DHX16_CAEEL - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: DHX16_CAEEL
• UniProt AC: O45244
• Protein Name: Probable pre-mRNA-splicing factor ATP-dependent RNA helicase mog-4
• Gene Name: mog-4
• Organism: Caenorhabditis elegans.
• Sequence Length: 1008
• Subcellular Localization: Nucleus .
• Protein Description: ATP-binding RNA helicase involved in pre-mRNA splicing (Probable). Operates during embryogenesis..
• Protein Sequence: MSVEQFINDQLHSIVGISDRSICQYVHALAKKAKSAPDLVEKLRDAGDFPISPAIQSFADQLMSRMPRQATSARQRGPTTAELAEQELNRLNRAVGVLEDYSASSTKTKNVRKRKESSSEDDEAPIKASKPGKSVKPSKSDDSESDIEAMEAKLDADIAERDALAARINKKEKDKTRNVMEKKRDDNKDKEGSSMDKLREESRRQYLKKRKVDKLEELEAIVHDDQTLFAREKLTKREKADMEYRKKVLEYTKAHGKAGDVMKMKRYHLPDASTKQIPSQYVEDDEEDFRPGGDGAKWEEEQLMASMLHLGAKDAKRKEQEFELLLDEKVDFIQALQMPGTNEEVVETEAEKKKMSIEETRKSLPVYAFRDAFIEAVKEHQVLIIEGETGSGKTTQLPQYLYEAGFCEGGKRIGCTQPRRVAAMSVAARVADEVGCKLGTQVGYSIRFEDCTSEKTVLKYMTDGMLLREFLNEPDLASYSVMMIDEAHERTLHTDILFGLVKDIARFRKDLKLLISSATLDAEKFSSFFDDAPIFRIPGRRFPVDIYYTQAPEADYVDAAIVTIMQIHLTQPLPGDILVFLTGQEEIETVQEALMERSKALGSKIKELIPLPVYANLPSDLQAKIFEPTPKDARKVVLATNIAETSVTIDGINYVIDPGFSKQNSFDARSGVEHLHVVTISKAAANQRAGRAGRTGPGKCFRLYTAWAYKHELEEQPIPEIQRTNLGNVVLMLKSLGIHDLVHFDFLDPPPQETLVIALEQLYALGALNHRGELTKLGRRMAEFPCDPCMSKMIIASEKYECSEEIVTIAAMLSCNAAVFYRPKAQVIHADSARKGFWSPAGDHITLMNVYNKWQESSFSQRWCVENYVQHRTMKRARDVRDQLVGLLERVEIETKSSTDTIKIRKAITAGYFYNVSKLDNTGHYKTVKHKHTTHPHPNSCLFEETPRWVVYFELVFTSKEFMREMSEIESGWLLEVAPHYYKGRELEDATNKKMPKNKGKSGKDLER

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
117	Phosphorylation	NVRKRKESSSEDDEA CCHHCCCCCCCCCCC	42.05	21082442
118	Phosphorylation	VRKRKESSSEDDEAP CHHCCCCCCCCCCCC	38.55	21082442
119	Phosphorylation	RKRKESSSEDDEAPI HHCCCCCCCCCCCCC	55.08	21082442
138	Phosphorylation	PGKSVKPSKSDDSES CCCCCCCCCCCCCHH	38.79	21082442
140	Phosphorylation	KSVKPSKSDDSESDI CCCCCCCCCCCHHHH	51.49	21082442
143	Phosphorylation	KPSKSDDSESDIEAM CCCCCCCCHHHHHHH	43.95	21082442
145	Phosphorylation	SKSDDSESDIEAMEA CCCCCCHHHHHHHHH	48.08	21082442

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of DHX16_CAEEL !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of DHX16_CAEEL !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of DHX16_CAEEL !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
MEP1_CAEEL	mep-1	physical	12088146
MOG1_CAEEL	mog-1	physical	12088146

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.