RRN11_YEAST - dbPTM
RRN11_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID RRN11_YEAST
UniProt AC Q04712
Protein Name RNA polymerase I-specific transcription initiation factor RRN11
Gene Name RRN11
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 507
Subcellular Localization Nucleus, nucleolus .
Protein Description Acts as component of the core factor (CF) complex which is essential for the initiation of rDNA transcription by RNA polymerase I. After binding of UAF (upstream activation factor) to an upstream element of the promoter, CF is recruited in a SPT15/TBP-dependent manner to form a preinitiation complex..
Protein Sequence MFEVPITLTNRKFAQRRKLKYQYINYISRRFDRISKKSTTTDSLPTPENSAAENNDEEEGQNSEAGTYRRSVLQQKKRRRERHWRSVVGEIYSTTESETDSQEEETEEGGEHDTGIDKEDSDEERKFWKKYEKPEKSFEIWRTVSSQNKQPINKQKMTYHNFKKIEKIPLRKMEIPLLHCTKENKLYFQSISRGLEPLKTSTSEVRNYRTRHIVTLTDLLHLNVSRHNWSLAYKIFATLIRIPGVQIKSLWGIGVEILDNLSNSSSGLDFLQWMCQIYSSKSRFVQNINYRSIVPPFQTGSRTHTAKFAITYLWSSLINCQKSMEPSSNIIDKPFDTENDLLQELIDKISEWVLTPPFMEDAEVWFIYASCHLLKADTLSRQFVNDNKNNDLIGLDRDIKINQVIKHIHYVRTFLKICLDKGGFAVPSRLIENQLKSFESRLYGEAQDIQERDVANVYDSIDNSSVENSFGDVYETNAEFLDTQLMDLSPEDNGLDEMHYSDEDSSE
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
215PhosphorylationYRTRHIVTLTDLLHL
HCCEEEEEHHHHHCC		24.2819779198
217PhosphorylationTRHIVTLTDLLHLNV
CEEEEEHHHHHCCCC		18.4219779198
225PhosphorylationDLLHLNVSRHNWSLA
HHHCCCCCCCCHHHH		27.0919779198
413PhosphorylationKHIHYVRTFLKICLD
HHHHHHHHHHHHHHC		24.2329688323
428PhosphorylationKGGFAVPSRLIENQL
CCCCCCCHHHHHHHH		32.8729688323
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of RRN11_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of RRN11_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of RRN11_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
RRN11_YEASTRRN11physical
8702872
RRN6_YEASTRRN6physical
8702872
RRN7_YEASTRRN7physical
8702872
RRN6_YEASTRRN6physical
8887672
RRN6_YEASTRRN6physical
16554755
ATG17_YEASTATG17physical
18719252
GCR2_YEASTGCR2physical
18719252
RRN6_YEASTRRN6physical
25132180
RRN7_YEASTRRN7physical
25132180
TBP_YEASTSPT15physical
25132180
CHK1_YEASTCHK1genetic
27708008
ATG15_YEASTATG15genetic
27708008
ASK10_YEASTASK10genetic
27708008
YL278_YEASTYLR278Cgenetic
27708008
NOP12_YEASTNOP12genetic
27708008
APC11_YEASTAPC11genetic
27708008
RSP5_YEASTRSP5genetic
27708008
ACT_YEASTACT1genetic
27708008
SAD1_YEASTSAD1genetic
27708008
PRP19_YEASTPRP19genetic
27708008
TAD3_YEASTTAD3genetic
27708008
GPI12_YEASTGPI12genetic
27708008
HAS1_YEASTHAS1genetic
27708008
GPI2_YEASTGPI2genetic
27708008
YAJ9_YEASTYAR029Wgenetic
27708008
HIR1_YEASTHIR1genetic
27708008
RL23A_YEASTRPL23Agenetic
27708008
RL23B_YEASTRPL23Agenetic
27708008
SHG1_YEASTSHG1genetic
27708008
YCQ6_YEASTYCR016Wgenetic
27708008
GPR1_YEASTGPR1genetic
27708008
INO2_YEASTINO2genetic
27708008
PLP1_YEASTPLP1genetic
27708008
HSP78_YEASTHSP78genetic
27708008
RS26B_YEASTRPS26Bgenetic
27708008
VAM7_YEASTVAM7genetic
27708008
RS25A_YEASTRPS25Agenetic
27708008
YG1X_YEASTYGR050Cgenetic
27708008
TBP7_YEASTYTA7genetic
27708008
PAU13_YEASTPAU13genetic
27708008
AIM18_YEASTAIM18genetic
27708008
MOG1_YEASTMOG1genetic
27708008
UBP11_YEASTUBP11genetic
27708008
POC3_YEASTIRC25genetic
27708008
RAD5_YEASTRAD5genetic
27708008
ERG3_YEASTERG3genetic
27708008
NAH1_YEASTNHA1genetic
27708008
DPH6_YEASTDPH6genetic
27708008
METK1_YEASTSAM1genetic
27708008
SWI6_YEASTSWI6genetic
27708008
MMR1_YEASTMMR1genetic
27708008
YL287_YEASTYLR287Cgenetic
27708008
COX8_YEASTCOX8genetic
27708008
SEI1_YEASTFLD1genetic
27708008
RS3A1_YEASTRPS1Agenetic
27708008
RL6B_YEASTRPL6Bgenetic
27708008
PET8_YEASTPET8genetic
27708008
HRB1_YEASTHRB1genetic
27708008
TPM1_YEASTTPM1genetic
27708008
PMS1_YEASTPMS1genetic
27708008
MKT1_YEASTMKT1genetic
27708008
INO4_YEASTINO4genetic
27708008
HAP5_YEASTHAP5genetic
27708008
RAD1_YEASTRAD1genetic
27708008
YP109_YEASTYPL109Cgenetic
27708008
YP022_YEASTYPR022Cgenetic
27708008
CCDB1_HUMANCCNDBP1physical
27107014
MARE3_HUMANMAPRE3physical
27107014
CEP63_HUMANCEP63physical
27107014
ADIP_HUMANSSX2IPphysical
27107014
NEMO_HUMANIKBKGphysical
27107014
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of RRN11_YEAST

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Related Literatures of Post-Translational Modification

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