dbPTM

TTC27_CAEEL - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	TTC27_CAEEL
UniProt AC	P41842
Protein Name	Tetratricopeptide repeat-containing protein trd-1 {ECO:0000250\|UniProtKB:Q6P3X3}
Gene Name	trd-1 {ECO:0000312\|WormBase:T20B12.1}
Organism	Caenorhabditis elegans.
Sequence Length	771
Subcellular Localization	Cytoplasm .
Protein Description	Developmental protein required for cell fate determination in both the germline and seam cells of the developing epidermis. Specifically, involved in sex determination and may function in parallel or downstream of other sex determination factors, including tra-2 and fem-3, to promote oogenesis in its role in the regulation of the switch from spermatogenesis to oogenesis in the gonads. Also implicated in the mitosis to meiosis switch in distal tip cells..
Protein Sequence	MIPADIIASIAGLVNEKDIEKITSEYQDNIWEFVESLVTHVLASNHVGYSDYNTSSFISEELARQKLSCGLNIPNAVSKSLWALHLAHEHVEKLKDLSDIPPIGYRVILEFYLVWQQLLIDPEETIRTEIEPIMEKLRVLIAEENDAFTSEDRCQIQLEMAAVRFQFYEYDKADNLIKSASEECQLNMDLSGMMGKRTRFQQRDIAQLVLIHKDPSTTGTPLPPDSDIPQSLDMNDDTLLEQVAITEQGARVDGRTLNACQLSCLLWIARHESATHRHDVLVHERCSPVLDTVIAARRYWSIQAAALLARAELERGRVRQVDRSCTQSELVVKLQQGVDDPVLIKDRLLRTSYILASGLTPFWQSSVLLAGILNSLGCTSEALLILEKLEMWDGVIDCYKQLGQMDKAETLIRRLIEQKPNDSMLHVYLGDITRNLEYFTKAIELSDDRNARAHRSLGHLLLMDKKFEEAYKHLRRSLELQPIQLGTWFNAGYCAWKLENFKESTQCYHRCVSLQPDHFEAWNNLSAAYIRHGQKPKAWKLLQEALKYNYEHPNVWENYMLLSVDVGEFSQAIQAYHRLLDMNKRGADDEVLELIAQTLLRREAEISMDESEDKAQNEAENRKEKEEMIKLLARISANHQTLSPKTLRVYALLKKPSVLSSETRTEFEKYVRLLEKSLAAANGKLTWPKEEKLALEVVETAVRLAEDRLELAKFIASDTSVKEASAKVRLSLRGILTRLDKDSGSRVSGDETEKLQEIVEVAKSLLDSVAI

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
Oops, there are no PTM records of TTC27_CAEEL !!

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of TTC27_CAEEL !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of TTC27_CAEEL !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of TTC27_CAEEL !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of TTC27_CAEEL !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of TTC27_CAEEL

Related Literatures of Post-Translational Modification