_DROMEciphysical
21764853
HCF_DROMEHcfphysical
21764853
ZFH2_DROMEzfh2physical
21764853
PHO_DROMEphophysical
21764853
BAB2_DROMEbab2physical
21764853
BRC1_DROMEbrphysical
21764853
BRC4_DROMEbrphysical
21764853
CUT_DROMEctphysical
21764853
PNR_DROMEpnrphysical
21764853
ENY2_DROMEe(y)2physical
20008933
ENY2_DROMEe(y)2physical
21764853
SF3B5_DROMECG11985physical
27185460

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of TAD2B_DROME

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Related Literatures of Post-Translational Modification

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