| UniProt ID | TAF4_DROME | |
|---|---|---|
| UniProt AC | P47825 | |
| Protein Name | Transcription initiation factor TFIID subunit 4 | |
| Gene Name | Taf4 | |
| Organism | Drosophila melanogaster (Fruit fly). | |
| Sequence Length | 921 | |
| Subcellular Localization | Nucleus. | |
| Protein Description | TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. May function as a coactivator by serving as a site of protein-protein contact between activators like Sp1 (or btd) and TFIID complex.. | |
| Protein Sequence | MNTSQTAAGNRITFTSQPLPNGTISIAGNPGAVISTAQLPNTTTIKTIQAGIGGQHQGLQQVHHVQQQQQSQQQQQQQQQTQSAGQPLLNSMLPAGVVVGMRQQAPSQQQQKNVPTNPLSRVVINSHMAGVRPQSPSITLSTLNTGQTPALLVKTDNGFQLLRVGTTTGPPTVTQTITNTSNNSNTTSTTNHPTTTQIRLQTVPAAASMTNTTATSNIIVNSVASSGYANSSQPPHLTQLNAQAPQLPQITQIQTIPAQQSQQQQVNNVSSAGGTATAVSSTTAATTTQQGNTKEKCRKFLANLIELSTREPKPVEKNVRTLIQELVNANVEPEEFCDRLERLLNASPQPCLIGFLKKSLPLLRQALYTKELVIEGIKPPPQHVLGLAGLSQQLPKIQAQIRPIGPSQTTTIGQTQVRMITPNALGTPRPTIGHTTISKQPPNIRLPTAPRLVNTGGIRTQIPSLQVPGQANIVQIRGPQHAQLQRTGSVQIRATTRPPNSVPTANKLTAVKVGQTQIKAITPSLHPPSLAAISGGPPPTPTLSVLSTLNSASTTTLPIPSLPTVHLPPEALRAREQMQNSLNHNSNHFDAKLVEIKAPSLHPPHMERINASLTPIGAKTMARPPPAINKAIGKKKRDAMEMDAKLNTSSGGAASAANSFFQQSSMSSMYGDDDINDVAAMGGVNLAEESQRILGCTENIGTQIRSCKDEVFLNLPSLQARIRAITSEAGLDEPSQDVAVLISHACQERLKNIVEKLAVIAEHRIDVIKLDPRYEPAKDVRGQIKFLEELDKAEQKRHEELEREMLLRAAKSRSRVEDPEQAKMKARAKEMQRAEMEELRQRDANLTALQAIGPRKKLKLDGETVSSGAGSSGGGVLSSSGSAPTTLRPRIKRVNLRDMLFYMEQEREFCRSSMLFKTYLK | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 347 | Phosphorylation | LERLLNASPQPCLIG HHHHHHCCCCCCHHH | 24.01 | 21082442 | |
| 507 | Acetylation | NSVPTANKLTAVKVG CCCCCCCCCEEEEEC | 44.76 | 21791702 | |
| 630 | Acetylation | RPPPAINKAIGKKKR CCCCHHHHHHCCCHH | 34.96 | 21791702 | |
| 634 | Acetylation | AINKAIGKKKRDAME HHHHHHCCCHHHHHH | 49.35 | 21791702 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of TAF4_DROME !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of TAF4_DROME !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of TAF4_DROME !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| GAGA_DROME | Trl | physical | 14605208 | |
| TAF1_DROME | Taf1 | physical | 8327460 | |
| TAF1_DROME | Taf1 | physical | 16895980 | |
| TAF5_DROME | Taf5 | physical | 16895980 | |
| TAF6_DROME | Taf6 | physical | 16895980 | |
| TAF9_DROME | e(y)1 | physical | 16895980 | |
| TBP_DROME | Tbp | physical | 16895980 | |
| PHP_DROME | ph-p | physical | 11493925 | |
| TAF9_DROME | e(y)1 | physical | 11493925 | |
| TAF9_DROME | e(y)1 | physical | 12482983 | |
| TAF11_DROME | Taf11 | physical | 8276241 | |
| PSC_DROME | Psc | physical | 11493925 | |
| TBP_DROME | Tbp | physical | 11493925 | |
| TBP_DROME | Tbp | physical | 8327460 | |
| PC_DROME | Pc | physical | 11493925 | |
| TAD2B_DROME | Ada2b | physical | 12482983 | |
| TAF12_DROME | Taf12 | physical | 15456720 | |
| TAF12_DROME | Taf12 | physical | 8276241 | |
| TF2AA_DROME | TfIIA-L | physical | 8224849 | |
| TAF5_DROME | Taf5 | physical | 11493925 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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