dbPTM

BRO1_SCHPO - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	BRO1_SCHPO
UniProt AC	O13783
Protein Name	Vacuolar protein-sorting protein bro1
Gene Name	bro1
Organism	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length	775
Subcellular Localization	Cytoplasm. Endosome.
Protein Description	Involved in concentration and sorting of cargo proteins of the multivesicular body (MVB) for incorporation into intralumenal vesicles..
Protein Sequence	MEKLATPFFYLNKKETKHSDWVEPFTTFVSRIYGNSVDVEDQIKAFNTLRENAADVDDTVAGKDILYSYYGQLDYLSFRFPTGGNGINISFEWSDILDPDADFVKQSSLAFEKASVLFNLVSLLSRMAANHASAYTVDDYKAAANCLQCASGIAKLLRESFIHAPGRDLDSNFLLGIYNLFLGQAQECVLGHMSFSASDSNMNYSLAAKIASSAATLYDSCVHAFESMEPACNPNFIRLASAKKAALEGFSSYFMARAQLEKSKQGLAIGYLQQAKSILSSAQKLFNGIKLSTDFIHKPSLSDYPQTISTFIKSSLSHLLKTAEKDNDFVFHDLVVKEVELPKISPLQALPPLPLEKLYGSQDGFETAKKIVGDDLFKAFVPSAVTTASSLYSEETAKVFRAEQAEVERQNTQMATVFASLDLSRLQEITHSDSKTNFIPKELIEARSQLISFNPTFKIHELFAKSTKLKQIIAKIKSDLEVEANENAKMKAKLGPSWTLSDSLEFAAPYQSELNNYLKTLAEASATDSAISQQYALVKDDVETLCNSSKISALLESSISSTDNSGQSLLDIPIEQEEQERDMKIQLDLLEELQSRVQKLVPERQTTLQALQQKCLQDDISESLMQNSKRKDSALDTNQLFELELKKFDPLRNRLHASYRQQQLLLNEMRNVTQKLKQNPEFLRKMEVYNNQFSKNKELCSNLLSSSLTAKAISEGVSKGLEYYKTVEQRLAEINKTLGEQLLLRRKQGATCLSKLSSSSSSHTSISSNMRNLHI

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
263	Phosphorylation	ARAQLEKSKQGLAIG HHHHHHHHHHHHHHH	22.34	25720772
761	Phosphorylation	SKLSSSSSSHTSISS HHHCCCCCCCCCCCC	28.25	25720772
765	Phosphorylation	SSSSSHTSISSNMRN CCCCCCCCCCCCCCC	18.30	25720772

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of BRO1_SCHPO !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of BRO1_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of BRO1_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of BRO1_SCHPO !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of BRO1_SCHPO

Related Literatures of Post-Translational Modification