| UniProt ID | CHN_DROME | |
|---|---|---|
| UniProt AC | Q7YU81 | |
| Protein Name | Protein charlatan | |
| Gene Name | chn | |
| Organism | Drosophila melanogaster (Fruit fly). | |
| Sequence Length | 1214 | |
| Subcellular Localization | Nucleus . | |
| Protein Description | Probable transcription factor involved in the development of the adult pattern of macrochaetae. Required for accumulation of achaete (ac) and scute (sc) in proneural clusters. Probably acts by binding to the proneural cluster-specific enhancers of the ac/sc complex and increasing enhancer efficiency, thereby acting as a stimulator of ac/sc expression in proneural clusters. Also required for correct development of the embryonic/larval peripheral nervous system (PNS).. | |
| Protein Sequence | MATLIPVNGGHPAASGQSSNVEATYEDMFKEITRKLYGEETGNGLHTLGTPVAQVATSGPTAVPEGEQRSFTNLQQLDRSAAPSIEYESSAAGASGNNVATTQANVIQQQQQQQQQAESGNSVVVTASSGATVVPAPSVAAVGGFKSEDHLSTAFGLAALMQNGFAAGQAGLLKAGEQQQRWAQDGSGLVAAAAAEPQLVQWTSGGKLQSYAHVNQQQQQQQQPHQSTPKSKKHRQEHAAELIYASPSTSANAAQNLAQSTPTSAPSNSSGGSTSSSGGGGGRKKAAQAAAAAAAANGVHIQKRYACTHCPYSTDRRDLYTRHENIHKDEKPFQCYACLKQFNRADHVKKHFLRMHRELQYDINKTRRHVSAGSGSSGSGSSGSGSHHSGGRGNVTINSAGVNIDNAFLEAQRHPTSSSMSIVETIEAVASATDMPLAQLKQEKMDDGAGVVLPLHVGVMQQPVASSSSGSSGSHGGNGNGGSGSGLLKPKREKRFTCCYCPWSGADKWGLKRHLNTHTKPFVCLLCDYKAARSERLATHVLKVHNKRACSKCSYLADTQEEYQAHMSDVHGNVGNANGGGGAVTIYTTTTNEGVAGGGGGGGGGISGNISGGGPLQEIIVNPSSMVGWRLSANGSLIPPHDLLTGGLPNAATQKRGSERLFQYLEAEGSDPEDYARLLKMDAISRNTASVAQDFHKAGGVHELKIPANHQLLFNNKLPSQWTTREAAALLYSLSNMGGGSASSVSGSQRQKFGMRARQHSTGEDDENTPSSASSSSFSGDEFNMSATSPLKLSRHAIKLEKMDEMDAKDMGPTKAMMATAFLEAANYEQTAIELLASKRKIKVENDNDEDQENQQHQPHQQHHSQQQQQQRLQLIKSSPAYKLNNNNNNNSNNNNYYKDKTSHRNAVHHHRQDDKENNKTKSPGTAAVSVAAAAATSPPSISGPSNQTPFLTQMEYQNLNRIGTQFQNYVKDIINKYYAAETPLMLAAAAAALPTATTTGQQQQPELDIENLSPSKRRRLLSETEEYIEYLRNKEDITLTIAPKVQPPAPVTSLLKRQLDLSTPRRSPKKAAPAHSNSASNASRKSLNQLATLLPLLADAASQQEYLAAPLDFSKKSSSRKQAQPKKIRLTPEAVVTLLRDKYLNRMVRQRLGCLKCNQLRKNSSISFNYHTLGSLALHKYWRHGRLGSSSTRREKLQAALQKRISRGQADKC | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 1068 | Phosphorylation | DLSTPRRSPKKAAPA CCCCCCCCCCCCCCC | 42.21 | 22668510 | |
| 1077 | Phosphorylation | KKAAPAHSNSASNAS CCCCCCCCCCCCHHC | 34.29 | 22668510 | |
| 1084 | Phosphorylation | SNSASNASRKSLNQL CCCCCHHCHHHHHHH | 44.48 | 22668510 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of CHN_DROME !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of CHN_DROME !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of CHN_DROME !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| HSP83_DROME | Hsp83 | physical | 14605208 | |
| SALA_DROME | sala | physical | 14605208 | |
| RS2_DROME | RpS2 | physical | 14605208 | |
| AKIRN_DROME | akirin | physical | 14605208 | |
| ZC3HF_DROME | CG8635 | physical | 14605208 | |
| EBI_DROME | ebi | genetic | 16763555 | |
| RCOR_DROME | CoRest | physical | 16763555 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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