| UniProt ID | BRC4_DROME | |
|---|---|---|
| UniProt AC | Q24206 | |
| Protein Name | Broad-complex core protein isoform 6 | |
| Gene Name | br | |
| Organism | Drosophila melanogaster (Fruit fly). | |
| Sequence Length | 880 | |
| Subcellular Localization | Nucleus. | |
| Protein Description | Broad-complex proteins are required for puffing and transcription of salivary gland late genes during metamorphosis.. | |
| Protein Sequence | MDDTQHFCLRWNNYQSSITSAFENLRDDEAFVDVTLACEGRSIKAHRVVLSACSPYFRELLKSTPCKHPVILLQDVNFMDLHALVEFIYHGEVNVHQKSLQSFLKTAEVLRVSGLTQQQAEDTHSHLAQIQNLANSGGRTPLNTHTQSLPHPHHGSLHDDGGSSTLFSRQGAGSPPPTAVPSLPSHINNQLLKRMAMMHRSSAAAAAEETSHAFKRLRGSDNSLPLSGAVGSGSNNNSPDLPPLHARSASPQQTPADFSTIKHHNNNNTPPLKEEKRNGPTGNGNSGNGNGNGNGASNGNGISISDKLGSLTPSPLARAGADDVKSEPMDMVCSNNNANANDEHSNDSTGEHDANRSSSGDGGKGSLSSGNDEEIGDGLASHHAAPQFIMSPAENKMFHAAAFNFPNIDPSALLGLNTQLQQSGDLAVSPQGGSTGSLLSGVIVPGGSGGTPSNSSSNNNNNNSNNQQQKVEQQSSPHQLLQQQHHSTPHTNSPQLKQEQPKSGGGSCKSSDLHIAAGSERSLSRSSQGMPDAGGHSATPSPTAAYHKRERERERERERERERERERSLDHERDLERPGGTGSPPPPPPSHHSHFGQHPLSLLPSHHQLHATHHELSAAAAHHAHAHAHAAHAHALARAGSPMEHHHLLHHRRASLSPSGAVSSASGAGGRGGGAGGPGGPGGSLLSSVRAQDVAQANRLLLPLPLNACHRCDVCGKLLSTKLTLKRHKEQQHLQPLNNAVCNLCHKVFRTLNSLNNHKSIYHRRQKNHHSYFHHGAGVSQAGSPGSRLHQSLSSLSAAAAAANNSVNVGGGSVGGAGGNAVAAAAAAAAAAAELLLSPIVGAAAVAGGTASSTLQLAAAHQQQQQQSSPGIVKPCMDFL | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 174 | Phosphorylation | FSRQGAGSPPPTAVP CCCCCCCCCCCCCCC | 33.43 | 19429919 | |
| 248 | Phosphorylation | LPPLHARSASPQQTP CCCCCCCCCCCCCCC | 33.60 | 19429919 | |
| 250 | Phosphorylation | PLHARSASPQQTPAD CCCCCCCCCCCCCCC | 25.20 | 19429919 | |
| 269 | Phosphorylation | KHHNNNNTPPLKEEK CCCCCCCCCCCCHHH | 28.54 | 19429919 | |
| 312 | Phosphorylation | SDKLGSLTPSPLARA HHCCCCCCCCHHHHC | 24.34 | 27626673 | |
| 314 | Phosphorylation | KLGSLTPSPLARAGA CCCCCCCCHHHHCCC | 27.58 | 27626673 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of BRC4_DROME !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of BRC4_DROME !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of BRC4_DROME !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| PP2A_DROME | mts | physical | 14605208 | |
| LIMK1_DROME | LIMK1 | genetic | 14972681 | |
| RHO1_DROME | Rho1 | genetic | 14668390 | |
| RHO1_DROME | Rho1 | genetic | 14972681 | |
| SRF_DROME | bs | genetic | 14668390 | |
| MYSN_DROME | zip | genetic | 14972681 | |
| TPM1_DROME | Tm1 | genetic | 14668390 | |
| TPM4_DROME | Tm1 | genetic | 14668390 | |
| STUB_DROME | Sb | genetic | 14668390 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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