| UniProt ID | VPS17_SCHPO | |
|---|---|---|
| UniProt AC | Q9URW7 | |
| Protein Name | Vacuolar protein sorting-associated protein 17 | |
| Gene Name | vps17 | |
| Organism | Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast). | |
| Sequence Length | 549 | |
| Subcellular Localization | Cytoplasm . Nucleus . | |
| Protein Description | Plays a role in vesicular protein sorting. Required for the endosome-to-Golgi retrieval of the vacuolar protein sorting receptor pep1/vps10. Component of the membrane-associated retromer complex which is essential in endosome-to-Golgi retrograde transport. The vps29-vps26-vps35 subcomplex may be involved in cargo selection.. | |
| Protein Sequence | MSSQHSTDDLMNSHVFSGGFSTLDDKGFQDVPIHTDMPGSISVEPSSEDANVGSVNGNINETPVFEADRLIAEATMNPSAASSTTGENSISQTGSGPFLRIRIVDIEAENSKDPVIKMNVQTTLPAYRSKLYKNVRRTHAEFKKFAKYLISTHPECLIPAVPEAKTSVSSGIKEDLIYLKSGLQSWLNYVSTNPNLLYDPELQLFVESDYGYSPLINTGNPTSGLKRKALKQFPLPPDPCQALANLRPIVKSFYKNAKDAEIKLEKLVNRKQSLALTHADLGQSLIDYSVEEQHNGLANALNRVGKMLQAISDVRIMQSSKQLVTLADSLCYASDNAFVVKEILSNRHILMRDLISSKNQTNSYLSAANRLQDSPKISKARTDDALQALEVARVHEKLLSDKVDFVTLNLVKESKTYTKKTSVSLQKAIREYVEKEAYYERRLLSIMESIRPHIRNIDPFGGLSRLGREEYPRRLSNPPPSQKTNQDAWTNRKRPGYSSSFDGSSQSTFNPSNNDGAHNTSENADELVEPPIGNERLDPKSVANLLNAI | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 2 | Phosphorylation | ------MSSQHSTDD ------CCCCCCHHH | 38.41 | 24763107 | |
| 3 | Phosphorylation | -----MSSQHSTDDL -----CCCCCCHHHH | 30.52 | 24763107 | |
| 6 | Phosphorylation | --MSSQHSTDDLMNS --CCCCCCHHHHHHC | 26.37 | 24763107 | |
| 7 | Phosphorylation | -MSSQHSTDDLMNSH -CCCCCCHHHHHHCC | 31.26 | 28889911 | |
| 13 | Phosphorylation | STDDLMNSHVFSGGF CHHHHHHCCCCCCCC | 13.68 | 21712547 | |
| 17 | Phosphorylation | LMNSHVFSGGFSTLD HHHCCCCCCCCCCCC | 36.60 | 21712547 | |
| 79 | Phosphorylation | AEATMNPSAASSTTG EEHHCCCCCCCCCCC | 31.31 | 25720772 | |
| 82 | Phosphorylation | TMNPSAASSTTGENS HCCCCCCCCCCCCCC | 28.12 | 25720772 | |
| 83 | Phosphorylation | MNPSAASSTTGENSI CCCCCCCCCCCCCCC | 25.84 | 25720772 | |
| 84 | Phosphorylation | NPSAASSTTGENSIS CCCCCCCCCCCCCCC | 36.00 | 25720772 | |
| 85 | Phosphorylation | PSAASSTTGENSISQ CCCCCCCCCCCCCCC | 44.43 | 25720772 | |
| 364 | Phosphorylation | SKNQTNSYLSAANRL CCHHHHHHHHHHHHH | 13.52 | 21712547 | |
| 374 | Phosphorylation | AANRLQDSPKISKAR HHHHHCCCCCHHCCC | 18.35 | 24763107 | |
| 464 | Phosphorylation | IDPFGGLSRLGREEY CCCCCCCHHCCCCCC | 28.83 | 25720772 | |
| 476 | Phosphorylation | EEYPRRLSNPPPSQK CCCCHHHCCCCCCCC | 45.54 | 28889911 | |
| 541 | Phosphorylation | NERLDPKSVANLLNA CCCCCHHHHHHHHHC | 31.67 | 25720772 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of VPS17_SCHPO !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of VPS17_SCHPO !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of VPS17_SCHPO !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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