dbPTM

BRC1_DROME - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	BRC1_DROME
UniProt AC	Q01295
Protein Name	Broad-complex core protein isoforms 1/2/3/4/5
Gene Name	br
Organism	Drosophila melanogaster (Fruit fly).
Sequence Length	727
Subcellular Localization	Nucleus.
Protein Description	Broad-complex proteins are required for puffing and transcription of salivary gland late genes during metamorphosis..
Protein Sequence	MDDTQHFCLRWNNYQSSITSAFENLRDDEAFVDVTLACEGRSIKAHRVVLSACSPYFRELLKSTPCKHPVILLQDVNFMDLHALVEFIYHGEVNVHQKSLQSFLKTAEVLRVSGLTQQQAEDTHSHLAQIQNLANSGGRTPLNTHTQSLPHPHHGSLHDDGGSSTLFSRQGAGSPPPTAVPSLPSHINNQLLKRMAMMHRSSAAAAAEETSHAFKRLRGSDNSLPLSGAVGSGSNNNSPDLPPLHARSASPQQTPADFSTIKHHNNNNTPPLKEEKRNGPTGNGNSGNGNGNGNGASNGNGISISDKLGSLTPSPLARAGADDVKSEPMDMVCSNNNANANDEHSNDSTGEHDANRSSSGDGGKGSLSSGNDEEIGDGLASHHAAPQFIMSPAENKMFHAAAFNFPNIDPSALLGLNTQLQQSGDLAVSPQGKLTTNATTTTTTINNSITNNNNNNNNNNYDYSLPTKNSNSQKTPSPTTTTLTTPTTTTPTRPTAITSASGICGLNLSTFAANGSSSGGSNGGLSMTALLPQQQQQQQQQHQMSQQQQQQQQQQQQQGNSSSGQQQQPNGILACSTPKANTPTTTQQQMYAAVMAAAASASASTSGSANSSLNNSNSTLNTSGGLNNSASGGDDFRCNPCNKNLSSLTRLKRHIQNVHMRPTKEPVCNICKRVYSSLNSLRNHKSIYHRNLKQPKQEPGVGATQAAANSFYHQQHQQQQLNHHSSS

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
Oops, there are no PTM records of BRC1_DROME !!

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of BRC1_DROME !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of BRC1_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of BRC1_DROME !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
PP2A_DROME	mts	physical	14605208
LIMK1_DROME	LIMK1	genetic	14972681
RHO1_DROME	Rho1	genetic	14668390
RHO1_DROME	Rho1	genetic	14972681
SRF_DROME	bs	genetic	14668390
MYSN_DROME	zip	genetic	14972681
TPM1_DROME	Tm1	genetic	14668390
TPM4_DROME	Tm1	genetic	14668390
STUB_DROME	Sb	genetic	14668390

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of BRC1_DROME

Related Literatures of Post-Translational Modification