ELG_DROME - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ELG_DROME
• UniProt AC: Q04688
• Protein Name: DNA-binding protein Ets97D
• Gene Name: Ets97D
• Organism: Drosophila melanogaster (Fruit fly).
• Sequence Length: 464
• Subcellular Localization: Nucleus.
• Protein Description: May have a role in germline development..
• Protein Sequence: MNSSNDLSDELIRRLSVGGALEEVIASEMFEDSIDVETEAEPDDIIIVHMDIREPLSMLKSLVEQKIGVCLNYYTFWLQDAQELESHKNLVDQCVKGEGLVQINVQIQTIRKRINIADVLKPTEAALAALAEEVVGQLSPPETASQKSSSSESPIKTPLKRMHKEDSEEESVEGKDVKPVLNWVLDSKFKREQIRLKIPEAANEWTHAHVTYWLEWAVKQFELVGINMSDWQMNGQELCAMTHEEFNQKLPRDPGNIFWTHLQLLKECNFVSVVHKRAEEQRKPKQPRIMSANSISTNSGGSLSLEQRIMRKSYQSVKSSDSVESTTSSMNPSNYTTIGSGNNGQVQLWQFLLEILTDCEHTDVIEWVGTEGEFKLTDPDRVARLWGEKKNKPAMNYEKLSRALRYYYDGDMISKVSGKRFAYKFDCDLKLLIGYDANELSTLVSEGKTAPERVAATETITEDT

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
151	Phosphorylation	ASQKSSSSESPIKTP CCCCCCCCCCCCCCC	44.00	22817900
153	Phosphorylation	QKSSSSESPIKTPLK CCCCCCCCCCCCCCH	33.60	22817900
157	Phosphorylation	SSESPIKTPLKRMHK CCCCCCCCCCHHHCC	34.27	25749252
167	Phosphorylation	KRMHKEDSEEESVEG HHHCCCCCCCCCCCC	48.26	19429919
171	Phosphorylation	KEDSEEESVEGKDVK CCCCCCCCCCCCCHH	28.84	22817900

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ELG_DROME !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ELG_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ELG_DROME !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
CAPU_DROME	capu	genetic	7566961

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Phosphorylation

"Phosphoproteome analysis of Drosophila melanogaster embryos.";
Zhai B., Villen J., Beausoleil S.A., Mintseris J., Gygi S.P.;
J. Proteome Res. 7:1675-1682(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-153; THR-157; SER-167AND SER-171, AND MASS SPECTROMETRY.
PubMed: 18327897