LKH1_SCHPO - dbPTM
LKH1_SCHPO - PTM Information in dbPTM
Basic Information of Protein
UniProt ID LKH1_SCHPO
UniProt AC Q10156
Protein Name Dual specificity protein kinase lkh1
Gene Name lkh1
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length 690
Subcellular Localization
Protein Description Protein kinase that may act as a negative regulator of filamentous growth and flocculation. Appears to have a role in normal cell wall and septum formation and in cell separation. May have antagonistic function in the regulation of beta-glucan distribution between the sites for cell wall and septum assembly..
Protein Sequence MHSLKRRRNHAPDWQDFYKNGVPQEVIVIEDSASPRLTPNLPPPFSVHQLQSFVPPQPPSSSSPSTTGTVAVPINGANAVYPSTNSVSLPQSYDPWLDANGVVPLPHDVASHPSYMVQSPTSYHACSNNQSPFPHSHHPPLHNPLPVSCQPVLRPPPVPQVPSHWYPVSLPSPNLPHQPISKPPVIPNLPKLQVHPNRLPHPIHNHPYSSPTSYPPPLCPATYCPSNPPQLAPATAIAPSSQSSQHKSVNYSVTPSSINNHTAVPLSPTLAVWLPMTQPTFQPPSANVYQPASNANQVITPVSISDYRPPKKRKRAAWPPYKKVDRVNVPVVHDTTAFDPSTFDDDDGHYKVVPNSKFANRYTVVRLLGHGTFGKVIQCYDQSTGRHCAIKVTRAIPKYREASLIELRVLQTIAHSDPTNENKCIQLRDYFDYRKHICIVTDLFGWSVFDFLKNNNYIPFPLKHIQMLSQQLFKSVAFLHSLGLVHTDLKPENVLLVSNASRTIRLPYRNYSQKVLNSCEIRLIDFGSATFEDEYHSSVVSTRHYRAPEIILGLGWSYPCDVWSIGCILVELFTGQALFQTHEDSEHLCMMEKILGPFDRNMISRSSRTSQRFFKSDGKVRYPLSNTPKKSINYLQSLQTLEQIFAVSSPEVALLLDLLKKVFVYDPKRRITAKEALWHPFFTQPISSNL
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
32PhosphorylationEVIVIEDSASPRLTP
EEEEEECCCCCCCCC
20.1825720772
34PhosphorylationIVIEDSASPRLTPNL
EEEECCCCCCCCCCC
17.9525720772

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of LKH1_SCHPO !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of LKH1_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of LKH1_SCHPO !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
DSK1_SCHPOdsk1genetic
12565823
TUP11_SCHPOtup11physical
20200159
TUP12_SCHPOtup12physical
20200159
GSF2_SCHPOgsf2genetic
22098069
PVG4_SCHPOmbx2genetic
22180499
RUM1_SCHPOrum1physical
23376070
PMP1_SCHPOpmp1physical
23695164
DSK1_SCHPOdsk1genetic
21745468
YDY2_SCHPOSPAC11E3.02cphysical
26167880
YAG9_SCHPOSPAC12G12.09physical
26167880
YAT2_SCHPOSPAC1D4.02cphysical
26167880
THO2_SCHPOtho2physical
26167880
PFD2_SCHPOSPAC227.10physical
26167880
YDG7_SCHPOSPAC26F1.07physical
26167880
YF75_SCHPOspa2physical
26167880
CYK3_SCHPOcyk3physical
26167880
PSA4_SCHPOpre6physical
26167880
YBI8_SCHPOoga1physical
26167880
YBP8_SCHPOSPBC16H5.08cphysical
26167880
YBPC_SCHPOSPBC16H5.12cphysical
26167880
YOP2_SCHPOSPBC418.02physical
26167880
PSA1_SCHPOscl1physical
26167880
YN8E_SCHPOSPBP35G2.14physical
26167880
YC1B_SCHPOmsy1physical
26167880
YCDA_SCHPOSPCC1322.10physical
26167880
SNUT3_SCHPOSPCC162.01cphysical
26167880
YQC1_SCHPOSPCC1739.01physical
26167880
YCV2_SCHPOSPCC777.02physical
26167880
TF211_SCHPOTf2-11physical
26167880
ACT_SCHPOact1physical
26167880
ASE1_SCHPOase1physical
26167880
ASK1_SCHPOask1physical
26167880
VIP1_SCHPOasp1physical
26167880
BYE1_SCHPOSPCC645.13physical
26167880
CDC15_SCHPOcdc15physical
26167880
CIP1_SCHPOcip1physical
26167880
DBP10_SCHPOdbp10physical
26167880
DCP2_SCHPOdcp2physical
26167880
DPH2_SCHPOdph2physical
26167880
MAP2_SCHPOfma2physical
26167880
GAR2_SCHPOgar2physical
26167880
HSP9_SCHPOhsp9physical
26167880
IMP2_SCHPOimp2physical
26167880
LKH1_SCHPOlkh1physical
26167880
MAK2_SCHPOmak2physical
26167880
MDE5_SCHPOmde5physical
26167880
MPR1_SCHPOmpr1physical
26167880
MSH2_SCHPOmsh2physical
26167880
MU123_SCHPOmug123physical
26167880
PIC1_SCHPOpic1physical
26167880
POB1_SCHPOpob1physical
26167880
PP2A2_SCHPOppa2physical
26167880
SF3B1_SCHPOprp10physical
26167880
PRP22_SCHPOprp22physical
26167880
PUB1_SCHPOpub1physical
26167880
RGA7_SCHPOrga7physical
26167880
RGA9_SCHPOrga9physical
26167880
RL34A_SCHPOrpl3401physical
26167880
RL35_SCHPOrpl35physical
26167880
RS26A_SCHPOrps2601physical
26167880
RSD1_SCHPOrsd1physical
26167880
RSV1_SCHPOrsv1physical
26167880
METK_SCHPOsam1physical
26167880
SCE3_SCHPOsce3physical
26167880
SCW1_SCHPOscw1physical
26167880
SET11_SCHPOset11physical
26167880
SNF21_SCHPOsnf21physical
26167880
SNF30_SCHPOsnf30physical
26167880
SPT5_SCHPOspt5physical
26167880
SRW1_SCHPOsrw1physical
26167880
SST6_SCHPOsst6physical
26167880
SUR2_SCHPOsur2physical
26167880
G3P1_SCHPOtdh1physical
26167880
TFH47_SCHPOssl1physical
26167880
THRC_SCHPOSPAC9E9.06cphysical
26167880
IF4G_SCHPOtif471physical
26167880
UBP2_SCHPOubp2physical
26167880
UBP9_SCHPOubp9physical
26167880
VIPI_SCHPOvip1physical
26167880
WIS4_SCHPOwis4physical
26167880
PMP1_SCHPOpmp1physical
26771498

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of LKH1_SCHPO

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Related Literatures of Post-Translational Modification

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