dbPTM

LIAS_CAEEL - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	LIAS_CAEEL
UniProt AC	Q21452
Protein Name	Lipoyl synthase, mitochondrial {ECO:0000255\|HAMAP-Rule:MF_03123}
Gene Name	M01F1.3
Organism	Caenorhabditis elegans.
Sequence Length	354
Subcellular Localization	Mitochondrion .
Protein Description	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives..
Protein Sequence	MLARVWVRGLAATKKKPQVLVKDGPSLQDFISSASVAEAVEKYEGKLKLEKGDRRLRLPPWLKKEKILPSENENVSRLKKQLKHLKLATVCQEARCPNLGECWGGSDDSLATATIMLMGDTCTRGCKFCSVKTARAPPPLDPMEPENTSTAVASWGVEYIVLTSVDRDDLPDGGADHLRKTVQLMKLKKPELLIECLLPDFAGDKISVEKMATSGLDVYAHNIETVERLTPWVRDPRAKYRQSLDALRYAKEVSPKLITKTSIMLGLGEAEDEIKQCLADLRASNVDVVTFGQYMQPTKRHLLVKEWVTPEKFDQWAEYSKKLGFLYVASGPLVRSSYKAGEFYLKNVLRNRQN

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
Oops, there are no PTM records of LIAS_CAEEL !!

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of LIAS_CAEEL !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of LIAS_CAEEL !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of LIAS_CAEEL !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of LIAS_CAEEL !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of LIAS_CAEEL

Related Literatures of Post-Translational Modification