ISC10_YEAST - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ISC10_YEAST
• UniProt AC: P32645
• Protein Name: Meiosis-specific protein ISC10
• Gene Name: ISC10
• Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
• Sequence Length: 267
• Protein Description: Indispensable for spore formation..
• Protein Sequence: MDVDERLHQDENQTHPFSQKKSSSFLIKEKAATKSKDLEHIRLRDLNFNHRKKLDDKKLAKQIPVKANFKKPNEIEARANLNSNELTDINLDYIPDSPSIEKISGPEDSIVVTPRNIIHLQSDSDIILEECEHNYDCSPFYRLFNYENRIEPDDYEAIINAIITDEIAGTYPVFERELEYQELKSLVRKRDYIMYYFLSRDYRGFFQLKEERTLFYRYPSIAYTSPLRYLDNGSETEQFTGDDDEELQSFDFENTSSVRTLDSNIWR

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
102	Ubiquitination	PDSPSIEKISGPEDS CCCCCHHHCCCCCCC	40.27	17644757
109	Phosphorylation	KISGPEDSIVVTPRN HCCCCCCCEEECCCC	18.67	27214570
113	Phosphorylation	PEDSIVVTPRNIIHL CCCCEEECCCCEEEE	12.97	27214570

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ISC10_YEAST !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ISC10_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ISC10_YEAST !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
TRP_YEAST	TRP5	physical	10688190
DIG1_YEAST	DIG1	physical	18719252
MTU1_YEAST	SLM3	genetic	27708008
MZM1_YEAST	MZM1	genetic	27708008
TNA1_YEAST	TNA1	genetic	27708008
PIH1_YEAST	PIH1	genetic	27708008
KTR7_YEAST	KTR7	genetic	27708008
EOS1_YEAST	EOS1	genetic	27708008
MSO1_YEAST	MSO1	genetic	27708008
IZH2_YEAST	IZH2	genetic	27708008
CISY3_YEAST	CIT3	genetic	27708008
YP063_YEAST	YPR063C	genetic	27708008
PPAL_YEAST	LTP1	genetic	27708008
YP089_YEAST	YPR089W	genetic	27708008
SUE1_YEAST	SUE1	genetic	27708008
HDA3_YEAST	HDA3	genetic	27708008
ERV46_YEAST	ERV46	genetic	27708008
NUP60_YEAST	NUP60	genetic	27708008
YBR2_YEAST	YBR062C	genetic	27708008
TOS1_YEAST	TOS1	genetic	27708008
AIM4_YEAST	AIM4	genetic	27708008
KCC4_YEAST	KCC4	genetic	27708008
AGP1_YEAST	AGP1	genetic	27708008
PBP4_YEAST	PBP4	genetic	27708008
MCH1_YEAST	MCH1	genetic	27708008
TRM3_YEAST	TRM3	genetic	27708008
YD157_YEAST	YDL157C	genetic	27708008
YSP2_YEAST	YSP2	genetic	27708008
PKH3_YEAST	PKH3	genetic	27708008
APA2_YEAST	APA2	genetic	27708008
IOC3_YEAST	IOC3	genetic	27708008
ARO8_YEAST	ARO8	genetic	27708008
YG21_YEAST	YGR053C	genetic	27708008
BTN2_YEAST	BTN2	genetic	27708008
HTD2_YEAST	HTD2	genetic	27708008
CHS7_YEAST	CHS7	genetic	27708008
VPS53_YEAST	VPS53	genetic	27708008
GSH1_YEAST	GSH1	genetic	27708008
IME2_YEAST	IME2	genetic	27708008
IF4A_YEAST	TIF2	genetic	27708008
CBF1_YEAST	CBF1	genetic	27708008
SFC1_YEAST	SFC1	genetic	27708008
RIC1_YEAST	RIC1	genetic	27708008
YL053_YEAST	YLR053C	genetic	27708008
ACE2_YEAST	ACE2	genetic	27708008
NKP2_YEAST	NKP2	genetic	27708008
YL446_YEAST	YLR446W	genetic	27708008
ASND1_YEAST	YML096W	genetic	27708008
GID8_YEAST	GID8	genetic	27708008
YM24_YEAST	YMR147W	genetic	27708008
SSO2_YEAST	SSO2	genetic	27708008
HSC82_YEAST	HSC82	genetic	27708008
ZRC1_YEAST	ZRC1	genetic	27708008
NM111_YEAST	NMA111	genetic	27708008
AIM39_YEAST	AIM39	genetic	27708008
RTG1_YEAST	RTG1	genetic	27708008
VPS68_YEAST	VPS68	genetic	27708008
RL21B_YEAST	RPL21B	genetic	27708008
SPEE_YEAST	SPE3	genetic	27708008

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.