dbPTM

VPS8_SCHPO - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	VPS8_SCHPO
UniProt AC	O13756
Protein Name	Vacuolar protein sorting-associated protein 8
Gene Name	vps8
Organism	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length	1272
Subcellular Localization	Golgi apparatus . Cytoplasm .
Protein Description	Involved in the retention of proteins to the late-Golgi. Plays an integral role in the complex vacuolar protein sorting process (By similarity)..
Protein Sequence	MQSKYGRSSLKIKNGDDTRTLRALSFSKDSVNSSSFDNEAASTTLGISTAIHASNRPFRQDEYSWNDCWMRWGQLRRVSSQLRELRFTMNDQPATVTSIAYQGTLLVAGTSSGHVLLNDWRTNDFQILKPGLSSNESVTLPVTSLAISNSKRIVCQGHAGGIIFVWDVSRKPPLQLFTINQHSEDSVLTHLVFNGNSDDVLLSTDHLGKIAVHEFYNLVINKHCTSWNLDMSKSNSLNLDSIIVDTSSISFEELHITGVKHFSFVVLQSLQSIQIVTLFPKTTLIYEFKYPAGIVSSACHSFSSSIVHKNGENTKLHAFFATAYNNNLRLYSVTFHKGYMSLQLMDRKKFAKAIWKLWWFPSSSIIIILFDDMELAFVNSMSLDIIGTSTILDKSLLRWDWYSNSLAAIGVSQTVFPFISSSLCISPRYMFVVNSETVSVGSFLMVSEQLQMLSERYGFFDSIKFGSYCVSNLSIFPKLLLEKTSVINLIMALYVKLLKSLARDFPARSPFEATSQKTNDYELEVQHLFTWTCELYSENFNTVISSFIIANSLGILPEIIEQIIPVFTRVGKVYVVLEALFDLILSQRFTNPSPQLQHHILNYLNDCKRLQDMDKLIPCIEYQSLDLDFITKFSRSKGLFDSLCYVSIYAFNDYSIPLVQFLNLLKSDIDSPSEETSINVEKGFHFLLYSLTGMKYPLGHSNNINDAYVVIHTLLKVIFSVVPLPFDVPVDNSVDFPYLRLFLEKHADDFFRCLEVAFDYPYFSLEKVTIAKKLLDTVNRQWILECISQLYEKKKSVSQSYYIFVSHVTANYSNQLLFSQSFYQGILDGLCNIDVPDDKREVVEAAIEELLTVYEHFDIATTLLSCWDHQLYQVILHISFKCGRYEDYIEAILALWKQKGQKHSFVSESSEALISLVFNNLQTINRFPGHRERYVSTLISHCGDLFAINHVCFVRNSLKYLLDDFTKVITKTFSIKSIRLQFLSLIIYEITYEQLSSWYRERTILSFLELVSFDQGDVKMLELLRLHPKLVRLQGLMEILNKNDCIESCIFVYRELAEYKLALSHVSKYIEKSMSVFDLEKSDDMTSRRIERLCLHLKTVVPLFEQCTKEVSAEDVTNFWLELVFTLLLVYIKLSLKGSINSQITFKDFQQELSLCIENLLDSFLSKTNSYKIALNTVLVRICEEASRNEHSDQYLRKLLLKLITDLYINHDITKECFLLWDMKQFYEIRSTLLQNASGVLVEDPKLQKNAKGQYTSKLKVYFSGLIEREDL

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
18	Phosphorylation	KIKNGDDTRTLRALS EEECCCCHHHEEEEE	30.23	21712547
20	Phosphorylation	KNGDDTRTLRALSFS ECCCCHHHEEEEEEC	23.76	21712547
25	Phosphorylation	TRTLRALSFSKDSVN HHHEEEEEECCCCCC	26.87	21712547
27	Phosphorylation	TLRALSFSKDSVNSS HEEEEEECCCCCCCC	31.98	21712547
79	Phosphorylation	WGQLRRVSSQLRELR HHHHHHHHHHHHHHH	15.56	25720772

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of VPS8_SCHPO !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of VPS8_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of VPS8_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of VPS8_SCHPO !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of VPS8_SCHPO

Related Literatures of Post-Translational Modification