dbPTM

MOM2_CAEEL - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	MOM2_CAEEL
UniProt AC	Q10459
Protein Name	Protein mom-2
Gene Name	mom-2
Organism	Caenorhabditis elegans.
Sequence Length	362
Subcellular Localization	Secreted, extracellular space, extracellular matrix.
Protein Description	Ligand for members of the frizzled family of seven transmembrane receptors. Required in embryonic development for endoderm specification and the correct positioning and orientation of the mitotic spindles and division planes in blastomere cells. [PubMed: 9288750]
Protein Sequence	MHINTPVLLAIIYFLVFAPKSADAWWLLSKTDTSSANSGSSPILCKNVPGLTPQQKRMCHENPNIIKYLISGLRSALHTCEYTFQREAWNCTLTLPGVGTSPLQIASRESAYVYAISAAGVSHSLARACSKGLIDDCGCGETPQGSGSVAVSQASSRSSSDFVWAGCSDNVKFGNTFGRKFVDQYDRQHATEPRSQMNLHNNRVGRRLLVNAMNKECKCHGVSGSCVTKTCWKVMPKFDEFASRLHQKYQLAKLVTNNDQKLTVRSSPSAGSSGRSERFARNMDASSKQMRNELIYLDASPNYCAIDVKDRECGENCPNICCGRGWRTTREIVDEPCHCQFVWCCEVKCKTCKKLVERNYCL

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
90	N-linked_Glycosylation	TFQREAWNCTLTLPG EECCCCCCEEEECCC	18.88	-
223	O-palmitoleoylation	ECKCHGVSGSCVTKT CCCCCCCCCCCCCHH	29.58	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of MOM2_CAEEL !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of MOM2_CAEEL !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of MOM2_CAEEL !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
NLK_CAEEL	lit-1	genetic	10380924
EFN4_CAEEL	efn-4	genetic	16845399
UNC22_CAEEL	unc-22	genetic	16845399
YM2A_CAEEL	zfp-1	genetic	16845399
YM2B_CAEEL	zfp-1	genetic	16845399
MUT7_CAEEL	mut-7	genetic	11904378
YM2A_CAEEL	zfp-1	genetic	11904378
YM2B_CAEEL	zfp-1	genetic	11904378
MES3_CAEEL	mes-3	genetic	11904378
MES4_CAEEL	mes-4	genetic	11904378
MES6_CAEEL	mes-6	genetic	11904378
POP1_CAEEL	pop-1	genetic	19084000

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of MOM2_CAEEL

Related Literatures of Post-Translational Modification