UNC22_CAEEL - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: UNC22_CAEEL
• UniProt AC: Q23551
• Protein Name: Twitchin {ECO:0000303|PubMed:7190524}
• Gene Name: unc-22 {ECO:0000312|WormBase:ZK617.1b}
• Organism: Caenorhabditis elegans.
• Sequence Length: 7158
• Subcellular Localization: Cytoplasm, myofibril, sarcomere . Cytoplasm, myofibril, sarcomere, A band . Expressed at the outer edge of A-bands.
• Protein Description: Regulator of muscle contraction and relaxation. Senses mechanical strain that occurs during muscle activity by unfolding in clearly resolvable steps at differing forces. [PubMed: 18390597]
• Protein Sequence: MVGAPRFTQKPSIQQTPTGDLLMECHLEADPQPTIAWQHSGNLLEPSGRVVQTLTPLGGSLYKATLVIKEPNAGDGGAYKCTARNQLGESNANINLNFAGAGGDEAKSRGPSFVGKPRIIPKDGGALIVMECKVKSASTPVAKWMKDGVPLSMGGLYHAIFSDLGDQTYLCQLEIRGPSSSDAGQYRCNIRNDQGETNANLALNFEEPDPSERQERKRSTASPRPSSRGPGSRPSSPKKSMKSREGTPKRTLKPREGSPSKKLRSRTSTPVNEEVSQSESRRSSRTDKMEVDQVSGASKRKPDGLPPPGGDEKKLRAGSPSTRKSPSRKSASPTPSRKGSSAGGAASGTTGASASATSATSGGSASSDASRDKYTRPPIVLEASRSQTGRIGGSVVLEVQWQCHSSTIIEWYRDGTLVRNSSEYSQSFNGSIAKLQVNKLTEEKSGLYKCHAKCDYGEGQSSAMVKIEQSDVEEELMKHRKDAEDEYQKEEQKSQTLQAETKKRVARRSKSKSKSPAPQAKKSTTSESGRQEASEVEHKRSSSVRPDPDEESQLDEIPSSGLTIPEERRRELLGQVGESDDEVSESISELPSFAGGKPRRKTDSPPKQDDMFSRDTLLRKTTTSTKNESSTVEEKTKLRKTVKKVDGELDFKAMVKLKKVKKEEGGTTEKSGFPLDHADSTSSVLSQESRSRRGSNAPFAKDGLPEQPANPFAQLKKVKSGAGGLEKSDSMASLKKLDLKKGKIDDNSDGAFKVQLKKVVKKEVKESTISVKEKNGTESGIKTEFKMEKRERTTLQKYEKTDSDGSKKEDKPKKVSIAPVSTNKSSDDEPSTPRHHKEVEEKSTSEELKAKVAGRQVGQKRNGAQKPEEPKNLLSQIQLKKVTKKAHDDTNELEGIKLKKVTTVPKHVADDDSQSESESRRGSVFGELRRGSRAPRDSADNSRRDSIRRSSIDMRRESVQEILEKTSTPLVPSGASGSAPKIVEVPENVTVVENETAILTCKVSGSPAPTFRWFKGSREVISGGRFKHITDGKEHTVALALLKCRSQDEGPYTLTIENVHGTDSADVKLLVTSDNGLDFRAMLKHRESQAGFQKDGEGGGAGGGGGEKKPMTEAERRQSLFPGKKVEKWDIPLPEKTVQQQVDKICEWKCTYSRPNAKIRWYKDRKEIFSGGLKYKIVIEKNVCTLIINNPEVDDTGKYTCEANGVPTHAQLTVLEPPMKYSFLNPLPNTQEIYRTKQAVLTCKVNTPRAPLVWYRGSKAIQEGDPRFIIEKDAVGRCTLTIKEVEEDDQAEWTARITQDVFSKVQVYVEEPRHTFVVPMKSQKVNESDLATLETDVNDKDAEVVWWHDGKRIDIDGVKFKVESSNRKRRLIINGARIEDHGEYKCTTKDDRTMAQLIVDAKNKFIVALKDTEVIEKDDVTLMCQTKDTKTPGIWFRNGKQISSMPGGKFETQSRNGTHTLKIGKIEMNEADVYEIDQAGLRGSCNVTVLEAEKRPILNWKPKKIEAKAGEPCVVKVPFQIKGTRRGDPKAQILKNGKPIDEEMRKLVEVIIKDDVAEIVFKNPQLADTGKWALELGNSAGTALAPFELFVKDKPKPPKGPLETKNVTAEGLDLVWGTPDPDEGAPVKAYIIEMQEGRSGNWAKVGETKGTDFKVKDLKEHGEYKFRVKALNECGLSDPLTGESVLAKNPYGVPGKPKNMDAIDVDKDHCTLAWEPPEEDGGAPITGYIIERREKSEKDWHQVGQTKPDCCELTDKKVVEDKEYLYRVKAVNKAGPGDPCDHGKPIKMKAKKASPEFTGGGIKDLRLKVGETIKYDVPISGEPLPECLWVVNGKPLKAVGRVKMSSERGKHIMKIENAVRADSGKFTITLKNSSGSCDSTATVTVVGRPTPPKGPLDIADVCADGATLSWNPPDDDGGDPLTGYIVEAQDMDNKGKYIEVGKVDPNTTTLKVNGLRNKGNYKFRVKAVNNEGESEPLSADQYTQIKDPWDEPGKPGRPEITDFDADRIDIAWEPPHKDGGAPIEEYIVEVRDPDTKEWKEVKRVPDTNASISGLKEGKEYQFRVRAVNKAGPGQPSEPSEKQLAKPKFIPAWLKHDNLKSITVKAGATVRWEVKIGGEPIPEVKWFKGNQQLENGIQLTIDTRKNEHTILCIPSAMRSDVGEYRLTVKNSHGADEEKANLTVLDRPSKPNGPLEVSDVFEDNLNLSWKPPDDDGGEPIEYYEVEKLDTATGRWVPCAKVKDTKAHIDGLKKGQTYQFRVKAVNKEGASDALSTDKDTKAKNPYDEPGKTGTPDVVDWDADRVSLEWEPPKSDGGAPITQYVIEKKGKHGRDWQECGKVSGDQTNAEILGLKEGEEYQFRVKAVNKAGPGEASDPSRKVVAKPRNLKPWIDREAMKTITIKVGNDVEFDVPVRGEPPPKKEWIFNEKPVDDQKIRIESEDYKTRFVLRGATRKHAGLYTLTATNASGSDKHSVEVIVLGKPSSPLGPLEVSNVYEDRADLEWKVPEDDGGAPIDHYEIEKMDLATGRWVPCGRSETTKTTVPNLQPGHEYKFRVRAVNKEGESDPLTTNTAILAKNPYEVPGKVDKPELVDWDKDHVDLAWNAPDDGGAPIEAFVIEKKDKNGRWEEALVVPGDQKTATVPNLKEGEEYQFRISARNKAGTGDPSDPSDRVVAKPRNLAPRIHREDLSDTTVKVGATLKFIVHIDGEPAPDVTWSFNGKGIGESKAQIENEPYISRFALPKALRKQSGKYTITATNINGTDSVTINIKVKSKPTKPKGPIEVTDVFEDRATLDWKPPEDDGGEPIEFYEIEKMNTKDGIWVPCGRSGDTHFTVDSLNKGDHYKFRVKAVNSEGPSDPLETETDILAKNPFDRPDRPGRPEPTDWDSDHVDLKWDPPLSDGGAPIEEYQIEKRTKYGRWEPAITVPGGQTTATVPDLTPNEEYEFRVVAVNKGGPSDPSDASKAVIAKPRNLKPHIDRDALKNLTIKAGQSISFDVPVSGEPAPTVTWHWPDNREIRNGGRVKLDNPEYQSKLVVKQMERGDSGTFTIKAVNANGEDEATVKINVIDKPTSPNGPLDVSDVHGDHVTLNWRAPDDDGGIPIENYVIEKYDTASGRWVPAAKVAGDKTTAVVDGLIPGHEYKFRVAAVNAEGESDPLETFGTTLAKDPFDKPGKTNAPEITDWDKDHVDLEWKPPANDGGAPIEEYVVEMKDEFSPFWNDVAHVPAGQTNATVGNLKEGSKYEFRIRAKNKAGLGDPSDSASAVAKARNVPPVIDRNSIQEIKVKAGQDFSLNIPVSGEPTPTITWTFEGTPVESDDRMKLNNEDGKTKFHVKRALRSDTGTYIIKAENENGTDTAEVKVTVLDHPSSPRGPLDVTNIVKDGCDLAWKEPEDDGGAEISHYVIEKQDAATGRWTACGESKDTNFHVDDLTQGHEYKFRVKAVNRHGDSDPLEAREAIIAKDPFDRADKPGTPEIVDWDKDHADLKWTPPADDGGAPIEGYLVEMRTPSGDWVPAVTVGAGELTATVDGLKPGQTYQFRVKALNKAGESTPSDPSRTMVAKPRHLAPKINRDMFVAQRVKAGQTLNFDVNVEGEPAPKIEWFLNGSPLSSGGNTHIDNNTDNNTKLTTKSTARADSGKYKIVATNESGKDEHEVDVNILDIPGAPEGPLRHKDITKESVVLKWDEPLDDGGSPITNYVVEKQEDGGRWVPCGETSDTSLKVNKLSEGHEYKFRVKAVNRQGTSAPLTSDHAIVAKNPFDEPDAPTDVTPVDWDKDHVDLEWKPPANDGGAPIDAYIVEKKDKFGDWVECARVDGKTTKATADNLTPGETYQFRVKAVNKAGPGKPSDPTGNVVAKPRRMAPKLNLAGLLDLRIKAGTPIKLDIAFEGEPAPVAKWKANDATIDTGARADVTNTPTSSAIHIFSAVRGDTGVYKIIVENEHGKDTAQCNVTVLDVPGTPEGPLKIDEIHKEGCTLNWKPPTDNGGTDVLHYIVEKMDTSRGTWQEVGTFPDCTAKVNKLVPGKEYAFRVKAVNLQGESKPLEAEEPIIAKNQFDVPDPVDKPEVTDWDKDRIDIKWNPTANNGGAPVTGYIVEKKEKGSAIWTEAGKTPGTTFSADNLKPGVEYEFRVIAVNAAGPSDPSDPTDPQITKARYLKPKILTASRKIKIKAGFTHNLEVDFIGAPDPTATWTVGDSGAALAPELLVDAKSSTTSIFFPSAKRADSGNYKLKVKNELGEDEAIFEVIVQDRPSAPEGPLEVSDVTKDSCVLNWKPPKDDGGAEISNYVVEKRDTKTNTWVPVSAFVTGTSITVPKLTEGHEYEFRVMAENTFGRSDSLNTDEPVLAKDPFGTPGKPGRPEIVDTDNDHIDIKWDPPRDNGGSPVDHYDIERKDAKTGRWIKVNTSPVQGTAFSDTRVQKGHTYEYRVVAVNKAGPGQPSDSSAAATAKPMHEAPKFDLDLDGKEFRVKAGEPLVITIPFTASPQPDISWTKEGGKPLAGVETTDSQTKLVIPSTRRSDSGPVKIKAVNPYGEAEANIKITVIDKPGAPENITYPAVSRHTCTLNWDAPKDDGGAEIAGYKIEYQEVGSQIWDKVPGLISGTAYTVRGLEHGQQYRFRIRAENAVGLSDYCQGVPVVIKDPFDPPGAPSTPEITGYDTNQVSLAWNPPRDDGGSPILGYVVERFEKRGGGDWAPVKMPMVKGTECIVPGLHENETYQFRVRAVNAAGHGEPSNGSEPVTCRPYVEKPGAPDAPRVGKITKNSAELTWNRPLRDGGAPIDGYIVEKKKLGDNDWTRCNDKPVRDTAFEVKNLGEKEEYEFRVIAVNSAGEGEPSKPSDLVLIEEQPGRPIFDINNLKDITVRAGETIQIRIPYAGGNPKPIIDLFNGNSPIFENERTVVDVNPGEIVITTTGSKRSDAGPYKISATNKYGKDTCKLNVFVLDAPGKPTGPIRATDIQADAMTLSWRPPKDNGGDAITNYVVEKRTPGGDWVTVGHPVGTTLRVRNLDANTPYEFRVRAENQYGVGEPLETDDAIVAKNPFDTPGAPGQPEAVETSEEAITLQWTRPTSDGGAPIQGYVIEKREVGSTEWTKAAFGNILDTKHRVTGLTPKKTYEFRVAAYNAAGQGEYSVNSVPITADNAPTRPKINMGMLTRDILAYAGERAKILVPFAASPAPKVTFSKGENKISPTDPRVKVEYSDFLATLTIEKSELTDGGLYFVELENSQGSDSASIRLKVVDKPASPQHIRVEDIAPDCCTLYWMPPSSDGGSPITNYIVEKLDLRHSDGKWEKVSSFVRNLNYTVGGLIKDNRYRFRVRAETQYGVSEPCELADVVVAKYQFEVPNQPEAPTVRDKDSTWAELEWDPPRDGGSKIIGYQVQYRDTSSGRWINAKMDLSEQCHARVTGLRQNGEFEFRIIAKNAAGFSKPSPPSERCQLKSRFGPPGPPIHVGAKSIGRNHCTITWMAPLEDGGSKITGYNVEIREYGSTLWTVASDYNVREPEFTVDKLREFNDYEFRVVAINAAGKGIPSLPSGPIKIQESGGSRPQIVVKPEDTAQPYNRRAVFTCEAVGRPEPTARWLRNGRELPESSRYRFEASDGVYKFTIKEVWDIDAGEYTVEVSNPYGSDTATANLVVQAPPVIEKDVPNTILPSGDLVRLKIYFSGTAPFRHSLVLNREEIDMDHPTIRIVEFDDHILITIPALSVREAGRYEYTVSNDSGEATTGFWLNVTGLPEAPQGPLHISNIGPSTATLSWRPPVTDGGSKITSYVVEKRDLSKDEWVTVTSNVKDMNYIVTGLFENHEYEFRVSAQNENGIGAPLVSEHPIIARLPFDPPTSPLNLEIVQVGGDYVTLSWQRPLSDGGGRLRGYIVEKQEEEHDEWFRCNQNPSPPNNYNVPNLIDGRKYRYRVFAVNDAGLSDLAELDQTLFQASGSGEGPKIVSPLSDLNEEVGRCVTFECEISGSPRPEYRWFKGCKELVDTSKYTLINKGDKQVLIINDLTSDDADEYTCRATNSSGTRSTRANLRIKTKPRVFIPPKYHGGYEAQKGETIELKIPYKAYPQGEARWTKDGEKIENNSKFSITTDDKFATLRISNASREDYGEYRVVVENSVGSDSGTVNVTVADVPEPPRFPIIENILDEAVILSWKPPALDGGSLVTNYTIEKREAMGGSWSPCAKSRYTYTTIEGLRAGKQYEFRIIAENKHGQSKPCEPTAPVLIPGDERKRRRGYDVDEQGKIVRGKGTVSSNYDNYVFDIWKQYYPQPVEIKHDHVLDHYDIHEELGTGAFGVVHRVTERATGNNFAAKFVMTPHESDKETVRKEIQTMSVLRHPTLVNLHDAFEDDNEMVMIYEFMSGGELFEKVADEHNKMSEDEAVEYMRQVCKGLCHMHENNYVHLDLKPENIMFTTKRSNELKLIDFGLTAHLDPKQSVKVTTGTAEFAAPEVAEGKPVGYYTDMWSVGVLSYILLSGLSPFGGENDDETLRNVKSCDWNMDDSAFSGISEDGKDFIRKLLLADPNTRMTIHQALEHPWLTPGNAPGRDSQIPSSRYTKIRDSIKTKYDAWPEPLPPLGRISNYSSLRKHRPQEYSIRDAFWDRSEAQPRFIVKPYGTEVGEGQSANFYCRVIASSPPVVTWHKDDRELKQSVKYMKRYNGNDYGLTINRVKGDDKGEYTVRAKNSYGTKEEIVFLNVTRHSEPLKFEPLEPMKKAPSPPRVEEFKERRSAPFFTFHLRNRLIQKNHQCKLTCSLQGNPNPTIEWMKDGHPVDEDRVQVSFRSGVCSLEIFNARVDDAGTYTVTATNDLGVDVSECVLTVQTKGGEPIPRVSSFRPRRAYDTLSTGTDVERSHSYADMRRRSLIRDVSPDVRSAADDLKTKITNELPSFTAQLSDSETEVGGSAEFSAAVSGQPEPLIEWLHNGERISESDSRFRASYVAGKATLRISDAKKSDEGQYLCRASNSAGQEQTRATLTVKGDQPLLNGHAGQAVESELRVTKHLGGEIVNNGESVTFEARVQGTPEEVLWMRNGQELTNGDKTSISQDGETLSFTINSADASDAGHYQLEVRSKGTNLVSVASLVVVGEKADPPVTRLPSSVSAPLGGSTAFTIEFENVEGLTVQWFRGSEKIEKNERVKSVKTGNTFKLDIKNVEQDDDGIYVAKVVKEKKAIAKYAAALLLV

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
215 (in isoform 5)	Phosphorylation	-	67.40	28854356
216 (in isoform 5)	Phosphorylation	-	31.20	28854356
219	Phosphorylation	ERQERKRSTASPRPS HHHHHHHHCCCCCCC	31.21	19060867
220	Phosphorylation	RQERKRSTASPRPSS HHHHHHHCCCCCCCC	34.88	21082442
222	Phosphorylation	ERKRSTASPRPSSRG HHHHHCCCCCCCCCC	22.87	19060867
226	Phosphorylation	STASPRPSSRGPGSR HCCCCCCCCCCCCCC	33.67	19530675
227	Phosphorylation	TASPRPSSRGPGSRP CCCCCCCCCCCCCCC	43.89	19060867
227 (in isoform 5)	Phosphorylation	-	43.89	28854356
228 (in isoform 5)	Phosphorylation	-	60.71	28854356
232	Phosphorylation	PSSRGPGSRPSSPKK CCCCCCCCCCCCCCC	44.12	19060867
235	Phosphorylation	RGPGSRPSSPKKSMK CCCCCCCCCCCCCCC	59.15	18806794
235 (in isoform 5)	Phosphorylation	-	59.15	28854356
236	Phosphorylation	GPGSRPSSPKKSMKS CCCCCCCCCCCCCCC	43.34	19060867
258	Phosphorylation	TLKPREGSPSKKLRS CCCCCCCCCCCCCCC	22.65	30078680
265	Phosphorylation	SPSKKLRSRTSTPVN CCCCCCCCCCCCCCC	50.80	28854356
267	Phosphorylation	SKKLRSRTSTPVNEE CCCCCCCCCCCCCHH	37.89	28854356
268	Phosphorylation	KKLRSRTSTPVNEEV CCCCCCCCCCCCHHH	29.60	19060867
269	Phosphorylation	KLRSRTSTPVNEEVS CCCCCCCCCCCHHHC	30.55	28854356
276	Phosphorylation	TPVNEEVSQSESRRS CCCCHHHCHHHHHHC	31.13	18806794
278	Phosphorylation	VNEEVSQSESRRSSR CCHHHCHHHHHHCCC	29.99	21082442
280	Phosphorylation	EEVSQSESRRSSRTD HHHCHHHHHHCCCCC	37.94	19060867
283	Phosphorylation	SQSESRRSSRTDKME CHHHHHHCCCCCCHH	24.06	21082442
284	Phosphorylation	QSESRRSSRTDKMEV HHHHHHCCCCCCHHH	37.07	21082442
319	Phosphorylation	EKKLRAGSPSTRKSP HHCCCCCCCCCCCCC	18.07	28854356
321	Phosphorylation	KLRAGSPSTRKSPSR CCCCCCCCCCCCCCC	42.41	30078680
325	Phosphorylation	GSPSTRKSPSRKSAS CCCCCCCCCCCCCCC	25.47	21082442
330	Phosphorylation	RKSPSRKSASPTPSR CCCCCCCCCCCCCCC	32.63	30078680
332	Phosphorylation	SPSRKSASPTPSRKG CCCCCCCCCCCCCCC	36.08	30078680
334	Phosphorylation	SRKSASPTPSRKGSS CCCCCCCCCCCCCCC	31.25	19060867
336	Phosphorylation	KSASPTPSRKGSSAG CCCCCCCCCCCCCCC	49.45	19530675
340	Phosphorylation	PTPSRKGSSAGGAAS CCCCCCCCCCCCCCC	21.76	19060867
341	Phosphorylation	TPSRKGSSAGGAASG CCCCCCCCCCCCCCC	39.33	19060867
347	Phosphorylation	SSAGGAASGTTGASA CCCCCCCCCCCCCCC	35.82	21082442
349	Phosphorylation	AGGAASGTTGASASA CCCCCCCCCCCCCCC	21.40	19530675
350	Phosphorylation	GGAASGTTGASASAT CCCCCCCCCCCCCCC	33.99	19530675
353	Phosphorylation	ASGTTGASASATSAT CCCCCCCCCCCCCCC	24.89	19530675
355	Phosphorylation	GTTGASASATSATSG CCCCCCCCCCCCCCC	29.59	19530675
357	Phosphorylation	TGASASATSATSGGS CCCCCCCCCCCCCCC	19.19	19530675
470	Phosphorylation	AMVKIEQSDVEEELM EEEEEECCHHHHHHH	30.73	28854356
511	Phosphorylation	RVARRSKSKSKSPAP HHHHHHHCCCCCCCC	43.33	18806794
513	Phosphorylation	ARRSKSKSKSPAPQA HHHHHCCCCCCCCCC	45.52	30078680
515	Phosphorylation	RSKSKSKSPAPQAKK HHHCCCCCCCCCCCC	33.13	30078680
523	Phosphorylation	PAPQAKKSTTSESGR CCCCCCCCCCCHHHC	35.89	28854356
524	Phosphorylation	APQAKKSTTSESGRQ CCCCCCCCCCHHHCH	43.13	19060867
525	Phosphorylation	PQAKKSTTSESGRQE CCCCCCCCCHHHCHH	37.27	19060867
526	Phosphorylation	QAKKSTTSESGRQEA CCCCCCCCHHHCHHH	29.83	19060867
528	Phosphorylation	KKSTTSESGRQEASE CCCCCCHHHCHHHHH	38.76	30078680
534	Phosphorylation	ESGRQEASEVEHKRS HHHCHHHHHHCHHHC	41.23	30078680
541	Phosphorylation	SEVEHKRSSSVRPDP HHHCHHHCCCCCCCC	31.59	19060867
542	Phosphorylation	EVEHKRSSSVRPDPD HHCHHHCCCCCCCCC	36.56	19060867
543	Phosphorylation	VEHKRSSSVRPDPDE HCHHHCCCCCCCCCH	24.32	19060867
552	Phosphorylation	RPDPDEESQLDEIPS CCCCCHHHCCCCCCC	33.71	30078680
579	Phosphorylation	LLGQVGESDDEVSES HHHCCCCCCHHHHHH	44.42	28854356
584	Phosphorylation	GESDDEVSESISELP CCCCHHHHHHHHHCC	24.47	28854356
586	Phosphorylation	SDDEVSESISELPSF CCHHHHHHHHHCCCC	24.73	30078680
588	Phosphorylation	DEVSESISELPSFAG HHHHHHHHHCCCCCC	42.22	30078680
619 (in isoform 2)	Phosphorylation	-	37.07	28854356
620 (in isoform 2)	Phosphorylation	-	50.63	28854356
631 (in isoform 2)	Phosphorylation	-	41.01	28854356
632 (in isoform 2)	Phosphorylation	-	10.92	28854356
639 (in isoform 2)	Phosphorylation	-	33.87	28854356
671	Phosphorylation	EGGTTEKSGFPLDHA HCCCCCCCCCCCCCC	39.16	19530675
675 (in isoform 4)	Phosphorylation	-	7.62	19530675
680	Phosphorylation	FPLDHADSTSSVLSQ CCCCCCCCHHHHHCH	30.85	19530675
681	Phosphorylation	PLDHADSTSSVLSQE CCCCCCCHHHHHCHH	26.10	18806794
682	Phosphorylation	LDHADSTSSVLSQES CCCCCCHHHHHCHHH	23.54	19530675
683	Phosphorylation	DHADSTSSVLSQESR CCCCCHHHHHCHHHH	27.45	19530675
686	Phosphorylation	DSTSSVLSQESRSRR CCHHHHHCHHHHHCC	29.73	21082442
689	Phosphorylation	SSVLSQESRSRRGSN HHHHCHHHHHCCCCC	28.11	19530675
695	Phosphorylation	ESRSRRGSNAPFAKD HHHHCCCCCCCCCCC	28.18	30078680
720	Phosphorylation	AQLKKVKSGAGGLEK HHHCCCCCCCCCCCC	36.54	30078680
772 (in isoform 4)	Phosphorylation	-	57.06	28854356
773 (in isoform 4)	Phosphorylation	-	49.99	28854356
784 (in isoform 4)	Phosphorylation	-	37.96	28854356
785 (in isoform 4)	Phosphorylation	-	12.66	28854356
792 (in isoform 4)	Phosphorylation	-	36.72	28854356
816	Phosphorylation	EDKPKKVSIAPVSTN CCCCCCEEEEECCCC	23.16	19060867
821	Phosphorylation	KVSIAPVSTNKSSDD CEEEEECCCCCCCCC	25.79	30078680
822	Phosphorylation	VSIAPVSTNKSSDDE EEEEECCCCCCCCCC	47.07	30078680
825	Phosphorylation	APVSTNKSSDDEPST EECCCCCCCCCCCCC	40.86	28854356
826	Phosphorylation	PVSTNKSSDDEPSTP ECCCCCCCCCCCCCC	51.17	28854356
831	Phosphorylation	KSSDDEPSTPRHHKE CCCCCCCCCCCCHHH	49.34	21082442
832	Phosphorylation	SSDDEPSTPRHHKEV CCCCCCCCCCCHHHH	34.75	21082442
913	Phosphorylation	KHVADDDSQSESESR CCCCCCCCCCCCHHH	42.47	30078680
915	Phosphorylation	VADDDSQSESESRRG CCCCCCCCCCHHHHC	47.22	30078680
917	Phosphorylation	DDDSQSESESRRGSV CCCCCCCCHHHHCHH	46.23	30078680
923	Phosphorylation	ESESRRGSVFGELRR CCHHHHCHHHHHHCC	16.68	30078680
950	Phosphorylation	RRDSIRRSSIDMRRE CHHHHHHHHHHHHHH	23.07	19060867
951	Phosphorylation	RDSIRRSSIDMRRES HHHHHHHHHHHHHHH	22.31	22923814
958	Phosphorylation	SIDMRRESVQEILEK HHHHHHHHHHHHHHH	27.56	28854356
1006	Phosphorylation	LTCKVSGSPAPTFRW EEEEECCCCCCCEEE	15.47	28854356
1088	Phosphorylation	AMLKHRESQAGFQKD HHHHHHHHHCCCCCC	25.86	19060867
1119	Phosphorylation	TEAERRQSLFPGKKV CHHHHHHCCCCCCCC	30.11	30078680
1618	Phosphorylation	GLDLVWGTPDPDEGA CEEEEECCCCCCCCC	14.60	28854356
1794	Phosphorylation	KMKAKKASPEFTGGG CCCEEECCCCCCCCC	33.57	28854356
2050	Phosphorylation	RVPDTNASISGLKEG CCCCCCCCCCCCCCC	21.25	26392051
2291	Phosphorylation	DEPGKTGTPDVVDWD CCCCCCCCCCCCCCC	22.88	30078680
2850	Phosphorylation	FRVKAVNSEGPSDPL EEEEEECCCCCCCCC	37.01	28854356
2897	Phosphorylation	LKWDPPLSDGGAPIE CCCCCCCCCCCCCCC	39.73	30078680
3041	Phosphorylation	KQMERGDSGTFTIKA EECCCCCCCEEEEEE	42.42	28854356
3255	Phosphorylation	KAGLGDPSDSASAVA CCCCCCCCCCHHHHH	49.27	19530675
3257	Phosphorylation	GLGDPSDSASAVAKA CCCCCCCCHHHHHHH	28.58	19530675
3259	Phosphorylation	GDPSDSASAVAKARN CCCCCCHHHHHHHCC	27.51	19530675
3364	Phosphorylation	VTVLDHPSSPRGPLD EEEECCCCCCCCCCC	49.94	28854356
3365	Phosphorylation	TVLDHPSSPRGPLDV EEECCCCCCCCCCCH	24.06	28854356
3373	Phosphorylation	PRGPLDVTNIVKDGC CCCCCCHHHHCCCCC	20.92	19530675
3468	Phosphorylation	DRADKPGTPEIVDWD CCCCCCCCCCCCCCC	26.69	30078680
3713	Phosphorylation	PCGETSDTSLKVNKL ECCCCCCCCEEEEEC	35.41	30078680
3714	Phosphorylation	CGETSDTSLKVNKLS CCCCCCCCEEEEECC	31.05	30078680
3873	Phosphorylation	DLRIKAGTPIKLDIA HCEECCCCCEEEEEE	27.05	28854356
3909	Phosphorylation	ARADVTNTPTSSAIH CCCCCCCCCCCHHHH	20.69	28854356
3946	Phosphorylation	DTAQCNVTVLDVPGT CCEECCEEEEECCCC	11.02	30078680
3953	Phosphorylation	TVLDVPGTPEGPLKI EEEECCCCCCCCCCH	16.46	30078680
4326	Phosphorylation	AENTFGRSDSLNTDE EECCCCCCCCCCCCC	31.75	30078680
4328	Phosphorylation	NTFGRSDSLNTDEPV CCCCCCCCCCCCCCC	25.43	28854356
4493	Phosphorylation	KPLAGVETTDSQTKL EECCCEEECCCCCEE	33.23	19530675
4494	Phosphorylation	PLAGVETTDSQTKLV ECCCEEECCCCCEEE	21.83	19530675
4496	Phosphorylation	AGVETTDSQTKLVIP CCEEECCCCCEEECC	37.34	19530675
4498	Phosphorylation	VETTDSQTKLVIPST EEECCCCCEEECCCC	30.23	19530675
4664	Phosphorylation	PPRDDGGSPILGYVV CCCCCCCCCCHHHHH	17.81	30078680
4999	Phosphorylation	VRNLDANTPYEFRVR EEECCCCCCEEEEEE	29.03	30078680
5161	Phosphorylation	ILVPFAASPAPKVTF EEEEECCCCCCCEEE	20.40	28854356
5231	Phosphorylation	KVVDKPASPQHIRVE EEECCCCCCCCEEEE	33.35	28854356
5919	Phosphorylation	TLFQASGSGEGPKIV HHHHCCCCCCCCEEE	31.04	28854356
6418	Phosphorylation	PKQSVKVTTGTAEFA HHHCEEEEECCEEEE	17.50	30078680
6419	Phosphorylation	KQSVKVTTGTAEFAA HHCEEEEECCEEEEC	35.21	30078680
6571	Phosphorylation	RKHRPQEYSIRDAFW HHCCCCCCCHHHHCC	12.26	27067626
6675	Phosphorylation	EIVFLNVTRHSEPLK EEEEEEECCCCCCCC	22.91	28854356
6678	Phosphorylation	FLNVTRHSEPLKFEP EEEECCCCCCCCCCC	37.30	28854356
6694	Phosphorylation	EPMKKAPSPPRVEEF CCCCCCCCCCCHHHH	53.01	28854356
6809	Phosphorylation	EPIPRVSSFRPRRAY CCCCCCCCCCCCCHH	23.55	19530675
6828	Phosphorylation	TGTDVERSHSYADMR CCCCCHHCCCHHHHH	11.86	19530675
6830	Phosphorylation	TDVERSHSYADMRRR CCCHHCCCHHHHHHH	24.22	19060867
6838	Phosphorylation	YADMRRRSLIRDVSP HHHHHHHHHHHHCCH	26.74	30078680
6844	Phosphorylation	RSLIRDVSPDVRSAA HHHHHHCCHHHHHHH	21.48	28854356
6849	Phosphorylation	DVSPDVRSAADDLKT HCCHHHHHHHHHHHH	27.88	19530675

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of UNC22_CAEEL !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of UNC22_CAEEL !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of UNC22_CAEEL !!

Protein-Protein Interaction

Oops, there are no PPI records of UNC22_CAEEL !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.