COS1_YEAST - dbPTM
COS1_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID COS1_YEAST
UniProt AC P53822
Protein Name Protein COS1
Gene Name COS1
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 381
Subcellular Localization Membrane
Multi-pass membrane protein.
Protein Description
Protein Sequence MKENELKNEKSVDVLSFKQLESQKIVLPQDLFRSSFTWFCYEIYKSLAFRIWMLLWLPLSVWWKLSNNCIYPLIVSLLVLFLGPIFVLVICGLSRKRSLSKQLIQFCKEVTENTPSSDPHDWEVVAANLNSYLYENKAWNTKYFFFNAMVCQEAFRTTLLEPFSLKKDEAAKVKSFKDSVPYIEEALGVYFREVEKQWKLFNSEKSWSPVGLEDAKLPKEAYRFKLTWFLKRISNIFMLIPFLNFLCCIYVSRGMCLLLRTFYLGWILFMLVQGFQNMRMIVLSVKMEHKMQFLSTIINEQESGANGWDEIAKKMNRYLFEKKVWKNEEFFFDGIDCEWFFSHFFYRVLSAKKSMRALSLNVELWPYIKEAQLSCSEESLA
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
7Ubiquitination-MKENELKNEKSVDV
-CCHHHCCCCCCCCE		57.8124961812
10UbiquitinationENELKNEKSVDVLSF
HHHCCCCCCCCEEEH		66.2423749301
11PhosphorylationNELKNEKSVDVLSFK
HHCCCCCCCCEEEHH		19.8522890988
16PhosphorylationEKSVDVLSFKQLESQ
CCCCCEEEHHHHHHC		30.1922369663
18UbiquitinationSVDVLSFKQLESQKI
CCCEEEHHHHHHCCE		51.0723749301
199UbiquitinationREVEKQWKLFNSEKS
HHHHHHHHHHCCCCC		40.4823749301
205UbiquitinationWKLFNSEKSWSPVGL
HHHHCCCCCCCCCCH		57.9823749301
216UbiquitinationPVGLEDAKLPKEAYR
CCCHHCCCCCHHHHH		77.1023749301
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of COS1_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of COS1_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of COS1_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
FAB1_YEASTFAB1genetic
23891562
NU170_YEASTNUP170genetic
27708008
YBM3_YEASTYBR013Cgenetic
27708008
MBA1_YEASTMBA1genetic
27708008
YB9Z_YEASTYBR284Wgenetic
27708008
RM01_YEASTMRPL1genetic
27708008
IRC4_YEASTIRC4genetic
27708008
YJ90_YEASTYJR120Wgenetic
27708008
PEX13_YEASTPEX13genetic
27708008
CST9_YEASTCST9genetic
27708008
PHO80_YEASTPHO80genetic
27708008
KPC1_YEASTPKC1genetic
27708008
MOB2_YEASTMOB2genetic
27708008
MOB1_YEASTMOB1genetic
27708008
KTHY_YEASTCDC8genetic
27708008
PRP19_YEASTPRP19genetic
27708008
SEC22_YEASTSEC22genetic
27708008
PGA3_YEASTPGA3genetic
27708008
ROT1_YEASTROT1genetic
27708008
SEC63_YEASTSEC63genetic
27708008
NAB3_YEASTNAB3genetic
27708008
HRR25_YEASTHRR25genetic
27708008
MED10_YEASTNUT2genetic
27708008
SHE1_YEASTSHE1genetic
27708008
YMC2_YEASTYMC2genetic
27708008
ICS2_YEASTICS2genetic
27708008
YSY6_YEASTYSY6genetic
27708008
DTR1_YEASTDTR1genetic
27708008
RS6A_YEASTRPS6Bgenetic
27708008
RS6B_YEASTRPS6Bgenetic
27708008
RV161_YEASTRVS161genetic
27708008
RIM1_YEASTRIM1genetic
27708008
RBSK_YEASTRBK1genetic
27708008
IMG2_YEASTIMG2genetic
27708008
RPN4_YEASTRPN4genetic
27708008
MCH1_YEASTMCH1genetic
27708008
TRMB_YEASTTRM8genetic
27708008
PAA1_YEASTPAA1genetic
27708008
TPS2_YEASTTPS2genetic
27708008
VPS41_YEASTVPS41genetic
27708008
MTH1_YEASTMTH1genetic
27708008
PT122_YEASTPET122genetic
27708008
SLT2_YEASTSLT2genetic
27708008
MED20_YEASTSRB2genetic
27708008
HTD2_YEASTHTD2genetic
27708008
KTR7_YEASTKTR7genetic
27708008
YIT6_YEASTYIR016Wgenetic
27708008
JEM1_YEASTJEM1genetic
27708008
BLI1_YEASTBLI1genetic
27708008
DCOR_YEASTSPE1genetic
27708008
RIC1_YEASTRIC1genetic
27708008
SEC72_YEASTSEC72genetic
27708008
BUD6_YEASTBUD6genetic
27708008
VIP1_YEASTVIP1genetic
27708008
RS3A1_YEASTRPS1Agenetic
27708008
SST2_YEASTSST2genetic
27708008
SRC1_YEASTSRC1genetic
27708008
GSF2_YEASTGSF2genetic
27708008
FMP42_YEASTYMR221Cgenetic
27708008
AF9_YEASTYAF9genetic
27708008
SWM2_YEASTSWM2genetic
27708008
VPS27_YEASTVPS27genetic
27708008
NTH2_YEASTNTG2genetic
27708008
SKM1_YEASTSKM1genetic
27708008
GRE2_YEASTGRE2genetic
27708008
WHI2_YEASTWHI2genetic
27708008
CY1_YEASTCYT1genetic
27708008
BUD21_YEASTBUD21genetic
27708008
MKK2_YEASTMKK2genetic
27708008
COX10_YEASTCOX10genetic
27708008
NCBP2_YEASTCBC2genetic
27708008
PHSG_YEASTGPH1genetic
27708008
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of COS1_YEAST

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Related Literatures of Post-Translational Modification

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