TAD2A_DROME - dbPTM
TAD2A_DROME - PTM Information in dbPTM
Basic Information of Protein
UniProt ID TAD2A_DROME
UniProt AC Q7KSD8
Protein Name Transcriptional adapter 2A
Gene Name Ada2a {ECO:0000303|PubMed:12482983, ECO:0000312|FlyBase:FBgn0263738}
Organism Drosophila melanogaster (Fruit fly).
Sequence Length 562
Subcellular Localization Nucleus .
Protein Description GCN5-independent Rpb4 complexes are highly enriched in decondensed chromosome puffs so may play a role in RNA polymerase II-dependent transcription..
Protein Sequence MSFMNPVDMVDEDAADLQFPKVALLHIFTTLNCLFAVEPLGPQVKRFIHAHQNEHTRNSMVLYNPHTLHRYLEEMEEKTRDQNSSVPSATKDANRCATCRCSLTEPYIKCSECLDTLLCLQCFSRGKEAFSHRNNHAYIIVRDNIQVFADEPHWTARDERILLKTLRTHGYGNWEAVSQALDQRHEPAEVRRHYHDCYFGGIFERLLNLKHARDSYVPERMPYVFKMRSLDPPRHDDIASMQFRLSAGYRCARGDFDTPYDTSAESLLSIMVDHRGRDDDNEASESEFEREVTEELQLGLVRAYNNRLRERQRRYKIMRQHGLIMPNRTVSWISKYVHAFGSDASCMRFLGFMQICPDPIKFDMLLESLRYYRELHSQLHKLYDLREHGVRTLSGAKLYARLSKERQQAQRDYSRLKQTDAFDWQQLVQHYESNRSGDPGPLAINSKLYVMNTRRKASPIEIGGGKHFTHCLTPTEYNFSLIPDLPGYSKLDDGERKLCSVARLVPQSYLDYKNQLVTEQAKLGYLRLADARRLIKIDVNKTRQIYDFLLEHGHISRPPSYG
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster

Oops, there are no PTM records of TAD2A_DROME !!

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of TAD2A_DROME !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of TAD2A_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of TAD2A_DROME !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
MOC2B_DROMEMocs2physical
20813260
TAD2A_DROMEAda2aphysical
20813260
HCF_DROMEHcfphysical
20813260
NC2B_DROMENC2betaphysical
20813260
WDS_DROMEwdsphysical
20813260
MOC2B_DROMEMocs2physical
22345504
NC2B_DROMENC2betaphysical
22345504
HCF_DROMEHcfphysical
22345504
WDS_DROMEwdsphysical
22345504
TAF9_DROMEe(y)1physical
12482983
NC2B_DROMENC2betaphysical
18327268
TBP_DROMETbpphysical
12482983
TAD2B_DROMEAda2bphysical
12482983
MOC2B_DROMEMocs2physical
18327268
HCF_DROMEHcfphysical
16428443
HCF_DROMEHcfphysical
18327268
WDS_DROMEwdsphysical
18327268

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of TAD2A_DROME

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Related Literatures of Post-Translational Modification

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