dbPTM

RSC7_SCHPO - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	RSC7_SCHPO
UniProt AC	O94522
Protein Name	Chromatin structure-remodeling complex subunit rsc7
Gene Name	rsc7
Organism	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length	390
Subcellular Localization	Nucleus .
Protein Description	Component of the chromatin structure remodeling complex (RSC), which is involved in transcription regulation and nucleosome positioning. Controls particularly membrane and organelle development genes..
Protein Sequence	MDSTAGSDASTPTNHTVSSKKRRGRPPKGSYAAYGSSDDDDEEYSGRTRRRNRNTRPRVSAPSSSSTVVPKDLYSHRATLEDDELNFGVVDPEGEKKVNELGYLNGGREYRCRTFTCLGRGNRLYMLSTEPARAMGYRDSYLLFLKHRSLHKIIVDDSEKWDLIERNIIPHSYKGRAVGIVAARSIFREFGARIIVGGRRIVDDYWEGEFRARGFVEGELADPDDKLPPPGMPYNRNQYVAWHGASAVYHPQPSLEAQLPAAARKRKKEPPKDATWLFQHAKATAAYNNDITKYLVQKQDIGYFEPHTNLLHVPLNTQPTKTHWIQAKTGTECPAPKLDILVALNSDVAPQVSIANIPPSVYASCPLHVQEAIRKRQEQEIRSIRLNSMY

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
3	Phosphorylation	-----MDSTAGSDAS -----CCCCCCCCCC	20.89	24763107
4	Phosphorylation	----MDSTAGSDAST ----CCCCCCCCCCC	30.67	24763107
7	Phosphorylation	-MDSTAGSDASTPTN -CCCCCCCCCCCCCC	27.78	21712547
10	Phosphorylation	STAGSDASTPTNHTV CCCCCCCCCCCCCCC	39.65	21712547
11	Phosphorylation	TAGSDASTPTNHTVS CCCCCCCCCCCCCCC	35.53	29996109
13	Phosphorylation	GSDASTPTNHTVSSK CCCCCCCCCCCCCCC	39.46	29996109
16	Phosphorylation	ASTPTNHTVSSKKRR CCCCCCCCCCCCCCC	24.93	24763107
18	Phosphorylation	TPTNHTVSSKKRRGR CCCCCCCCCCCCCCC	37.28	24763107
19	Phosphorylation	PTNHTVSSKKRRGRP CCCCCCCCCCCCCCC	37.55	24763107
34	Phosphorylation	PKGSYAAYGSSDDDD CCCCCCCCCCCCCCC	14.90	25720772
36	Phosphorylation	GSYAAYGSSDDDDEE CCCCCCCCCCCCCCC	20.23	28889911
37	Phosphorylation	SYAAYGSSDDDDEEY CCCCCCCCCCCCCCC	40.47	28889911

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of RSC7_SCHPO !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of RSC7_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of RSC7_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
SNF21_SCHPO	snf21	physical	18622392
RSC1_SCHPO	rsc1	physical	18622392
RSC9_SCHPO	rsc9	physical	18622392
RSC4_SCHPO	rsc4	physical	18622392
SSR1_SCHPO	ssr1	physical	18622392
ARP9_SCHPO	arp9	physical	18622392
SSR2_SCHPO	ssr2	physical	18622392
ARP42_SCHPO	arp42	physical	18622392
SSR3_SCHPO	ssr3	physical	18622392
SFH1_SCHPO	sfh1	physical	18622392
RSC58_SCHPO	rsc58	physical	18622392
SSR4_SCHPO	ssr4	physical	18622392

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of RSC7_SCHPO

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"Phosphoproteome analysis of fission yeast."; Wilson-Grady J.T., Villen J., Gygi S.P.; J. Proteome Res. 7:1088-1097(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-36 AND SER-37, AND MASSSPECTROMETRY.	18257517 [Abstract]