| UniProt ID | EGL15_CAEEL | |
|---|---|---|
| UniProt AC | Q10656 | |
| Protein Name | Myoblast growth factor receptor egl-15 | |
| Gene Name | egl-15 | |
| Organism | Caenorhabditis elegans. | |
| Sequence Length | 1040 | |
| Subcellular Localization |
Membrane Single-pass type I membrane protein. |
|
| Protein Description | Receptor tyrosine kinase required for larval development. [PubMed: 7585964 May phosphorylate adapter protein soc-1 which in turn may result in the recruitment and/or activation of phosphatase ptp-2] | |
| Protein Sequence | MSYFLASCLGVGLLSTVSCSLQGLTSHYRENIPRFKHVANERYEVFLGDEIKFDCQTAASKISAFVEWYRNDKLLKNDQIDKDKIRKDNNRMMLHLKNIDVSDQGLWSCRVHNAYGQISRNFTVEVIDFCDYFLFPDIHHLNIPMECVCLWKYNKEAKRSDVNYAAVTGEVCSKYASRMINRARKPLPMIPCFGDHCKEFDTTPVSDFGLPGKPEDDPLVKRVVLKKDDVIVPVHDSEESPSESRTEFINADEKENKEDEEEDYSVSQPVAPDAGLTELNITAEEPPYFKSNDNIVLFNETHALPAGRTLKLNCRAKGYPEPQIIWYKNGKMLKKSSARSGGYEFKFNRWSLEVEDAVVADSGEFHCEALNKVGSAKKYFHVIIVNRMRRPPIIVPNILANQSVNINDTATFHCKVVSDLLPHIIWVRINKINGSYSYYNNSAEEYMFNYTEMDTFDKAHVHHVGDESTLTIFNVSLDDQGIYACLSGNSLGMSMANATLTVNEFMAIHLLTGDEPKIDRWTTSDYIFTTILLFLLLAATLFGILFMVCKQTLHKKGFMDDTVGLVARKKRVVVSKRPMNEDNENSDDEPSPYQIQIIETPITKKEAARKQRKRMNSENTVLSEYEVDSDPVWEVERSKLSLVHMLGEGAFGEVWKATYKETENNEIAVAVKKLKMSAHEKELIDLVSEMETFKVIGEHENVLRLIGCCTGAGPLYVVVELCKHGNLRDFLRAHRPKEEKAKKSSQELTDYLEPRKASDKDDIELIPNLTQRHLVQFAWQVAQGMNFLASKKIIHRDLAARNVLVGDGHVLKISDFGLSRDVHCNDYYRKRGNGRLPIKWMALEALDSNVYTVESDVWSYGVLLWEIMTLGGTPYPTIAMPELYANLKEGYRMEPPHLCPQEVYHLMCSCWREKLEERPSFKTIVDYLDWMLTMTNETIEGSQEFNDQFFSERSTASGPVSPMESFQKKRKHRPLSAPVNLPSEPQHTICDDYESNFSVEPPNDPNHLYCNDNMLKNHIITPETSQRIPSNNNSMSKPEF | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 121 | N-linked_Glycosylation | AYGQISRNFTVEVID CCCCCCCCEEEEEEE | 30.10 | - | |
| 237 | Phosphorylation | VIVPVHDSEESPSES EEEECCCCCCCCCCC | 28.52 | 28854356 | |
| 240 | Phosphorylation | PVHDSEESPSESRTE ECCCCCCCCCCCHHC | 29.67 | 19530675 | |
| 280 | N-linked_Glycosylation | DAGLTELNITAEEPP CCCCEEEEEECCCCC | 24.27 | - | |
| 299 | N-linked_Glycosylation | NDNIVLFNETHALPA CCEEEEECCCCCCCC | 49.44 | - | |
| 401 | N-linked_Glycosylation | IVPNILANQSVNIND ECCCCCCCCCCCCCC | 31.08 | - | |
| 407 | N-linked_Glycosylation | ANQSVNINDTATFHC CCCCCCCCCCCEEEE | 35.06 | - | |
| 433 | N-linked_Glycosylation | WVRINKINGSYSYYN EEEEEECCCCEECCC | 34.66 | - | |
| 440 | N-linked_Glycosylation | NGSYSYYNNSAEEYM CCCEECCCCCCCCEE | 27.96 | - | |
| 449 | N-linked_Glycosylation | SAEEYMFNYTEMDTF CCCCEEEEEEECCCC | 26.70 | - | |
| 474 | N-linked_Glycosylation | ESTLTIFNVSLDDQG CCEEEEEEEECCCCC | 20.72 | - | |
| 497 | N-linked_Glycosylation | SLGMSMANATLTVNE CCCCCCCCCEEEHHC | 25.47 | - | |
| 586 | Phosphorylation | MNEDNENSDDEPSPY CCCCCCCCCCCCCCC | 40.01 | 19530675 | |
| 744 | Phosphorylation | KEEKAKKSSQELTDY HHHHHHHHHHHHHHH | 36.23 | 30078680 | |
| 745 | Phosphorylation | EEKAKKSSQELTDYL HHHHHHHHHHHHHHH | 36.23 | 30078680 | |
| 827 | Phosphorylation | RDVHCNDYYRKRGNG CCCCCHHHHHHCCCC | 7.38 | 27067626 | |
| 828 | Phosphorylation | DVHCNDYYRKRGNGR CCCCHHHHHHCCCCC | 16.72 | 27067626 | |
| 1046 (in isoform 4) | Phosphorylation | - | 27067626 | ||
| 1046 (in isoform 3) | Phosphorylation | - | 27067626 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of EGL15_CAEEL !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of EGL15_CAEEL !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of EGL15_CAEEL !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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