PCF11_CAEEL - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: PCF11_CAEEL
• UniProt AC: Q09345
• Protein Name: Polyadenylation and cleavage factor homolog 11
• Gene Name: pcf-11
• Organism: Caenorhabditis elegans.
• Sequence Length: 823
• Protein Sequence: MESVESAARDYRETLAELRNNNKTQINLLTILADDFKKAAPQIVEVIERHLTTCSPSQKLLVMYVCDSILKNVKKPNDYDALFARKIVSMFEHAFRQGDERIRTSLYRIRVTWASTTLFMPSKLYELDMKINKLDPNWPISNPQTGRALRDDPQVMAPSQSRPAGNATSPAASTSTNRVFVNPKFIGSSTPGAASASKTVVEKTKSPGTVNKEKQVKKEPKQDPLDKLLPSSSASKTSSSPAGLKRKSAPSEHPNAPIRKKPQQPPKPQTAIDEDLRSISLTKKPPVPSAQDQDFRPKTLKPTSVIGSHAFAPVAAPIRPMIPVPPPVSVAPFVPAPPLSSAPPFQHPQQHHPQLPPPPVHQGMGRGYHHNSPPQDPAPIVPVQAPPPQQHLPAPENVYSSEQPKLDVPANNRIFVDGKAYEVMFVDDTAVIERGGAPHRIYFAGPPRNLVIDGIPHLLQFDTPTQIDILGSKHMVKFGAPSRELYIGGHPFKGQFGGPPIIATINGRRHEIRLTGSAPEVRIEPEPAYHLTHFLHKMREEKKIEIASEKPEKKEDWLSYLKNLRTRNILPAPARSPSSPRNQTPPPANLPIPGMNNAGQRGGYHNRHQPQQNARWGGANKQQNIPPPPSDPSPIGSGVEKRSAPPAAITDFNIRLLQIRYDSVVDALITKRADACKFCGMRLDDSQGKSKEWQDHMDWHVKQNLARHGSNNSAAVPYRQWYPSTSTWLTPRASDETNEQEADKPEEPLPGVASSGVKTKECSVCGEKFDEYYDDDEETWRLRDTVNVHGKIVHSACASDAARSLDNSSFFNDSDIKKEEPFD

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
169	Phosphorylation	RPAGNATSPAASTST CCCCCCCCCCCCCCC	15.33	21082442
237	Phosphorylation	PSSSASKTSSSPAGL CCCCCCCCCCCCCCC	31.20	30078680
238	Phosphorylation	SSSASKTSSSPAGLK CCCCCCCCCCCCCCC	32.33	30078680
239	Phosphorylation	SSASKTSSSPAGLKR CCCCCCCCCCCCCCC	45.64	30078680
240	Phosphorylation	SASKTSSSPAGLKRK CCCCCCCCCCCCCCC	20.66	30078680
576	Phosphorylation	ILPAPARSPSSPRNQ CCCCCCCCCCCCCCC	31.10	28854356
578	Phosphorylation	PAPARSPSSPRNQTP CCCCCCCCCCCCCCC	54.97	19530675
579	Phosphorylation	APARSPSSPRNQTPP CCCCCCCCCCCCCCC	31.12	19530675
584	Phosphorylation	PSSPRNQTPPPANLP CCCCCCCCCCCCCCC	41.11	28854356

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of PCF11_CAEEL !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of PCF11_CAEEL !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of PCF11_CAEEL !!

Protein-Protein Interaction

Oops, there are no PPI records of PCF11_CAEEL !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.