RSD1_SCHPO - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: RSD1_SCHPO
• UniProt AC: O13845
• Protein Name: RNA-binding protein rsd1
• Gene Name: rsd1
• Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
• Sequence Length: 603
• Protein Sequence: MQLDAEALAEAPFRKQEVPQNQENQQKASSSFHESSLTSSTHSHPSNPPPPPTRLHDRSFKPVSKNYESEGRLTPPPVSMGYRYARSSKQSFQREDSGYNDDVVTNSSSHRTPRHHRRSYSPRSDYGSRSPSPHSSVDSHQSRSPVRSRDRDRSSRSSRSRHPSSRSRHRYDDYSRSPPYSSRHSRSRRRYEERSSRSSRAHDYDYEDLRDDDRSHERKRSRSRPRERSSKLSEEERDRRTVFVSQLANRLTSRELYDFFEQAGPVRDAQIVRDKISGRSKGVAYVEFCHEDSVQAAIALSGKRLLGLPVIVQLTEAEKNRKAREAAELARAASAEIPFHRLCVSNIHFNLTDEDVKAIFEPFGDIEFVHLQRDDQNRSKGFGYIQYRNPISARNALEKMNGFDLAGRNMRVCLGNDKFTTETTSSMLKRFDETLARQERSQPSQRNGGSSTYESQDYREAAPLSPTEEESRPITRDELMKKLARSEDISDNSKLVSEPEPPIRSRCALLENMFNPAEETSPNWVQELEQDVKEECDEKYGKVVHIAVVPNELGQIFVKFENADFAEKAITGLHQRWFGGRTIKASILPETDYYFKFPNAKTA

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
69	Phosphorylation	PVSKNYESEGRLTPP CCCCCCCCCCCCCCC	34.68	29996109
74	Phosphorylation	YESEGRLTPPPVSMG CCCCCCCCCCCCHHH	32.18	28889911
91	Phosphorylation	YARSSKQSFQREDSG HHHCCCCCCCCCCCC	27.38	25720772
97	Phosphorylation	QSFQREDSGYNDDVV CCCCCCCCCCCCCCC	38.12	29996109
99	Phosphorylation	FQREDSGYNDDVVTN CCCCCCCCCCCCCCC	21.26	28889911
105	Phosphorylation	GYNDDVVTNSSSHRT CCCCCCCCCCCCCCC	29.27	29996109
107	Phosphorylation	NDDVVTNSSSHRTPR CCCCCCCCCCCCCCC	24.69	29996109
108	Phosphorylation	DDVVTNSSSHRTPRH CCCCCCCCCCCCCCC	32.03	29996109
109	Phosphorylation	DVVTNSSSHRTPRHH CCCCCCCCCCCCCCC	19.46	29996109
112	Phosphorylation	TNSSSHRTPRHHRRS CCCCCCCCCCCCCCC	21.17	29996109
130	Phosphorylation	RSDYGSRSPSPHSSV CCCCCCCCCCCCCCC	31.28	29996109
132	Phosphorylation	DYGSRSPSPHSSVDS CCCCCCCCCCCCCCC	36.17	29996109
171	Phosphorylation	SSRSRHRYDDYSRSP CCCCCCCCCCCCCCC	13.67	25720772
174	Phosphorylation	SRHRYDDYSRSPPYS CCCCCCCCCCCCCCC	11.77	28889911
175	Phosphorylation	RHRYDDYSRSPPYSS CCCCCCCCCCCCCCC	33.02	28889911
177	Phosphorylation	RYDDYSRSPPYSSRH CCCCCCCCCCCCCCC	25.04	28889911
450	Phosphorylation	PSQRNGGSSTYESQD CHHCCCCCCCCCCCC	22.39	25720772
451	Phosphorylation	SQRNGGSSTYESQDY HHCCCCCCCCCCCCH	37.98	25720772
465	Phosphorylation	YREAAPLSPTEEESR HHHHCCCCCCCHHHC	28.81	28889911
467	Phosphorylation	EAAPLSPTEEESRPI HHCCCCCCCHHHCCC	53.29	29996109
475	Phosphorylation	EEESRPITRDELMKK CHHHCCCCHHHHHHH	34.45	28889911
497	Phosphorylation	SDNSKLVSEPEPPIR CCCCCCCCCCCCCHH	58.85	25720772

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of RSD1_SCHPO !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of RSD1_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of RSD1_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
RU1A_SCHPO	usp102	physical	22064476

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Phosphorylation

"Phosphoproteome analysis of fission yeast.";
Wilson-Grady J.T., Villen J., Gygi S.P.;
J. Proteome Res. 7:1088-1097(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-174 AND SER-465, ANDMASS SPECTROMETRY.
PubMed: 18257517