LIN3_CAEEL - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: LIN3_CAEEL
• UniProt AC: Q03345
• Protein Name: Protein lin-3
• Gene Name: lin-3
• Organism: Caenorhabditis elegans.
• Sequence Length: 438
• Subcellular Localization: Membrane; Single-pass type I membrane protein.
• Protein Description: Probable ligand for tyrosine kinase receptor let-23. Essential for vulval induction, where it acts downstream of the synthetic multivulva (synMuv) class genes. [PubMed: 1641037]
• Protein Sequence: MRKMLLFCILLLFMPQFTVSESCLPSWFRQERSAPEQLQSAENAAENSGSVPPDTSRNSLETNEIGDAPSSTSTPETPTETTISEAGDDEKRTEEVAKELIEKEAEYEGEYEDEKVDEEVEEALKYNEDATQDATSTLKPAVRKEIEKLKEAKCKDYCHHNATCHVEVIFREDRVSAVVPSCHCPQGWEGTRCDRHYVQAFYAPINGRYNVRLSTMSSTAQLLVQQSSTSAIPAFAFLIVMLIMFITIVVYAYRRMSKRSDDMTYTMSHMCPPEAFNVLKTPNGRHIPVHQIPSCSYTIPTPGTVPPNISSTPGSRIPTRQQAIRNNEQARNNFFSILRSQGTIPSRSINDDDTPKHYKSVPRVEVSAINYSGHIDFSTVSYQSTESEVSKASVTCPPPAHTVINIELDSADTNFRSPSRSSGEQGSPATCEPMIRHT

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
161	N-linked_Glycosylation	CKDYCHHNATCHVEV CCCCCCCCCEEEEEE	17.18	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of LIN3_CAEEL !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of LIN3_CAEEL !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of LIN3_CAEEL !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.