LUZP4_HUMAN - dbPTM
LUZP4_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID LUZP4_HUMAN
UniProt AC Q9P127
Protein Name Leucine zipper protein 4
Gene Name LUZP4
Organism Homo sapiens (Human).
Sequence Length 313
Subcellular Localization Nucleus . Cytoplasm . In nuclear speckles. Relocalizes to the cytoplasm during cell division.
Protein Description Export adapter involved in mRNA nuclear export in cancer cells. Binds and enhances the RNA-binding activity of the nuclear RNA export factor NXF1. Can restore mRNA export function in cells compromised by loss of mRNA export adapters. [PubMed: 25662211]
Protein Sequence MASFRKLTLSEKVPPNHPSRKKVNFLDMSLDDIIIYKELEGTNAEEEKNKRQNHSKKESPSRQQSKAHRHRHRRGYSRCRSNSEEGNHDKKPSQKPSGFKSGQHPLNGQPLIEQEKCSDNYEAQAEKNQGQSEGNQHQSEGNPDKSEESQGQPEENHHSERSRNHLERSLSQSDRSQGQLKRHHPQYERSHGQYKRSHGQSERSHGHSERSHGHSERSHGHSERSHGHSKRSRSQGDLVDTQSDLIATQRDLIATQKDLIATQRDLIATQRDLIVTQRDLVATERDLINQSGRSHGQSERHQRYSTGKNTITT
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
76PhosphorylationRHRHRRGYSRCRSNS
HHHHHHHHHHHHCCC		7.3622817900
81PhosphorylationRGYSRCRSNSEEGNH
HHHHHHHCCCCCCCC		48.6222210691
83PhosphorylationYSRCRSNSEEGNHDK
HHHHHCCCCCCCCCC		37.9722210691
121PhosphorylationQEKCSDNYEAQAEKN
CCCCCCCHHHHHHHH		20.03-
232PhosphorylationSHGHSKRSRSQGDLV
CCCCCCCCCCCCCCC		39.7725693802
234PhosphorylationGHSKRSRSQGDLVDT
CCCCCCCCCCCCCCC		39.5014702039
276PhosphorylationTQRDLIVTQRDLVAT
HHHHHEEEHHHHHHH		15.7624719451
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of LUZP4_HUMAN !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of LUZP4_HUMAN !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of LUZP4_HUMAN !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
RCOR3_HUMANRCOR3physical
25416956
KR109_HUMANKRTAP10-9physical
25416956
KR108_HUMANKRTAP10-8physical
25416956
KR103_HUMANKRTAP10-3physical
25416956
ACTN4_HUMANACTN4physical
25662211
LIMA1_HUMANLIMA1physical
25662211
MYPT1_HUMANPPP1R12Aphysical
25662211
SVIL_HUMANSVILphysical
25662211
ZO1_HUMANTJP1physical
25662211
LUZP4_HUMANLUZP4physical
25662211
LUZP1_HUMANLUZP1physical
25662211
IF4A3_HUMANEIF4A3physical
25662211
PININ_HUMANPNNphysical
25662211
ACINU_HUMANACIN1physical
25662211
AMOT_HUMANAMOTphysical
25662211
PDLI1_HUMANPDLIM1physical
25662211
AIF1L_HUMANAIF1Lphysical
25662211
DX39B_HUMANDDX39Bphysical
25662211
THOC4_HUMANALYREFphysical
25662211
ACTN1_HUMANACTN1physical
25662211
SRRT_HUMANSRRTphysical
25662211
RS13_HUMANRPS13physical
25662211
H2A1D_HUMANHIST1H2ADphysical
25662211
RNPS1_HUMANRNPS1physical
25662211
PAWR_HUMANPAWRphysical
25662211
SRSF7_HUMANSRSF7physical
25662211
H2B1D_HUMANHIST1H2BDphysical
25662211
H2B1C_HUMANHIST1H2BDphysical
25662211
SRSF1_HUMANSRSF1physical
25662211
RS7_HUMANRPS7physical
25662211
BCLF1_HUMANBCLAF1physical
25662211
CALD1_HUMANCALD1physical
25662211
RBMX_HUMANRBMXphysical
25662211
RBM8A_HUMANRBM8Aphysical
25662211
H2B1B_HUMANHIST1H2BBphysical
25662211
K1671_HUMANKIAA1671physical
25662211
MGN_HUMANMAGOHphysical
25662211
ZO2_HUMANTJP2physical
25662211
ABLM1_HUMANABLIM1physical
25662211
CYTSA_HUMANSPECC1Lphysical
25662211
H31T_HUMANHIST3H3physical
25662211
AKAP2_HUMANAKAP2physical
25662211
SHKB1_HUMANSHKBP1physical
25662211
ST38L_HUMANSTK38Lphysical
25662211
SAP18_HUMANSAP18physical
25662211
ERH_HUMANERHphysical
25662211
PDIP3_HUMANPOLDIP3physical
25662211
SRGP2_HUMANSRGAP2physical
25662211
CSK21_HUMANCSNK2A1physical
25662211
RS15_HUMANRPS15physical
25662211
BAF_HUMANBANF1physical
25662211
EFHD1_HUMANEFHD1physical
25662211
PLST_HUMANPLS3physical
25662211
FUS_HUMANFUSphysical
25662211
RFA1_HUMANRPA1physical
25662211
PPR18_HUMANPPP1R18physical
25662211
SRSF6_HUMANSRSF6physical
25662211
THOC5_HUMANTHOC5physical
25662211
RL27A_HUMANRPL27Aphysical
25662211
DDX5_HUMANDDX5physical
25662211
PDLI7_HUMANPDLIM7physical
25662211
SRS10_HUMANSRSF10physical
25662211
RL26_HUMANRPL26physical
25662211
H2AY_HUMANH2AFYphysical
25662211
DDX1_HUMANDDX1physical
25662211
THOC1_HUMANTHOC1physical
25662211
DDX21_HUMANDDX21physical
25662211
RL22_HUMANRPL22physical
25662211
RSSA_HUMANRPSAphysical
25662211
RL24_HUMANRPL24physical
25662211
TR150_HUMANTHRAP3physical
25662211
TMOD2_HUMANTMOD2physical
25662211
COR1B_HUMANCORO1Bphysical
25662211
CSRP2_HUMANCSRP2physical
25662211
RL35_HUMANRPL35physical
25662211
PP1B_HUMANPPP1CBphysical
25662211
COF2_HUMANCFL2physical
25662211
H13_HUMANHIST1H1Dphysical
25662211
THOC2_HUMANTHOC2physical
25662211
CHTOP_HUMANCHTOPphysical
25662211
Drug and Disease Associations
Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of LUZP4_HUMAN

loading...

Related Literatures of Post-Translational Modification

TOP
© 2024 Institute of Bioinformatics and Systems Biology, NYCU | Designed by : BiOmics Laboratory