dbPTM

PROS1_CAEEL - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	PROS1_CAEEL
UniProt AC	P34522
Protein Name	Homeobox protein prospero homolog 1 {ECO:0000312\|WormBase:K12H4.1}
Gene Name	pros-1 {ECO:0000312\|WormBase:K12H4.1}
Organism	Caenorhabditis elegans.
Sequence Length	594
Subcellular Localization	Nucleus .
Protein Description	Transcription factor involved in developmental processes (By similarity). Controls the transcription of genes required for excretory canal formation. [PubMed: 23334499]
Protein Sequence	MSSGLPSIAATAQPSANGFSFNNGFPPFGIYYSQLPPVNSNGSTPNSSNRFKVKRHRQRVDAGEPRNTYQGASTSVSSNSSSSSSTSNTNSTPSSSSTSSKKSTEGMTETETMTASIEQEKVIQNEESEAGKDGMEEHDDGMNDFEIIDDTNDEVEESEERESPESNSSSASKRKSFQPQKIGEELGIEFGDETEQINVTVGGTEEAEETTDEAEGRELSALQAQLQNGHIAEQQRRFYAAFLDQQRKQVAAAQILHNGKINIERLVSSVKGDLVTNFMKDLEKVIRDWAADEVLKQEAAAPPQIPQPPPQFHPIFPANPLFHMAPPHHPVAGGGIFPPNFNAFNAFNALRRNLQDVDTSSEMKKKRTKVEIKKEDAMSSRASPLSASASPPLSRFFPAPTMVGHYGGMNFGDREDSPTNSDELSECGYEGGGSSSMLTPMHLRKAKLMFFYTRYPNSNLLKSYFPDIRFNKNNTAQLVKWFSNFREFYYNQMEKFARQALAEGITDRNDIFVSKDSELFKVLNTHYNRNNHIKAPDRLVFVVQETLREFHDAIKQGKDIEPSWKKTIYKVINRLEDQIPDFFKEPNFLERLET

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
388	Phosphorylation	RASPLSASASPPLSR CCCCCCCCCCCCHHH		28854356
390	Phosphorylation	SPLSASASPPLSRFF CCCCCCCCCCHHHCC		28854356

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of PROS1_CAEEL !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of PROS1_CAEEL !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of PROS1_CAEEL !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of PROS1_CAEEL !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of PROS1_CAEEL

Related Literatures of Post-Translational Modification