TAF11_DROME - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: TAF11_DROME
• UniProt AC: P49906
• Protein Name: Transcription initiation factor TFIID subunit 11
• Gene Name: Taf11
• Organism: Drosophila melanogaster (Fruit fly).
• Sequence Length: 196
• Subcellular Localization: Nucleus.
• Protein Description: TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors..
• Protein Sequence: MDEILFPTQQKSNSLSDGDDVDLKFFQSASGERKDSDTSDPGNDADRDGKDADGDNDNKNTDGDGDSGEPAHKKLKTKKELEEEERERMQVLVSNFTEEQLDRYEMYRRSAFPKAAVKRLMQTITGCSVSQNVVIAMSGIAKVFVGEVVEEALDVMEAQGESGALQPKFIREAVRRLRTKDRMPIGRYQQPYFRLN

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
12	Phosphorylation	LFPTQQKSNSLSDGD CCCCCCCCCCCCCCC	27.58	19429919
14	Phosphorylation	PTQQKSNSLSDGDDV CCCCCCCCCCCCCCC	36.02	19429919
16	Phosphorylation	QQKSNSLSDGDDVDL CCCCCCCCCCCCCCH	39.09	19429919
36	Phosphorylation	ASGERKDSDTSDPGN CCCCCCCCCCCCCCC	45.91	19429919
38	Phosphorylation	GERKDSDTSDPGNDA CCCCCCCCCCCCCCC	38.69	19429919
39	Phosphorylation	ERKDSDTSDPGNDAD CCCCCCCCCCCCCCC	46.96	19429919
67	Phosphorylation	NTDGDGDSGEPAHKK CCCCCCCCCCHHHHH	51.06	19429919
104	Phosphorylation	TEEQLDRYEMYRRSA CHHHHHHHHHHHHCC	12.52	22817900
107	Phosphorylation	QLDRYEMYRRSAFPK HHHHHHHHHHCCCCH	7.31	22817900

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of TAF11_DROME !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of TAF11_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of TAF11_DROME !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
NC2B_DROME	NC2beta	physical	14605208
TAF9_DROME	e(y)1	physical	8276241
TAF11_DROME	Taf11	physical	26257286
TAF2_DROME	Taf2	physical	8276241
AGO2_DROME	AGO2	physical	26257286

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Phosphorylation

"Phosphoproteome analysis of Drosophila melanogaster embryos.";
Zhai B., Villen J., Beausoleil S.A., Mintseris J., Gygi S.P.;
J. Proteome Res. 7:1675-1682(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-14 AND SER-16, AND MASSSPECTROMETRY.
PubMed: 18327897