dbPTM

FUMH_CAEEL - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	FUMH_CAEEL
UniProt AC	O17214
Protein Name	Probable fumarate hydratase, mitochondrial
Gene Name	fum-1
Organism	Caenorhabditis elegans.
Sequence Length	501
Subcellular Localization	Mitochondrion.
Protein Description
Protein Sequence	MSAVSMLQGEMLARGGAVIARGASLATARNFSRTTVPMAKIRKERDTFGELEVPADKYYGAQTARSQMNFKIGGPEERMPIPVIHAFGILKKAAALVNTEFGLDKKLADAISQAADEVVDGKLDEHFPLVTWQTGSGTQSNMNVNEVISNRAIEILGGELGSKKPVHPNDHVNMSQSSNDTFPTAMHIAVGREVNSRLLPALKKLRTALHNKAEEFKDIIKIGRTHTQDAVPLTLGQEFSAYVTQLDNSIARVESTLPRLYQLAAGGTAVGTGLNTRKGFAEKVAATVSELTGLPFVTAPNKFEALAAHDALVEVHGALNTVAVSFMKIGNDIRFLGSGPRCGLGELSLPENEPGSSIMPGKVNPTQCEAITMVAAQVMGNQVAVSVGGSNGHFELNVFKPLIVRNVLQSTRLLADSAVSFTDHCVDGIVANKDNIAKIMRESLMLVTALNPHIGYDNAAKIAKTAHKNGTTLVQEAVKLGILTEEQFAQWVKPENMLGPK

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
47	Phosphorylation	KIRKERDTFGELEVP HHHCCCCCCCCCCCC	39.50	26392051
162	Phosphorylation	ILGGELGSKKPVHPN HHCCCCCCCCCCCCC	50.56	28854356

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of FUMH_CAEEL !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of FUMH_CAEEL !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of FUMH_CAEEL !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of FUMH_CAEEL !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of FUMH_CAEEL

Related Literatures of Post-Translational Modification