| UniProt ID | ARNT2_HUMAN | |
|---|---|---|
| UniProt AC | Q9HBZ2 | |
| Protein Name | Aryl hydrocarbon receptor nuclear translocator 2 | |
| Gene Name | ARNT2 | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 717 | |
| Subcellular Localization | Nucleus . | |
| Protein Description | Transcription factor that plays a role in the development of the hypothalamo-pituitary axis, postnatal brain growth, and visual and renal function. [PubMed: 24022475 Specifically recognizes the xenobiotic response element (XRE] | |
| Protein Sequence | MATPAAVNPPEMASDIPGSVTLPVAPMAATGQVRMAGAMPARGGKRRSGMDFDDEDGEGPSKFSRENHSEIERRRRNKMTQYITELSDMVPTCSALARKPDKLTILRMAVSHMKSMRGTGNKSTDGAYKPSFLTEQELKHLILEAADGFLFVVAAETGRVIYVSDSVTPVLNQPQSEWFGSTLYEQVHPDDVEKLREQLCTSENSMTGRILDLKTGTVKKEGQQSSMRMCMGSRRSFICRMRCGNAPLDHLPLNRITTMRKRFRNGLGPVKEGEAQYAVVHCTGYIKAWPPAGMTIPEEDADVGQGSKYCLVAIGRLQVTSSPVCMDMNGMSVPTEFLSRHNSDGIITFVDPRCISVIGYQPQDLLGKDILEFCHPEDQSHLRESFQQVVKLKGQVLSVMYRFRTKNREWMLIRTSSFTFQNPYSDEIEYIICTNTNVKQLQQQQAELEVHQRDGLSSYDLSQVPVPNLPAGVHEAGKSVEKADAIFSQERDPRFAEMFAGISASEKKMMSSASAAGTQQIYSQGSPFPSGHSGKAFSSSVVHVPGVNDIQSSSSTGQNMSQISRQLNQSQVAWTGSRPPFPGQQIPSQSSKTQSSPFGIGTSHTYPADPSSYSPLSSPATSSPSGNAYSSLANRTPGFAESGQSSGQFQGRPSEVWSQWQSQHHGQQSGEQHSHQQPGQTEVFQDMLPMPGDPTQGTGNYNIEDFADLGMFPPFSE | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
|
|
||
* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 3 (in isoform 2) | Phosphorylation | - | 16.50 | 29116813 | |
| 14 | Phosphorylation | VNPPEMASDIPGSVT CCCHHHHCCCCCCEE | 34.46 | 26503514 | |
| 19 | Phosphorylation | MASDIPGSVTLPVAP HHCCCCCCEEECCCC | 13.43 | 24043423 | |
| 21 | Phosphorylation | SDIPGSVTLPVAPMA CCCCCCEEECCCCCC | 27.35 | 24043423 | |
| 30 | Phosphorylation | PVAPMAATGQVRMAG CCCCCCCCCCCEECC | 20.71 | 26503514 | |
| 42 | Methylation | MAGAMPARGGKRRSG ECCCCCCCCCCCCCC | 48.83 | - | |
| 69 | Phosphorylation | KFSRENHSEIERRRR HHCCCCHHHHHHHHH | 52.42 | 29083192 | |
| 80 | Phosphorylation | RRRRNKMTQYITELS HHHHHHHHHHHHHHH | 21.60 | 28348404 | |
| 82 | Phosphorylation | RRNKMTQYITELSDM HHHHHHHHHHHHHHH | 10.72 | 28348404 | |
| 84 | Phosphorylation | NKMTQYITELSDMVP HHHHHHHHHHHHHHC | 26.41 | 28348404 | |
| 87 | Phosphorylation | TQYITELSDMVPTCS HHHHHHHHHHHCHHH | 19.89 | 28348404 | |
| 92 | Phosphorylation | ELSDMVPTCSALARK HHHHHHCHHHHHCCC | 14.00 | 28348404 | |
| 94 | Phosphorylation | SDMVPTCSALARKPD HHHHCHHHHHCCCCC | 28.88 | 28348404 | |
| 104 | Phosphorylation | ARKPDKLTILRMAVS CCCCCHHHHHHHHHH | 24.57 | 29083192 | |
| 111 | Phosphorylation | TILRMAVSHMKSMRG HHHHHHHHHHHHHCC | 14.34 | 29083192 | |
| 115 | Phosphorylation | MAVSHMKSMRGTGNK HHHHHHHHHCCCCCC | 13.21 | 29083192 | |
| 214 | Ubiquitination | TGRILDLKTGTVKKE CCEEEEECCCCEEEC | 44.57 | - | |
| 225 | Phosphorylation | VKKEGQQSSMRMCMG EEECCCHHHHCHHHC | 20.43 | 23403867 | |
| 226 | Phosphorylation | KKEGQQSSMRMCMGS EECCCHHHHCHHHCC | 13.18 | 22210691 | |
| 233 | Phosphorylation | SMRMCMGSRRSFICR HHCHHHCCCCCEEEC | 9.53 | 23403867 | |
| 236 | Phosphorylation | MCMGSRRSFICRMRC HHHCCCCCEEECCCC | 20.18 | 24719451 | |
| 309 | Phosphorylation | DVGQGSKYCLVAIGR CCCCCCCEEEEEEEC | 7.85 | 27642862 | |
| 488 | Phosphorylation | EKADAIFSQERDPRF HHHHHHHCCCCCHHH | 25.64 | 24719451 | |
| 507 | Acetylation | AGISASEKKMMSSAS HCCCHHHHHHHHCHH | 43.40 | 7481521 | |
| 540 | Phosphorylation | SGKAFSSSVVHVPGV CCCCCCCEEEECCCC | 27.28 | - | |
| 578 | Methylation | QVAWTGSRPPFPGQQ CCCCCCCCCCCCCCC | 44.23 | - | |
| 588 | Phosphorylation | FPGQQIPSQSSKTQS CCCCCCCCCCCCCCC | 44.30 | - | |
| 614 | Phosphorylation | PADPSSYSPLSSPAT CCCHHHCCCCCCCCC | 22.70 | 18669648 | |
| 621 | Phosphorylation | SPLSSPATSSPSGNA CCCCCCCCCCCCCCH | 32.87 | 18669648 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of ARNT2_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of ARNT2_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of ARNT2_HUMAN !! | ||||||
| Kegg Disease | ||||||
|---|---|---|---|---|---|---|
| There are no disease associations of PTM sites. | ||||||
| OMIM Disease | ||||||
| 615926 | Webb-Dattani syndrome (WEDAS) | |||||
| Kegg Drug | ||||||
| There are no disease associations of PTM sites. | ||||||
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
loading...
