NDUAB_HUMAN - dbPTM
NDUAB_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID NDUAB_HUMAN
UniProt AC Q86Y39
Protein Name NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11
Gene Name NDUFA11
Organism Homo sapiens (Human).
Sequence Length 141
Subcellular Localization Mitochondrion inner membrane
Multi-pass membrane protein
Matrix side .
Protein Description Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone..
Protein Sequence MAPKVFRQYWDIPDGTDCHRKAYSTTSIASVAGLTAAAYRVTLNPPGTFLEGVAKVGQYTFTAAAVGAVFGLTTCISAHVREKPDDPLNYFLGGCAGGLTLGARTHNYGIGAAACVYFGIAASLVKMGRLEGWEVFAKPKV
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
2Acetylation------MAPKVFRQY
------CCCCHHHHH		16.7812381726
9PhosphorylationAPKVFRQYWDIPDGT
CCCHHHHHCCCCCCC		10.7829496907
21UbiquitinationDGTDCHRKAYSTTSI
CCCCCCHHHCCCCHH		28.1922817900
21 (in isoform 2)Ubiquitination-28.1921906983
21 (in isoform 1)Ubiquitination-28.1921890473
24PhosphorylationDCHRKAYSTTSIASV
CCCHHHCCCCHHHHH		30.0329496907
27PhosphorylationRKAYSTTSIASVAGL
HHHCCCCHHHHHHCH		19.0829496907
83 (in isoform 2)Ubiquitination-43.0921906983
83 (in isoform 1)Ubiquitination-43.0921890473
83UbiquitinationISAHVREKPDDPLNY
HHHHHHCCCCCCCHH		43.0983
117PhosphorylationIGAAACVYFGIAASL
CCHHHHHHHHHHHHH		8.9327642862
123PhosphorylationVYFGIAASLVKMGRL
HHHHHHHHHHHCCCC		25.3624719451
138UbiquitinationEGWEVFAKPKV----
CCCEEECCCCC----		33.6327667366
138 (in isoform 1)Ubiquitination-33.6321890473
140UbiquitinationWEVFAKPKV------
CEEECCCCC------		60.93-
167 (in isoform 2)Phosphorylation-22210691
168 (in isoform 2)Phosphorylation--
169 (in isoform 2)Phosphorylation-22210691
178 (in isoform 2)Phosphorylation-22210691
198 (in isoform 2)Phosphorylation-25262027
209 (in isoform 2)Phosphorylation--
217 (in isoform 2)Phosphorylation--
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of NDUAB_HUMAN !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of NDUAB_HUMAN !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of NDUAB_HUMAN !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
NDUA9_HUMANNDUFA9physical
24344204
NDUA8_HUMANNDUFA8physical
24344204
NIT1_HUMANNIT1physical
24344204
NU5M_HUMANND5physical
24344204
NDUA6_HUMANNDUFA6physical
24344204
NDUV3_HUMANNDUFV3physical
24344204
YMEL1_HUMANYME1L1physical
24344204
NDUV2_HUMANNDUFV2physical
24344204
NDUS4_HUMANNDUFS4physical
24344204
NDUB6_HUMANNDUFB6physical
24344204
GHITM_HUMANGHITMphysical
24344204
PCKGC_HUMANPCK1physical
24344204
NDUB8_HUMANNDUFB8physical
24344204
NDUS2_HUMANNDUFS2physical
24344204
NDUA5_HUMANNDUFA5physical
24344204
NDUB3_HUMANNDUFB3physical
24344204
AFG32_HUMANAFG3L2physical
24344204
QCR9_HUMANUQCR10physical
24344204
NDUAA_HUMANNDUFA10physical
24344204
NDUS1_HUMANNDUFS1physical
24344204
NDUB4_HUMANNDUFB4physical
24344204
NDUA2_HUMANNDUFA2physical
24344204
NDUB5_HUMANNDUFB5physical
24344204
UCRI_HUMANUQCRFS1physical
24344204
NDUV1_HUMANNDUFV1physical
24344204
COX5B_HUMANCOX5Bphysical
24344204
NDUBB_HUMANNDUFB11physical
24344204
QCR7_HUMANUQCRBphysical
24344204
NDUS3_HUMANNDUFS3physical
24344204
NDUAC_HUMANNDUFA12physical
24344204
RM44_HUMANMRPL44physical
24344204
NU4M_HUMANND4physical
24344204
NDUS7_HUMANNDUFS7physical
24344204
ACPM_HUMANNDUFAB1physical
24344204
NU2M_HUMANND2physical
24344204
NDUS6_HUMANNDUFS6physical
24344204
NDUS8_HUMANNDUFS8physical
24344204
NDUS5_HUMANNDUFS5physical
24344204
Drug and Disease Associations
Kegg Disease
H00473 Mitochondrial respiratory chain deficiencies (MRCD), including: Mitochondrial complex I deficiency (
OMIM Disease
252010Mitochondrial complex I deficiency (MT-C1D)
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of NDUAB_HUMAN

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Related Literatures of Post-Translational Modification

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