NSF2_DROME - dbPTM
NSF2_DROME - PTM Information in dbPTM
Basic Information of Protein
UniProt ID NSF2_DROME
UniProt AC P54351
Protein Name Vesicle-fusing ATPase 2
Gene Name Nsf2
Organism Drosophila melanogaster (Fruit fly).
Sequence Length 752
Subcellular Localization Cytoplasm .
Protein Description Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seems to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin (By similarity)..
Protein Sequence MSIEKAHRMRAIKCPTDELSLTNKAIVNVSDFTEEVKYVDISPGPGLHYIFALEKISGPELPLGHVGFSLVQRKWATLSINQEIDVRPYRFDASADIITLVSFETDFLQKKTTTQEPYDSDEMAKEFLMQFAGMPLTVGQTLVFQFKDKKFLGLAVKTLEAVDPRTVGDSLPKTRNVRFGRILGNTVVQFEKAENSVLNLQGRSKGKIVRQSIINPDWDFGKMGIGGLDKEFNAIFRRAFASRVFPPELVEQLGIKHVKGILLYGPPGTGKTLMARQIGTMLNAREPKIVNGPQILDKYVGESEANIRRLFAEAEEEEKRLGPNSGLHIIIFDEIDAICKARGSVAGNSGVHDTVVNQLLAKIDGVEQLNNILVIGMTNRRDMIDEALLRPGRLEVQMEISLPNEQGRVQILNIHTKRMRDFNKIASDVDNNEIAAKTKNFSGAELEGLVRAAQSTAMNRLIKADSKVHVDPEAMEKLRVTRADFLHALDNDIKPAFGAAQEMLENLLARGIINWGPPVTELLEDGMLSVQQAKATESSGLVSVLIEGAPNSGKSALAANLAQLSDFPFVKVCSPEDMVGFTESAKCLHIRKIFDDAYRSTLSCIVVDNVERLLDYGPIGPRYSNLTLQALLVLLKKQPPKGRKLLILCTSSRRDVLEEMEMLSAFTSVLHVSNLSTPENVLAVLDDSDLFSPEELQSIARKMAGKRLCIGIKKLLALIDMIRQSEPHQRVIKFLSKMEEEGGLEMDRVQGH
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
212PhosphorylationKGKIVRQSIINPDWD
CCCEEEEECCCCCCC
18.1819429919

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of NSF2_DROME !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of NSF2_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of NSF2_DROME !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
SNAP_DROMEalphaSnapphysical
22036573
USE1_DROMEUse1physical
22036573
SLY1_DROMESlhphysical
22036573
GOSR2_DROMEMembrinphysical
22036573
RBF_DROMERbfgenetic
15834148
NOTCH_DROMENgenetic
11356016
OVO_DROMEovogenetic
15834148
ACT1_DROMEAct5Cgenetic
15834148
WUHO_DROMEwuhogenetic
15834148
C3G_DROMEC3Ggenetic
15834148
FRIZ4_DROMEfz4genetic
15834148
MOEH_DROMEMoegenetic
15834148
FEND_DROMEfendgenetic
15834148
UBE2N_DROMEbengenetic
15834148
NETB_DROMENetBgenetic
15834148
PORCN_DROMEporgenetic
11356016
CP6V1_DROMECyp6v1genetic
15834148
WNTG_DROMEwggenetic
11356016
RS2_DROMERpS2genetic
15834148
BIB_DROMEbibgenetic
11356016
TRM1_DROMECG6388genetic
15834148
STX5_DROMESyx5genetic
12435359
CHK1_DROMEgrpgenetic
15834148
RPAC2_DROMEl(2)37Cggenetic
15834148
BRAT_DROMEbratgenetic
15834148
SPITZ_DROMEspigenetic
15834148
PHTF_DROMEphtfgenetic
15834148
UBL5_DROMEublgenetic
15834148
SYB_DROMESybgenetic
11356016
LAMA_DROMELanAgenetic
15834148
UFD1_DROMEUfd1-likegenetic
15834148
LONM_DROMELongenetic
15834148
POLO_DROMEpologenetic
15834148
SNAP_DROMEalphaSnapgenetic
15834148
FNG_DROMEfnggenetic
11356016
DL_DROMEDlgenetic
11356016
E2F1_DROMEE2fgenetic
15834148
STX1A_DROMESyx1Agenetic
11356016
SERR_DROMESergenetic
11356016
CDSA_DROMECdsAgenetic
15834148
LOLA1_DROMElolagenetic
15834148
LOLA2_DROMElolagenetic
15834148
LOLA3_DROMElolagenetic
15834148
LOLA4_DROMElolagenetic
15834148
LOLA6_DROMElolagenetic
15834148
LOLA5_DROMElolagenetic
15834148
WECH_DROMEwechgenetic
15834148
CPO_DROMEcpogenetic
15834148
NSF1_DROMEcomtgenetic
11333235

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of NSF2_DROME

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Related Literatures of Post-Translational Modification

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