dbPTM

SNF21_SCHPO - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	SNF21_SCHPO
UniProt AC	Q9UTN6
Protein Name	Chromatin structure-remodeling complex subunit snf21
Gene Name	snf21
Organism	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length	1199
Subcellular Localization	Nucleus . Localizes to centromeric and flanking chromatin..
Protein Description	Helicase. Component of the chromatin structure remodeling complex (RSC), which is involved in transcription regulation and nucleosome positioning. Controls particularly membrane and organelle development genes..
Protein Sequence	MRAEKQYTRNEVEETIVRWKKLKESGATEHDNTEYAQLCDVLRSAQSEIEARRDLKGHIKRCFSSVDKNTEKLILKQQVLAYKKLSQNLPAPDDCILSVLLRLSKDEQLLQSIVKQPLQNSKVDGKVRRDFGSCQITPSAKQQRKYLQYQISEDDAIKNRMFRRMSDLESYPAVMRDVAELKDDNERLNLDTIKRNALVELKKLRLIKQQESLRHQVMHCQPHLRTIVNAVERMSCRRPKLVPQATRLTEVLERQQRSDRERRLKQKQCDYLQTVCAHGREINVRTKNAQARAQKANRAVLAYHSHIEKEEQRRAERNAKQRLQALKENDEEAYLKLIDQAKDTRITHLLRQTDHYLDSLAAAVKVQQSQFGESAYDEDMDRRMNPEDDRKIDYYNVAHNIREVVTEQPSILVGGKLKEYQLRGLQWMISLYNNHLNGILADEMGLGKTIQTISLITHLIEKKRQNGPFLVIVPLSTLTNWTMEFERWAPSIVKIVYKGPPQVRKALHPQVRHSNFQVLLTTYEYIIKDRPLLSRIKWIYMIIDEGHRMKNTQSKLTNTLTTYYSSRYRLILTGTPLQNNLPELWALLNFVLPRIFNSIKSFDEWFNTPFANTGGQDKMELTEEESLLVIRRLHKVLRPFLLRRLKKDVEAELPDKVEKVIRCQMSGLQQKLYYQMKKHGMLYVEDAKRGKTGIKGLQNTVMQLKKICNHPFVFEDVERSIDPTGFNYDMLWRVSGKFELLDRILPKLFRSGHRILMFFQMTQIMNIMEDYLHYRQWRYLRLDGSTKADDRSKLLGVFNDPTAEVNLFLLSTRAGGLGLNLQTADTVIIFDSDWNPHQDLQAQDRAHRIGQTKEVRIYRLITEKSVEENILARAQYKLDIDGKVIQAGKFDNKSTPEEREAFLRSLLENENGEEENDEKGELDDDELNEILARGDDELRLFKQMTEDLERESPYGKNKEKERLIQVSELPEFYQREEPEKTTDLLQEEPLGRGARRRTPVVYDEAVRDAQWMAEMDMESEARPTRGRPKRNIASVDETPALTLNGKPKKKRGPAPDTLTSEHRSLLRRVCLEIYKAVNELEDDNGRPLNKLFLELPSKKLYPDYYMIIKSPIALDAIRKHINGTFYKTLEAMKSDLMTMFNNARTYNEEGSFVYEDANKMQTAMETKIEELEEDGTLATLRGMEAEATSQLEDRIENEA

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
952	Phosphorylation	TEDLERESPYGKNKE HHHHHHCCCCCCCHH	29.64	29996109
998	Phosphorylation	GRGARRRTPVVYDEA CCCCCCCCCEECCHH	20.72	28889911

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of SNF21_SCHPO !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of SNF21_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of SNF21_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
RSC1_SCHPO	rsc1	physical	18622392
RSC9_SCHPO	rsc9	physical	18622392
RSC4_SCHPO	rsc4	physical	18622392
SSR1_SCHPO	ssr1	physical	18622392
ARP9_SCHPO	arp9	physical	18622392
SSR2_SCHPO	ssr2	physical	18622392
SSR3_SCHPO	ssr3	physical	18622392
SFH1_SCHPO	sfh1	physical	18622392
RSC58_SCHPO	rsc58	physical	18622392
SSR4_SCHPO	ssr4	physical	18622392
ARP42_SCHPO	arp42	physical	18622392
RSC7_SCHPO	rsc7	physical	18622392

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of SNF21_SCHPO

Related Literatures of Post-Translational Modification